Ka mālama ʻana i nā maʻi maʻi me ka corona e...?

ʻO kahi hoʻokolohua lapaʻau, nā hopena i paʻi ʻia, ma ka Pōʻakolu, i loko o kahi puke moʻolelo lapaʻau kūikawā, ua hōʻike ʻia ka lāʻau "tofacitinib" no ka mālama ʻana i nā maʻi o ka maʻi i hōʻike i nā hopena hoʻohiki i ka mālama ʻana i nā mea maʻi me nā hōʻailona koʻikoʻi o ka maʻi Covid-19.

A ʻo ka hoʻokolohua lapaʻau, nā hopena i paʻi ʻia ma ka "New England Journal of Medicine," i hana ʻia ma 289 poʻe i mālama ʻia i nā halemai ma 15 mau wahi like ʻole ma Brazil ma muli o nā hōʻailona koʻikoʻi o Covid-19.

ʻO ka hapalua o kēia mau maʻi i hāʻawi ʻia i ka tofacitinib (ʻelua mau papa 10 mg i kēlā me kēia lā) i hui pū ʻia me ka mālama olakino maʻamau a ʻo ka hapa ʻē aʻe i hāʻawi ʻia i kahi placebo me ka mālama ola like.

Ma hope o 28 lā, 18% o ka hui i loaʻa i ka lāʻau i hoʻomohala i ka hanu hanu (e like me ke koi ʻana i ka intubation a i ʻole ke komo ʻana i kahi respirator) a i make paha, ke hoʻohālikelike ʻia me 29% o ka hui placebo.

Ma nā mea a pau, ua make ka 5.5% o nā maʻi placebo, i hoʻohālikelike ʻia me 2.8% i ka hui tofacitinib.

Kūʻai ʻia ʻo Tofacitinib ma lalo o nā hōʻailona like ʻole, me Zeljans, nona ka hui lāʻau lapaʻau ʻAmelika ʻo Pfizer.

"Ua paipai ʻia mākou e nā hopena mua o kā mākou hoʻāʻo ʻana i ka tofacitinib i nā mea maʻi i mālama ʻia me ka maʻi pneumonia i hoʻokumu ʻia e Covid-19," wahi a Otavio Berwanger, he kauka ma ka Halemai Albert Einstein ma ʻIseraʻela nāna i alakaʻi i ka hoʻokolohua lapaʻau me ka hui pū me Pfizer.

Ua ʻae ʻia ʻo Tofacitinib no ka hoʻohana ʻana ma ʻAmelika Hui Pū ʻIa e mālama i ka maʻi rheumatoid, psoriatic arthritis, a me ka ulcerative colitis.

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