Mushonga wevarwere veasthma unoderedza zvinokuvadza

Mushonga wevarwere veasthma unoderedza zvinokuvadza

Kushandisa biologic therapy kuderedza kuzvimba kwemapapu kwakagonesa 92% yevanhu vane asthma yakanyanya kuderedza madosi avo emazuva ese einhaled steroid pasina kuwedzera zviratidzo zvavo, chidzidzo chitsva chakawana. Izvi zvakawanikwa zvinoreva kuti vanhu vane asthma yakaoma vanogona kuderedza njodzi yemigumisiro yakaipa inobatanidza nekushandisa kwenguva refu steroid, maererano neNew Atlas, ichitaura The Lancet.

Pavanhu vangangosvika mamirioni mazana matatu vane asthma pasi rose, vangangoita 300% kusvika 3% vane asima yakakomba, vachinzwa kutadza kufema kwemazuva ese, chipfuva uye kukosora izvo zvinowanzoendesa kuchipatara. Varwere vakanyanya kurwara neasthma vane subtype inodaidzwa kuti eosinophilic asthma, iyo inoratidzwa nehuwandu hwemasero ekudzivirira emuviri (eosinophils) muropa izvo zvinokonzera kuzvimba kusingadzoreki uye kuzvimba kwenzira dzemhepo.

Dzivisa migumisiro yakaipa inogona kuitika

Iyo inokurudzirwa kurapa eosinophilic asthma, maererano neGlobal Initiative yeAsthma (GINA), inosanganiswa yezuva nezuva yebudesonide (an inhaled corticosteroid yekugadzirisa kuzvimba) uye formoterol (yakareba-inobata bronchodilator yekuzorodza uye kuvhura nzira dzemhepo). Kurapa uku, kunozivikanwa se ICS kana "steroid," inofarirwa pane ipfupi-kuita "kununura" inhalers nekuda kweiyo mbiri anti-kuzvimba uye bronchodilator mhedzisiro. Asi kushandiswa kwenguva refu kunogona kuva dambudziko, sezvo ichibatanidzwa nemuromo thrush, osteoporosis, chirwere cheshuga, simba rekudzivirira muviri, uye cataracts.

Ongororo, yakaitwa nemasayendisiti kubva kuKing's College London kune varwere vari munyika ina: United Kingdom, France, Italy neGermany, yakaongorora kana kurapwa nebenralizumab (biological treatment) kunobvumira vanhu vane yakanyanya eosinophilic asthma kuderedza dosi yeICS pasina kurasikirwa. kudzora zviratidzo zvavo.

David Jackson, mutungamiri wechikwata chekutsvagisa, akati: "Kurapa kweBiological senge benralizumab kwakachinja zvakanyanya kutarisirwa asima munzira dzakawanda, uye mhedzisiro yechidzidzo chitsva inoratidza kekutanga kuti kukuvadza kune steroid kunogona kudzivirirwa kune vazhinji varwere vanoshandisa mushonga uyu.”

Benralizumab inopihwa nejekiseni rezasi kamwe chete mumavhiki mana ekutanga madosi matatu, uye kamwe chete mumavhiki masere.

Mhedzisiro yechidzidzo ichi yakaratidza kuti, kazhinji, 92% yevatori vechikamu vakaderedza chiyero cheICS. Kunyanya, 15% yavo yakaderedza dhigirii kusvika pachiyero chepakati, 17% kune yakaderera dosi, uye 61% kune imwe dosi sezvinodiwa chete. Zvakare, 91% yevatori vechikamu havana kuona kuwedzera kwezviratidzo panguva yekubata.

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