Kuvimbisa kurapwa kwemajini kudzorera kunzwa kuvana matsi

Kuvimbisa kurapwa kwemajini kudzorera kunzwa kuvana matsi

Muedzo wekiriniki wepamusoro uchishandisa gene therapy wakadzoreredza kunzwa kuvana vashanu vakazvarwa vari matsi. Pashure pemwedzi mitanhatu, vana vacho vakanga vava kukwanisa kuziva kutaura uye kuita kurukurirano, vachimutsa tariro yokushandisa kwakawanda munguva pfupi iri kutevera, maererano nezvakabudiswa newebsite yeNew Atlas, ichitaura nezvemagazini inonzi Science Advances.

Kugara nhaka

Varwere vari mukutongwa vakatambura ne genetic condition inonzi autosomal recessive deafness 9 (DFNB9), iyo inokonzerwa nekuchinja kwejeni rinonzi OTOF, rinogadzira protein otoferlin, iyo inobatsira kuendesa mafungiro emagetsi kubva kucochlea kusvika kuuropi, kwaanogona. Kududzirwa senzwi - asi kana pasina. Zviratidzo izvi hazvimbosvikipo. Nekuti inokonzerwa nekuchinja kumwe chete uye haisanganisi kukuvadzwa kwemuviri kumaseru, timu inoti DFNB9 inokodzera mumiriri werudzi urwu rwegene therapy.

Muchidzidzo chakaitwa nevatsvakurudzi vekuHarvard Medical School, Massachusetts Eye and Ear, neFudan kuChina, kurapwa kwemajini kunosanganisira kurongedza jena reOTOF mumavhairasi anotakura uye kubaya musanganiswa wacho mumvura yemukati yenzeve. Mavhairasi aya akabva atsvaga masero mucochlea ndokuisa jena mavari, achivabvumira kuti vatange kugadzira puroteni yakarasika yeautoferlin uye kudzoreredza kunzwa.

Cochlear implant

Vana vatanhatu, vane makore ari pakati pegore rimwe kusvika manomwe, vane DFNB9 yakanga yavasiya vasinganzwe zvachose vakapindawo muchidzidzo ichi. Varwere vana vakaisirwa ma implants ecochlear, ayo akanzvenga chinetso chacho uye aigona kuvabvumira kudzidza kuziva kutaura nemimwe mitsindo. Muchiitiko ichi, kuisirwa kwakamiswa.

kuvandudzwa kunoshamisa

Mushure mekurapa kwemajini, vana vakateverwa kwemavhiki makumi maviri nematanhatu. Panguva iyoyo, vashanu pavatanhatu vakaratidza kuvandudzika kukuru, nevana vatatu vakura vachikwanisa kunzwisisa uye kupindura kutaura, nepo vaviri vakakwanisa kuitora muimba ine ruzha ndokuenderera mberi nekurukurirano parunhare. Vamwe vevana vacho vakanga vachiri vaduku zvikuru zvokusagona kupinda bvunzo dzenguva dzose, asi vakawanwa kuti vanodavira mitsindo, uye vakatotanga kutaura mashoko akapfava akadai sa“mama.” Kuvandudzwa kwacho kwakaitika zvishoma nezvishoma, asi boka racho rakashuma kuti vana vakatanga kuratidza migumisiro isati yaitwa bvunzo yekutanga mavhiki mana gare gare.

Genetic zvinokonzera uye kuchembera

Yilai Xu, muongorori mukuru weongororo iyi, akati vatori vechikamu muongororo iyi vacharamba vachitariswa, ukuwo zvidzidzo zvekutevera zvichiitwa kune vamwe vanhu. Chikwata ichi chinoti mvumo yekurapa muUnited States inogona kutora pakati pemakore matatu kusvika mashanu. Kufanana kwekurapa kwemajini kwakaedzwa kuti ione kutadza kunzwa kwemajini kana zera.

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