ʻO New Corona .. he maʻi i haku i ka hoʻohālike, ka ʻano ʻē a me nā mea kupanaha

I ka manawa e pilikia ai ka honua holoʻokoʻa ma lalo o ka maʻi Corona e puka mai nei, ke hoʻāʻo nei ka poʻe loea e hoʻokūkū i ka manawa e hoʻoponopono ai i ka mea huna o ka ʻenemi o ke kanaka, ka mea i loaʻa i ka maʻi ma mua o 44 miliona mau kānaka, a ua make ma mua o hoʻokahi miliona. ʻoiai ua ʻike ʻia ma lalo o hoʻokahi makahiki i hala no ka manawa mua ma Kina.

ʻO ka mea hou i kēia lā i ʻike ʻia e kahi noiʻi i alakaʻi ʻia e nā mea noiʻi ma ka Vagelos College of Physicians and Surgeons ma Columbia University, ka mea i ʻōlelo ua mākaukau nā maʻi corona i ka hoʻohālikelike ʻana i nā protein immune kanaka i komo i ka maʻi Covid-19 koʻikoʻi. Ua paʻi ʻia ke aʻo ʻana ma ka pūnaewele o ka puke pai Pūnaewele Pūnaewele.

He ʻeleʻele ka hoʻoilo o Corona a ua manaʻo ʻia ka pōʻino loa.

No kāna ʻaoʻao, ʻo Sagi Shapira, ke kākā'ōlelo kōkua o nā ʻōnaehana biology ma ke Kulanui o Vagelos o nā Kauka a me nā Surgeons ma Columbia University, a me ka mea noiʻi alakaʻi o ka noiʻi, i ʻōlelo ʻia i loko o kahi hōʻike i paʻi ʻia i ka Pōʻalua ma ka pūnaewele o ke kulanui: "Hoʻohana nā maʻi virus i ka hoʻohālike no ke kumu like o nā mea kanu. a me nā holoholona, ​​ʻo ia ka hoʻopunipuni," i hoʻohui ʻia: "Ua manaʻo mākou he ʻano like me ka Protein viral Hāʻawi ia iā mākou i nā ʻōlelo aʻoaʻo i ke ala o nā maʻi - me ka coronavirus novel - kumu iā lākou.

"ʻOi aku ma mua o kā mākou i manaʻo ai"

I ka hoʻohana ʻana i nā supercomputers e ʻimi i nā mimic viral me ka hoʻohana ʻana i nā polokalamu like me ka ʻike maka 7000D, ua ʻimi ʻo Shapira a me kāna hui noiʻi ma mua o 4000 mau maʻi maʻi a ʻoi aku ma mua o 6 mau pūʻali ma nā kaiaola o ka Honua a ʻike ʻia he XNUMX miliona mau hihia o nā mimic viral.

Hōʻike ke keiki i ka mālama ʻana i ka corona, e pau ka pōʻino?

Ua wehewehe pū ʻo ia "ʻo ka hoʻohālikelike ʻana he hoʻolālā laha loa ma waena o nā maʻi ma mua o kā mākou i noʻonoʻo ai. Hoʻohana ʻia ia e nā ʻano maʻi āpau, me ka nānā ʻole i ka nui o ka genome viral, pehea ka hana hou ʻana o ka maʻi, a i ʻole ka maʻi i hoʻopilikia i ka bacteria, nā mea kanu, nā inika a i ʻole nā ​​kānaka.

“ʻano akamai loa”

Ua hoʻomau ʻo ia, "Akā, ʻoi aku ka hoʻohana ʻana o kekahi mau ʻano virus ma mua o nā mea ʻē aʻe. ʻOiai ʻaʻole hoʻohana nui nā papillomavirus a me nā retrovirus, ua ʻike mākou he mea akamai loa nā coronaviruses, a ua ʻike mākou ua hoʻohālikelike lākou i nā protein ʻoi aku ma mua o 150, me nā mea he nui e hoʻomalu i ka clotting koko, kahi hui o nā protein immune e kōkua i nā pathogens. . ʻO nā maʻi e luku ai, "e ʻike ana: "Ua manaʻo mākou ma ka hoʻohālikelike ʻana i ka hoʻopiha ʻana o ke kino a me nā protein clotting, hiki i nā coronaviruses ke hoʻohuli i kēia mau ʻōnaehana i kahi kūlana overactive a hoʻoulu i nā maʻi a mākou e ʻike ai i nā maʻi maʻi."

He mea nui ia i ka wā o ka maʻi maʻi, ua maopopo ka nui o nā mea maʻi me Covid-19 i loaʻa i nā pilikia coagulation a ke mālama ʻia nei kekahi o lākou me nā anticoagulants a me nā lāʻau lapaʻau e kaupalena ana i ka hoʻōla ʻana o nā mea hoʻohui.

Ma kahi pepa ʻokoʻa i paʻi ʻia ma Nature Medicine, ua ʻike nā mea noiʻi o Columbia University i nā hōʻike e pili ana ka hana a me ka genetic dysregulation o ka ʻōnaehana hoʻopihapiha a me nā protein clotting me ka maʻi COVID-19 koʻikoʻi. ʻO ka ʻōnaehana hoʻohui, ʻo ia ka ʻāpana o ka ʻōnaehana pale e hoʻonui ai i ka hiki o nā antibodies a me nā phagocytes e hoʻoneʻe i nā microbes a me nā cell i pōʻino mai ke kino. Ua ʻike lākou he ʻoi aku ka nui o ka make ʻana o ka poʻe me ka macular degeneration (pili ʻia me ka hoʻoulu ʻana o ka ʻōnaehana complement) mai COVID-19, ʻoi aku ka ikaika o ka complement a me ka clotting genes i nā mea maʻi me kēia maʻi, a ʻo nā poʻe me kekahi mau hoʻololi a me ka hoʻololi ʻana. ʻoi aku ka nui o kēia mau Genes i ka haukapila no kēia maʻi pū kekahi.

Eia kekahi, ua noʻonoʻo ʻo Shapira ʻo ka noiʻi ʻana i nā hana protein viral a me ka mimicry e hōʻike ana i ke aʻo ʻana e pili ana i ka biology kumu o ka maʻi maʻi ke ala e loaʻa ai ka ʻike i ka hopena o nā maʻi i ka maʻi a ʻo wai paha ka pilikia.

Ua hōʻike ʻia mai ka puka mua ʻana o kēia pepa i ka pūnāwai o kēia makahiki i kahi mana mua, ua ʻike pū nā mea noiʻi ʻē aʻe i nā loulou ma waena o ke koʻikoʻi hoʻohui a me Covid-19, a ua hoʻomaka ʻia nā hoʻokolohua lapaʻau he nui o nā inhibitors o kēia ʻōnaehana.