Kev haus luam yeeb tsis yog ib qho tseem ceeb ntawm kev mob ntsws cancer

Kev haus luam yeeb tsis yog ib qho tseem ceeb ntawm kev mob ntsws cancer

Qee cov pa phem hauv huab cua zoo li "tus neeg tua neeg zais", vim tias lawv tuaj yeem ua rau ntau tus mob qog noj ntshav hauv cov neeg tsis haus luam yeeb, los ntawm cov txheej txheem piav qhia los ntawm kev tshawb fawb luam tawm hnub Saturday, thiab ncav cuag lawv txoj kev nkag siab yog " kauj ruam tseem ceeb rau kev tshawb fawb thiab zej zog, "raws li ib pab pawg kws tshaj lij.

Cov kws tshawb fawb los ntawm lub koom haum Francis Crick thiab University College London tau piav qhia tias cov khoom zoo (tsawg dua 2,5 microns, kwv yees li txoj kab uas hla ntawm cov plaub hau), uas yog suav tias yog cov ua rau kev hloov pauv huab cua, ua rau muaj mob qog noj ntshav hauv cov hlwb ntawm lub ntsws.

stealth killer

Cov khoom zoo hauv cov pa roj, nres cov plua plav lossis cov pa taws los ntawm cov roj fossil tuaj yeem piv rau "tus neeg tua neeg zais", hais tias Charles Swanton ntawm lub koom haum Francis Crick, uas tau nthuav tawm cov txiaj ntsig ntawm kev tshawb fawb no, uas tseem tsis tau raug tshuaj xyuas los ntawm lwm cov kws tshawb fawb. Thaum lub rooj sib tham txhua xyoo ntawm European Society of Medical Oncology, muaj nyob rau hauv Paris rau 13 Cuaj hlis.

Thaum tus xibfwb Swanton tau ceeb toom tias qhov kev puas tsuaj ntawm huab cua muaj kuab paug tau paub ntev ntev, nws tau sau tseg tias cov kws tshawb fawb tau "tsis paub meej tias cov pa phem no ncaj qha ua rau mob qog noj ntshav."

Cov kws tshawb nrhiav thawj zaug tau kawm cov ntaub ntawv ntawm ntau dua 460 tus neeg los ntawm tebchaws Askiv, Kaus Lim Qab Teb thiab Taiwan, thiab pom tias muaj kev sib koom ua ke ntawm kev nthuav dav ntawm cov khoom zoo thiab muaj kev pheej hmoo ntawm mob qog noj ntshav.

250 qauv

Txawm li cas los xij, qhov kev tshawb pom tseem ceeb tshaj plaws yog kev nkag siab txog cov txheej txheem uas cov pa phem no ua rau mob qog noj ntshav hauv cov neeg tsis haus luam yeeb.

Hauv kev soj ntsuam kuaj cov nas, cov kws tshawb fawb tau pom tias cov khoom ua rau muaj kev hloov pauv hauv ob lub noob, uas yog epidermal growth factor receptor (EGFR) thiab Keras (KRAS), uas twb tau txuas rau mob ntsws cancer.

Tom qab ntawd cov kws tshawb fawb tau tshuaj xyuas txog 250 cov qauv ntawm tib neeg lub ntsws noj qab haus huv uas tsis tau raug cov carcinogens los ntawm kev haus luam yeeb lossis muaj kuab paug hnyav. Kev hloov pauv hauv EGFR noob tau tshwm sim hauv 18 feem pua ​​​​ntawm cov qauv, thiab hloov pauv hauv KRAS hauv 33 feem pua ​​​​ntawm lawv.

"tsis paub"

Prof Swanton tau hais tias "cov kev hloov pauv no yuav tsis txaus rau lawv tus kheej ua rau mob qog noj ntshav, tab sis thaum lub xov tooj ntawm tes raug kev sib kis, nws yuav ua rau muaj qee yam tshuaj tiv thaiv" inflammatory. Nws hais ntxiv tias "lub cell yuav ua rau mob qog noj ntshav" yog tias nws "muaj kev hloov pauv."

Swanton, uas yog tus thawj coj ntawm txoj kev tshawb fawb tus txhawb nqa tseem ceeb, Cancer Research UK, tau hais tias txoj kev tshawb no yog "kev txiav txim siab ntawm cov txheej txheem lom neeg ntawm dab tsi yog qhov tsis paub."

Nws tau ntseeg tias kev kis tus kab mob ua rau mob qog noj ntshav, xws li cov uas tshwm sim los ntawm cov pa luam yeeb lossis cov pa phem, ua rau muaj kev hloov pauv hauv cov hlwb, ua rau cov qog nqaij hlav thiab ua rau lawv loj hlob.

Tus thawj coj ntawm Kev Tiv Thaiv Kab Mob Cancer ntawm lub koom haum Gustave Rossi Sozette Delalog tau sau tseg tias qhov kev tshawb pom ntawm qhov kev tshawb fawb no yog "kev hloov pauv hloov", vim tias "tsis muaj pov thawj yav dhau los ntawm qhov kev hloov pauv no."

Tus kws kho mob oncologist no, uas tau raug txib los tham txog txoj kev kawm thaum lub rooj sib tham, tau hais tias nws yog "qib tseem ceeb rau kev tshawb fawb", vam tias nws yuav yog li "rau zej zog ib yam", thiab xav tias nws "qhib qhov rooj dav rau kev paub. tab sis kuj rau kev tiv thaiv. "

Txo cov pa phem

Prof Swanton tau hais tias cov kauj ruam tom ntej yuav yog "kom nkag siab tias vim li cas qee qhov ntawm lub ntsws hloov pauv hloov mus ua qog noj ntshav tom qab raug cov pa phem".

Ntau tus kws tshawb fawb tau hais tias txoj kev tshawb fawb no tau lees paub tias kev txo cov pa phem kuj tseem ceeb rau kev noj qab haus huv.

Swanton tau hais tias "Peb muaj kev xaiv ntawm kev haus luam yeeb lossis tsis yog, tab sis peb tsis tuaj yeem xaiv cov huab cua uas peb ua pa," Nws yog qhov teeb meem thoob ntiaj teb vim tias tus naj npawb ntawm cov neeg raug cov pa phem tsis zoo yuav muaj tsib npaug ntau dua li cov neeg tau haus luam yeeb. "

Ntau tshaj 90 feem pua ​​​​ntawm cov pej xeem hauv ntiaj teb raug cuam tshuam rau yam uas Lub Koom Haum Saib Xyuas Kev Noj Qab Haus Huv (World Health Organization) piav qhia tias yog cov pa phem ntau dhau uas muaj cov khoom me me.