Uses of eggshells to treat osteoporosis
اUses of eggshells to treat osteoporosis
Uses of eggshells to treat osteoporosis
Unwanted eggshells appear to be an important material for making safe and effective bone grafts for humans, according to New Atlas, citing the journal Smart Materials in Medicine.
In order to create a new material for safe and effective bone grafting, the researchers resorted to chicken eggshells, which are widely available and inexpensive.
Researchers have developed a new method of dissolution and precipitation to form amorphous calcium phosphate (ACP) particles from chicken eggshells, which are essential for the formation of mineralized bone — that is, hard and strong — and had previously been used as a substitute for bone due to its components.
Perfect raw material
For his part, the lead researcher of the study, Kinali Ma, a professor at the Department of Biomaterials at the University of Oslo, said: “Eggshells are an ideal raw material for the manufacture of bone grafting materials because they contain many components of calcium and phosphorus. Some trace elements associated with bone regeneration, such as magnesium and strontium, are also found in eggshells.”
The researchers embedded the ACP particles into a XNUMXD spheroid to better analyze the bone formation activity of the particles through the interaction between host bone tissue and grafting material. They discovered that ACP molecules in eggshells in vitro actually interacted with the cells that build bone, along with the advantages that they were non-toxic, immunocompliant, and effective in promoting bone regeneration.
Promising technology
"This technology holds promise for providing an unlimited supply of bioactive and sustainable bone grafting materials while reducing environmental pollution," said Harvard Justin Hauge, from the University of Oslo, Norway and corresponding researcher on the study.
The researchers hope that their findings will encourage further research into the use of ordinary food waste as biomaterials.
It is noteworthy that the common method of bone grafting all over the world is to fill voids or gaps in the bones by means of bone graft materials from various sources, including autografts from the bones of the same person who is being operated on, or from grafts from donor bones, which are collected during Surgical procedures such as hip replacement that are sterilized for use in other patients' bone grafts.
Bone grafts are also provided from inanimate bones of animals such as cows or pigs, called xenogeneic, which are processed at high temperatures to sterilize and not be rejected by the human body, and are usually of lower quality than autografts or donors.