Peripheral neuropathy si matenda amodzi, kwenikweni ndi kuwonongeka kwa mitsempha chifukwa cha zinthu zingapo. Zifukwa za neuropathy ndi:

1- Matenda a shuga mellitus (diabetesic neuropathy).

2- Radical peripheral neuropathy chifukwa cha zovuta za msana ndi vertebrae.

3- Kuvulala kapena kupsinjika kwa mitsempha: Kuvulala, monga ngozi zagalimoto, kugwa kapena kuvulala kwamasewera, kumatha kudula kapena kuwononga mitsempha yotumphukira. Zitha kuchitika chifukwa cha kupanikizika kwa mitsempha ndi kuponyera, kugwiritsa ntchito ndodo, kapena kubwereza mayendedwe monga kulemba.

4- Kuperewera kwa Vitamini: Mavitamini a B (kuphatikizapo B-1, B-6, ndi B-12), vitamini D ndi niacin ndizofunikira kuti mitsempha ikhale yolimba.

5 - Hypothyroidism.

6- Mankhwala: Mankhwala ena, makamaka omwe amagwiritsidwa ntchito pochiza khansa (chemotherapy), angayambitse izi.

7. Matenda a autoimmune: Izi zikuphatikizapo Sjögren's syndrome, lupus, nyamakazi ya nyamakazi, Guillain-Barré syndrome, matenda a demyelinating polyneuritis ndi necrotizing vasculitis.

8- Kuledzera kwa mowa.

9- Kukumana ndi poizoni. Zinthu zapoizoni zimaphatikizapo zitsulo zolemera kapena mankhwala.

10- Infection: Izi zimaphatikizapo matenda ena a bakiteriya kapena ma virus kuphatikiza matenda a Lyme, herpes zoster (varicella zoster), kachilombo ka Epstein-Barr, hepatitis C, khate, diphtheria ndi HIV.

11- Matenda obadwa nawo. Matenda monga Charcot-Marie-Tooth ndi mitundu yobadwa nayo ya neuropathy.

12- Zotupa: Kukula kwa khansa (zoyipa) komanso kosakhala ndi khansa (zoyipa) kumatha kukhudza mitsempha yokha kapena kuonjezera kupanikizika kwa mitsempha yozungulira.

Polyneuropathy imathanso kubwera chifukwa cha mitundu ina ya khansa yokhudzana ndi chitetezo cha mthupi.

13- Matenda a mafupa a mafupa: myeloma chifukwa cha osteosclerosis, lymphoma, amyloidosis ndi ena.

14- Matenda ena: monga matenda a impso, matenda a chiwindi ...