Kafukufuku watsopano komanso wodalirika wochizira odwala amtima

Kafukufuku watsopano komanso wodalirika wochizira odwala amtima

Ofufuza a ku Australia akwaniritsa zolinga ziwiri zoyambirira zomwe zingathandize kuyesetsa kwapadziko lonse kulimbana ndi matenda a mtima: ndiko, kupanga kugunda kwa mtima kakang'ono ndi kachitidwe kake ka mitsempha, ndipo chachiwiri kuti apeze momwe mitsempha ya mitsempha imakhudzira kuwonongeka kwa mtima chifukwa cha kutupa.

Mamiliyoni amafa chaka chilichonse

Malinga ndi webusaiti ya “New Atlas”, pogwira mawu magazini ya “Cell Reports,” matenda amtima ndi ena mwa omwe amayambitsa imfa padziko lonse lapansi.” Bungwe la World Health Organization “WHO” linanena kuti chaka chilichonse matenda a mtima ndi mtima amapha anthu pafupifupi 17.9 miliyoni. Matenda a mtima ndi amtima akuyembekezeka kukwera, chifukwa cha kukalamba kwa anthu komanso zovuta za moyo wawo.

Matenda a mtima

Matenda a mtima akuphatikizapo vuto lililonse lomwe limakhudza mtima kapena kufalikira kwa magazi, monga matenda a mtima, matenda a mitsempha, kuthamanga kwa magazi, sitiroko, ndi matenda a mtima. fufuzani matenda a gulu ili.

Zing'onozing'ono zomwe zimatsanzira mtima

Ofufuza a ku Australia apititsa patsogolo kafukufuku wokhudzana ndi matenda a mtima popanga organelles, nyumba zazing'ono zomwe zimatsanzira ziwalo za anthu, zomwe zimakula mu labotale pogwiritsa ntchito maselo amtundu wa pluripotent, omwe angapangidwe pogwiritsa ntchito "reprogrammed" khungu kapena maselo a magazi.

James Hudson, mmodzi wa ofufuza pa kafukufukuyu, anati: ‘Chiwalo chilichonse cha mtima n’chofanana ndi kukula kwa njere ya chia, mtunda wa mamilimita 1.5 okha, koma mkati mwake muli maselo 50000 oimira mitundu yosiyanasiyana ya maselo amene amapanga mtima. .

Kuchokera ku gulu la organelles ang'onoang'ono, ochita kafukufuku adapanga mtima wogunda, sitepe yokhayokha si yatsopano, koma ndi nthawi yoyamba kuti maselo a mitsempha, maselo omwe amayendetsa mitsempha ya magazi, akhoza kuphatikizidwa bwino, kubweretsa chitsanzo cha mtima pafupi. mtima weniweni wa munthu.

Hudson anati: "Kuphatikizira maselo a mitsempha kwa nthawi yoyamba mu minofu yaying'ono yamtima ndikofunika kwambiri chifukwa apezeka kuti ali ndi gawo lalikulu mu biology ya minofu, monga maselo a mitsempha amapangitsa kuti organelles azigwira ntchito bwino ndikumenya mwamphamvu, mu zomwe ziri zatsopano zomwe zimayambira. kudzakuthandizani kumvetsetsa bwino mtima.” kufotokoza molondola matendawo.

Kupeza kowonjezera

Bhonasi yowonjezera ya maselo a mitsempha imatanthauza kuti ochita kafukufuku amatha kufufuza momwe amakhudzira kutupa, zomwe zingayambitse matenda a atherosclerosis ndi kutupa kwa minofu ya mtima.

Ntchito yayikulu yama cell a mtima

Hudson anati: “Pamene kutupa kunkasonkhezeredwa m’timinofu tating’ono ta mtima, anapeza kuti maselo a mitsempha amagwira ntchito yaikulu.” Matenda a minyewa a m’mitsempha, omwe amakhala ndi maselo a mitsempha okha, anaonekera, kutanthauza kuti maselowo ankamva zimene zikuchitika n’kusintha. Kuti maselowa amatulutsa chinthu chotchedwa endothelin chomwe chimayambitsa matenda a sclerosis.”

Ofufuzawo akuti kutulukira kwina, kuphatikizapo kugwiritsa ntchito ma organoids atsopano a mtima, kungayambitse mankhwala atsopano a matenda a mtima mwamsanga.

Impso ndi matenda a ubongo

Kusindikiza kafukufukuyu, ofufuzawo akuti, zithandiza ofufuza padziko lonse lapansi kupanga ma organoids awo amagazi, kulimbikitsa kuyesetsa kwapadziko lonse kuthana ndi matenda amtima.

Maulosi a horoscope a Maguy Farah a chaka cha 2023