Nzira yekudzivisa sei nyaya dzekutonhora uye kutonhora?

Nzira yekudzivisa sei nyaya dzekutonhora uye kutonhora?

Nekusvika kwechando, mavhairasi anotanga kupararira kuhurongwa hwekufema, nepo zvinhu zvinokurudzira hutachiona pakati pavo zvinobuda, semuenzaniso, huwandu hukuru hwekuungana mukati menzvimbo dzakavharwa umo mavhairasi anogara zviri nani, sezvo mhepo yemukati yakaoma. Asi zvaisave nechokwadi kana tembiricha yakaderera ichinetesa immune system yemunhu, uye kana zviri izvo, izvi zvinoitwa sei.

Chidzidzo chakaburitswa neChipiri muJournal yeAllergy uye Clinical Immunology inoongorora nzira itsva iyo muviri inorwisa mavhairasi uye inoshanda zvirinani kana kuchidziya.

Mansour Amiji, purofesa kuNortheastern University, uyo akanyora chidzidzo ichi, akaudza AFP kuti zvakawanikwa izvi zvinogona kubatsira kugadzira mishonga mitsva yedzihwa nehumwe hutachiona.

Basa rekutsvagisa rakatanga kubva paongororo yapfuura yakaitwa naAmiji muna 2018, iyo yakawana kuti masero emhino anoburitsa extracellular vesicles, boka remamorekuru madiki anorwisa mabhakitiriya kana mweya wafemerwa.

“Muenzaniso wakanakisisa wekuita uku idendere rehornet,” anodaro Ameji. Semavu anodzivirira dendere rawo kana arwiswa, masaga anobhururuka achibuda musero ari mumapoka, obva anamatira kubhakitiriya ovauraya.

Vatsvagiri vakazvibvunza mibvunzo miviri: Ko kuvharwa kweextracellular vesicles zvakare kunyorwa pamberi pehutachiona here? Uye kana zvakadaro, mhinduro yaro inokanganiswa netembiricha here?
Mukuedza kwavo, masayendisiti akashandisa mucous membrane yemhino dzevazvipiri (avo vakanga vachivhiyiwa kuti vabvise polyps) uye chinhu umo hutachiona hwehutachiona hunowedzera.
Mhedzisiro yaive nhamba yakanaka yeextracellular vesicles yakavanzwa kurwisa mavhairasi.

"Dudziro Yokutanga Inogutsa"

Kuti apindure mubvunzo wechipiri, mucous membranes yemhino yakakamurwa kuita mapoka maviri, ayo akaiswa pasi pekuvandudzwa murabhoritari, yekutanga pa37 degrees Celsius, nepo yechipiri pa32 degrees Celsius.

Tembiricha mbiri idzi dzakasarudzwa zvichibva pabvunzo dzinoratidza kuti tembiricha yemukati memhino inodonha neinosvika 5°C kana tembiricha yekunze ichidzika kubva pa23°C kusvika pa4°C.

Pasi pemamiriro ekupisa kwemuviri, iwo maextracellular vesicles akakwanisa kurwisa mavhairasi zvakanaka, nekuvapa "decoys" iyo mavhairasi anobatirira, pane maseru receptors avaiwanzo tarisa.

Asi nekudzikira kwetembiricha, mavhesi mashoma akavharirwa kunze kwesero uye akange asingashande kurwisa hutachiona hwavakaedza, ari marudzi maviri erhinoviruses uye coronavirus (isina-Covid), inowanzoitika munguva yechando.

Benjamin Blair, munyori pamwe chete wekudzidza uye chiremba wokuvhiya paHarvard Medical School, anoti, "Hapana chikonzero chinogutsa chakanyorwa kuti chitsanangure kuwedzera kwakajeka kwehutachiona hwehutachiona mukati memwedzi inotonhora," achicherechedza kuti mhedzisiro yeongororo inomiririra " yekutanga inogutsa tsananguro yehuwandu uye yebiology iri kuwanikwa." .

Mansour Ameji anocherekedza kuti mhedzisiro yechidzidzo ichi inogona kutungamira mukuvandudzwa kwemishonga yekukurudzira kugadzirwa kwechisikigo cheextracellular vesicles, nechinangwa chekurwisa zviri nani kutonhora uye kunyange furuwenza uye Covid-19, achiwedzera, "Nzvimbo iyi yezvido zvetsvagiridzo. isu zvikuru, uye ticharamba tichishanda pazviri.”