Cov nanobodies puas yuav daws tau Corona?

Hauv thawj qhov kev sim ntawm nanobodies uas zoo li cov tshuaj tiv thaiv kab mob monoclonal, tab sis me dua, ruaj khov thiab pheej yig dua los tsim, cov kws tshawb fawb los ntawm American University of Pittsburgh Tsev Kawm Ntawv Tshuaj tau pom tias nqus tau nanobodies uas tsom rau "ntsiav" protein ntawm tus mob coronavirus, tuaj yeem ua tau. Txhawm rau tiv thaiv thiab kho mob hnyav.

Nyob rau hauv cov ntsiab lus ntawm txoj kev tshawb no luam tawm nyob rau hauv phau ntawv journal "Science Advances", thiab ua nyob rau hauv hamsters, cov kws tshawb fawb pom tau hais tias tsawg npaum li cas ntawm ib tug aerobic nanobody hu ua Nanobody - 21 "PiN - 21", uas yuav nqus tau pa tiv thaiv hamsters los ntawm qhov hnyav hnyav. Kev poob feem ntau cuam tshuam nrog kev kis tus kab mob hnyav.Thiab nws txo tus naj npawb ntawm cov kab mob sib kis hauv qhov ntswg kab noj hniav, caj pas thiab ntsws los ntawm ib lab zaug, piv rau cov placebo kev kho mob uas siv cov nanobody uas tsis muaj qhov cuam tshuam ntawm tus kab mob.

Nws tau piav qhia tias los ntawm kev siv txoj kev nqus pa uas tuaj yeem muab ncaj qha mus rau qhov chaw kis kab mob hauv lub ntsws thiab lub ntsws, peb tuaj yeem ua rau kev kho mob zoo dua, taw qhia tias kev cia siab zoo heev, tshwj xeeb tshaj yog tom qab nanobody (PiN - 21) tau lees paub tias. Nws tuaj yeem tiv thaiv cov kab mob hnyav heev, thiab tuaj yeem tiv thaiv kev kis tus kabmob ntawm ib tus neeg mus rau lwm tus.

Tshuaj tiv thaiv yog qhov kev daws teeb meem zoo tshaj plaws

Cov kws tshawb fawb yuav tsum tau kov yeej ntau yam kev sib tw hauv qhov kev tshawb fawb no, vim tias cov nanoparticles yuav tsum nkag mus tob rau hauv lub ntsws, thiab cov khoom siv kho mob yuav tsum muaj me me kom lawv tsis txhob sib sau ua ke thiab muaj zog txaus los tiv thaiv kev kub ntxhov.

PiN-21 nanobodies, uas yog kwv yees li 4 npaug me dua li cov tshuaj tiv thaiv kab mob monoclonal uas muaj kev ruaj ntseg tshwj xeeb, tau txais txiaj ntsig zoo rau txoj haujlwm no, yog qhov pheej yig dua los tsim, thiab tuaj yeem tsim sai sai rau cov kab mob hloov pauv sai.

Tsis tas li ntawd, cov kws tshawb fawb tau taw qhia tias cov nanobodies thiab cov tshuaj tiv thaiv ua kom sib ntxiv thiab tsis sib tw, thiab cov tshuaj tiv thaiv tseem yog txoj hauv kev zoo tshaj plaws los tiv thaiv kev kis tus kab mob ntawm ib tus neeg mus rau lwm tus.

Nws tau piav qhia tias cov nanobodies tsuas yog siv tau los kho cov neeg uas twb muaj mob thiab tsis tuaj yeem txhaj tshuaj tiv thaiv rau lwm yam kev kho mob.

Lwm yam ntsiab lus:

Koj ua li cas nrog ib tug neeg uas ntse tsis quav ntsej koj?

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