Jiyya mai alƙawarin ga marasa lafiya na Parkinson

Jiyya mai alƙawarin ga marasa lafiya na Parkinson

Cutar Parkinson cuta ce da ta daɗe tana shafar ƙwayoyin jijiya waɗanda ke samar da dopamine, sinadaran da ke watsa sigina tsakanin wuraren da ke cikin kwakwalwa.

Dopamine kuma yana da alhakin santsi da daidaitawar motsin tsoka na jiki. Kuma lokacin da matakansa suka fara raguwa, wannan yana rinjayar motsin jiki.

Duk da yake babu magani ga cutar Parkinson, akwai jiyya da ke kawar da alamun bayyanar cututtuka, ciki har da magunguna, ci gaba da motsa jiki da jiyya na dabi'a waɗanda ke mayar da hankali kan daidaito da mikewa, da sauransu.

Kwayoyin da aka gyara ta kwayoyin halitta

Amma sabon bincike, gabatar da taron shekara-shekara na al'ummar Amurka don gwajin magunguna da masu shayarwa a Philadelphia na iya zama ingantacciyar magani ga Parkinson's.

Daki-daki, masu bincike sun kirkiro kwayoyin cuta wadanda za su iya samar da ingantaccen tushen magunguna a cikin hanjin mara lafiya, kuma gwajin dabbobi ya tabbatar da cewa suna da lafiya da inganci, a cewar New Atlas.

Tunanin injiniyoyin ƙwayoyin cuta don yin aiki azaman jiyya ba sabon abu bane. Shekaru da yawa, masana kimiyya sun riga sun gwada hanyoyin da za su iya keɓance ƙwayoyin cuta don dacewa da bukatun mutane, daga injiniyan ƙwayoyin cuta zuwa ɗimbin ammonia a jikin ɗan adam zuwa taimakawa ƙwayoyin cuta gano ƙwayoyin cutar kansar launin fata.

kalubale daban-daban

Amma ba shakka, kafin ra'ayin irin wannan ya shirya don amfani na yau da kullun na asibiti, dole ne a shawo kan matsaloli da yawa.

Bayar da magunguna masu sarrafawa ga mai haƙuri a cikin nau'i na allunan, syrups ko injections sananne ne. Amma iyakance haɓakar ƙwayoyin cuta masu rai waɗanda aka ƙera ta hanyar halitta don ƙirƙirar waɗannan ƙwayoyin cuta iri ɗaya a cikin hanjin ɗan adam yana ba da ƙalubale gaba ɗaya.

Sannu a hankali gaba

Sabon binciken ya ɗauki mataki na gaba a aikin injiniya wani sabon nau'in probiotic na ɗan adam E.coli Nissle 1917, wanda aka ƙera don kerawa da ci gaba da shigar da maganin cutar Parkinson da aka sani da L-DOPA a cikin hanjin majiyyaci.

L-DOPA kwayoyin halitta ne da ke aiki a matsayin mafari ga dopamine kuma ya kasance mai nasara jiyya ga marasa lafiyar Parkinson shekaru da yawa. Amma likitoci sun gano cewa kimanin shekaru 5 bayan da marasa lafiya suka karbi wannan magani, sau da yawa suna haifar da wani sakamako na gefe wanda aka sani da dyskinesia. Ana tsammanin waɗannan illolin suna da alaƙa da rashin ci gaba da samun tushen samar da magunguna ga ƙwaƙwalwa.

Don haka don magance wannan batu, sabon binciken ya bincika ko kwayoyin da ke samar da L-DOPA a cikin hanji na iya haifar da isar da ƙwayoyi zuwa kwakwalwa.

therapeutically m yawa

Kwayoyin da aka yi amfani da su sun haura wani kwayar halitta mai suna tyrosine kuma suna ɓoye L-DOPA a cikin hanjin majiyyaci, in ji Piyush Badi, mawallafi a kan binciken.

Bugu da ƙari, gwaje-gwaje da yawa a cikin beraye sun nuna cewa ƙwayoyin cuta da aka yi amfani da su sun haifar da kwanciyar hankali da daidaito na L-DOPA a cikin jini. Sannan gwaje-gwaje a cikin nau'ikan dabbobi na cutar Parkinson sun gano cewa maganin yana inganta injina da ayyukan fahimi, wanda ke nuna cewa ƙwayoyin ƙwayoyin cuta suna samar da adadin magungunan da ke da tasiri mai inganci.

Alzheimer's da damuwa

Masu binciken sun kuma yi iƙirarin cewa matakan L-DOPA da ƙwayoyin cuta ke samarwa za a iya sarrafa su daidai, ko dai ta hanyar rage adadin ƙwayoyin ƙwayoyin cuta da ake amfani da su a kullum a cikin capsules ko kuma ta hanyar yin gyare-gyaren shan sukari mai suna rhamhose, wanda kwayoyin ke buƙatar ci gaba da samarwa. L-DOPA.

Anumantha Kanthasamy, wacce ita ma mawallafin binciken, ta ce a halin yanzu kungiyar masana kimiyya na kokarin daidaita tsarin kula da wasu cututtukan da ke bukatar ci gaba da shan magunguna, kamar cutar Alzheimer da damuwa.