Kuwonekera mosalekeza ku zotsatira za zolimbikitsa zimakhudza mimba!!

Kuwonekera mosalekeza ku zotsatira za zolimbikitsa zimakhudza mimba!!

Kafukufuku watsopano wagwirizanitsa kukhudzana ndi phthalates, gulu la mankhwala, asanatenge mimba ndi ubereki wa amayi. Zotsatira za phunziroli zimawonjezera umboni wochuluka wokhudzana ndi zotsatira zoipa za mankhwalawa pozindikira momwe ma phthalates amachepetsa mwayi wa mimba, chisokonezo ndi mahomoni oberekera ofunikira, kuphatikizapo zomwe zapezeka kale zomwe zimayambitsa kutupa ndi kupsinjika kwa okosijeni, malinga ndi zomwe zinasindikizidwa. ndi webusayiti ya New Atlas, kutchula za Environmental Health Perspectives. .

Sopo ndi kusamba thupi

Ma phthalates ndi gulu la mankhwala opangidwa ndi anthu omwe amagwiritsidwa ntchito kwambiri ngati zosungunulira, zopangira pulasitiki, ndi zokhazikika pazinthu zosamalira anthu monga sopo, kutsuka thupi, mafuta onunkhira, kupukuta misomali, shampu, gel osakaniza tsitsi, ndi tsitsi. Ma phthalates amapezekanso m'zinthu zina zomwe zimapezeka m'nyumba, monga vinyl pansi, mapulasitiki, mapaipi amaluwa, ndi zoseweretsa.

Idyani, imwani ndi kupuma mpweya

Malinga ndi bungwe la US Centers for Disease Control and Prevention (CDC), anthu amakumana ndi ma phthalates podya ndi kumwa zakudya zomwe zakhudzana ndi mankhwalawo, ndipo mawonekedwe ena amachitika pokoka tinthu tating'onoting'ono ta mpweya. Kafukufuku wasonyeza kuti kukhudzana ndi mitundu ina ya phthalates kumasokoneza dongosolo la endocrine ndikuwonjezera kutupa ndi kupsinjika kwa okosijeni.

Kafukufuku watsopano, wopangidwa ndi asayansi ku yunivesite ya Massachusetts, adawunika ubale womwe ulipo pakati pa kukhudzana ndi mimba isanayambe ku phthalates ndi mwayi wa amayi wokhala ndi pakati ndi kusunga mimba, ndi zotsatira zake pa kutupa ndi kupsinjika kwa okosijeni.

Endocrinology ndi kusanthula mkodzo

Carrie Nobles, wofufuza wamkulu wa kafukufukuyu anati: "Ma phthalates omwe amapezeka tsiku lililonse amasokoneza endocrine.
Ofufuzawa adasanthula zomwe adapeza ngati gawo la kafukufuku wokhudza zotsatira za aspirin pamimba ndi kubereka, zomwe zidatsata azimayi a 1288 pamiyeso isanu ndi umodzi ya msambo pomwe amayesa kutenga pakati ndikutsata amayi omwe adatenga pakati pa nthawi yonse yapakati. Avereji ya zaka za otenga nawo mbali inali zaka 28. Deta idasinthidwa malinga ndi zaka, kuchuluka kwa thupi, mtundu/ fuko, kusuta fodya, kufanana, kapena kuchuluka kwa nthawi yomwe mayiyo adabala mwana wosabadwayo yemwe ali ndi zaka zokwana masabata 24 kapena kupitilira apo.

mahomoni obereka

"Tinatha kuyang'ana zochitika zina zachilengedwe monga phthalates ndi momwe zimakhudzira nthawi yomwe imatengera kutenga pakati," adatero Nobles. Thupi likaphwanya ma phthalates, ma metabolites amachotsedwa mumkodzo. Ofufuzawo adasanthula ma metabolites 20 a phthalate ndi mahomoni oberekera m'mikodzo ya omwe adatenga nawo gawo ndikuyesa kuchuluka kwa mapuloteni a C-reactive mu seramu, chizindikiro cha kutupa.

phthalate metabolites

Kawirikawiri, mimba isanakwane mkodzo wambiri wa phthalate metabolites unagwirizanitsidwa ndi kuchepa kwa mimba mkati mwa nthawi imodzi ya msambo (kuthekera kwa chonde), kuphatikizapo 2-diethylhexyl-XNUMX, di-N-butyl, ndi benzyl-butyl metabolites. Koma panalibe mayanjano omveka bwino pakati pa phthalate metabolites ndi chiopsezo cha kutaya mimba.

Malinga ndi a Nobles, pali mitundu itatu yoyambirira ya phthalate yomwe "ikuwoneka kuti ikugwirizana kwambiri ndi kutenga nthawi yayitali kuti utenge pakati: DEHP, yomwe imapezeka muzinthu zapulasitiki za polyvinyl chloride monga zoseweretsa, zida za vinyl, makatani osambira, zomatira. , ndi ma CD ena chakudya, kuwonjezera Kwa mankhwala ndi zodzoladzola. DBP imapezekanso muzopaka tsitsi, kupukuta misomali, ndi mafuta onunkhira, pakati pa zinthu zina zapakhomo. BzBP imapezeka m'zikwama, malamba, ndi nsapato, komanso pang'ono pazinthu zina zosamalira anthu.

Low estradiol

Miyezo yambiri ya phthalate metabolites imagwirizanitsidwa ndi kuchepa kwa estradiol, hormone ya steroid yomwe imayang'anira msambo, panthawi ya msambo ndipo yakhala ikugwirizana ndi FSH ndi hormone ya luteinizing, yomwe imagwira ntchito limodzi kuti iwononge ovulation, zomwe zimagwira ntchito yofunika kwambiri pa mimba yoyambirira.

Nobles ananena kuti zizindikiro zimenezi “zimawonekeratu mwa amayi amene ali ndi vuto la kulephera kwa m’mimba, lomwe lingachitike ndi msinkhu komanso chifukwa cha zinthu zina.

Kutupa ndi kupsinjika kwa okosijeni

Ofufuzawa adapezanso kuti amayi omwe ali ndi ma phthalates ambiri amakhala ndi kutupa komanso kupsinjika kwa okosijeni, zomwe zimatha kuwononga ma cell ndi DNA ndikuyambitsa matenda. Ofufuza akuti kupezeka kulikonse kwa ma phthalates kumapangitsa kuti zikhale zovuta kwa amayi kuti aziwongolera mawonekedwe awo ngakhale atatenga njira zodzitetezera, monga kuyang'ana zolemba zomwe ogula amasankha ndikusankha zopanda phthalate, chifukwa amawapeza kudzera m'njira zingapo, kuphatikiza fumbi lochokera. Kuchokera ku zinthu zapakhomo, kuyamwa pakhungu la zinthu zosamalira munthu komanso zopaka misomali ndi mafuta onunkhiritsa, kupezeka m'zakudya chifukwa cha kulongedza zakudya, kuwonjezera pa kumeza chakudya choipitsidwa ndi madzi akumwa.

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