The cause of clots from the corona vaccine

The cause of clots from the corona vaccine

Scientists have identified a possible cause of blood clots from the Corona vaccine from the company AstraZeneca, after the use of the vaccine was limited globally to prevent rare side effects.

Preclinical research, conducted with AstraZeneca, has found that an interaction between the vaccine and a protein known as platelet factor 4 could be behind the coagulopathy with thrombocytopenia syndrome, according to a study published Wednesday in Science Advances by scientists from the US and UK. .

The global delivery of the AstraZeneca vaccine, which was developed jointly with the University of Oxford, has been slowed globally due to a possible link between the vaccine and rare cases of blood clots, as the United Kingdom has limited its use for those over 40, while the United States has not allowed the vaccine to be given.

And in May, German scientists published a hypothesis that the side effect is related to the adenovirus vector used by the vaccination.

Clots were more common after the first than the second dose, with 426 cases reported to the UK regulator as of 17 November from more than 24 million doses given.

"Although the research is not conclusive, it does provide interesting insights, and is exploring ways to take advantage of these findings as part of our efforts to eliminate this extremely rare side effect," the company said in a statement.

The company explained that the mechanism identified does not prove to be the cause of the rare blood clot and that most individuals who have antibodies to PF4 will not develop clots.

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