Kodi kukana milandu ozizira ndi ozizira?

Kodi kukana milandu ozizira ndi ozizira?

M'nyengo yozizira, mavairasi amayamba kufalikira ku dongosolo la kupuma, pamene zinthu zomwe zimalimbikitsa matenda pakati pawo zimatuluka, mwachitsanzo, kuchuluka kwa misonkhano mkati mwa malo otsekedwa kumene mavairasi amakhala bwino, popeza mpweya wamkati umauma. Koma sizinali zotsimikizika ngati kutentha kochepa kumafooketsa chitetezo cha mthupi cha munthu, ndipo ngati zili choncho, izi zimachitika bwanji.

Kafukufuku wofalitsidwa Lachiwiri mu Journal of Allergy and Clinical Immunology amafufuza njira yatsopano yomwe thupi limaukira ma virus ndikugwira ntchito bwino pakatentha.

Mansour Amiji, pulofesa ku Northeastern University, yemwe adalemba nawo kafukufukuyu, adauza AFP kuti zomwe apezazi zingathandize kupanga mankhwala atsopano a chimfine ndi ma virus ena.

Ntchito yofufuzayo idachokera ku kafukufuku wam'mbuyomu wopangidwa ndi Amiji mu 2018, omwe adapeza kuti ma cell am'mphuno amatulutsa ma vesicles amtundu wa extracellular, gulu la mamolekyu ang'onoang'ono omwe amaukira mabakiteriya pomwe mpweya umatuluka.

"Fanizo labwino kwambiri la njirayi ndi chisa cha manyanga," Ameji akutero. Mofanana ndi mavu amene amateteza chisa chawo pakachitika chiwembu, matumba amawulukira kunja kwa selo m’magulu, ndiyeno amamatira ku mabakiteriya ndi kuwapha.

Ofufuzawo adadzifunsa mafunso awiri: Kodi kutulutsa kwa ma vesicles owonjezera kumalembedwanso pamaso pa kachilomboka? Ndipo ngati ndi choncho, kodi kuyankha kwake kumakhudzidwa ndi kutentha?
M'mayesero awo, asayansi adagwiritsa ntchito mucous nembanemba ya mphuno za anthu odzipereka (omwe anali kuchitidwa opaleshoni kuchotsa ma polyps) ndi chinthu chomwe kachilombo ka HIV kamachulukira.
Zotsatira zake zinali kuchuluka kwa ma vesicles akunja omwe amatulutsidwa kuti awononge ma virus.

"Kutanthauzira Koyamba Kotsimikizika"

Kuti tiyankhe funso lachiwiri, mucous nembanemba wa mphuno anagawidwa m'magulu awiri, amene anali pansi chitukuko mu labotale, woyamba pa 37 digiri Celsius, pamene lachiwiri pa 32 digiri Celsius.

Kutentha kuwiriko kunasankhidwa potengera mayeso osonyeza kuti kutentha mkati mwa mphuno kumatsika pafupifupi 5°C pamene kunja kutentha kwa mpweya kumatsika kuchoka pa 23°C kufika pa 4°C.

Pansi pa kutentha kwa thupi, ma vesicles a extracellular amatha kulimbana ndi ma virus bwino, powapatsa "zonyengerera" zomwe ma virus amalowa, m'malo mwa ma cell receptors omwe nthawi zambiri amawalozera.

Koma ndi kutentha kochepa, ma vesicles ochepa amatulutsidwa kunja kwa selo ndipo sankagwira ntchito kwambiri ndi ma virus omwe adawayesa, omwe ndi mitundu iwiri ya ma rhinoviruses ndi coronavirus (non-Covid), yomwe imakhala yofala nthawi yachisanu.

Benjamin Blair, wolemba nawo za kafukufukuyu ndi dokotala wa opaleshoni pa Harvard Medical School, akuti, "Palibe chifukwa chotsimikizika chomwe chalembedwa chofotokozera momveka bwino kuchuluka kwa matenda obwera chifukwa cha ma virus m'miyezi yozizira," akumati zotsatira za kafukufukuyu zikuyimira " mafotokozedwe oyamba okhutiritsa okhudza kuchuluka kwa zinthu komanso zamoyo omwe akufikiridwa.” .

Mansour Ameji akuti zotsatira za kafukufukuyu zitha kupangitsa kuti pakhale chithandizo chamankhwala cholimbikitsa kupanga kwachilengedwe kwa ma extracellular vesicles, ndi cholinga chothana bwino ndi chimfine komanso chimfine komanso Covid-19, ndikuwonjezera kuti, "Dera ili la kafukufukuyu. kwambiri, ndipo tidzapitirizabe kutero.”