Ndechipi chinobatana pakati pezvirwere zvekugaya uye uropi?

Ndechipi chinobatana pakati pezvirwere zvekugaya uye uropi?

Zvidzidzo zvenguva ichangopfuura zvemhuka zvakaratidza kuti chirwere cheAlzheimer chinogona kutapurirwa kumakonzo madiki kuburikidza nekufambiswa kwegut microbes, zvichisimbisa hukama pakati pechikafu chekudya uye hutano hwehuropi, maererano nezvakadhindwa neSainzi Alert webhusaiti, ichitaura mumagazini Scientific Reports.

Negative mhedzisiro yekuzvimba

Ongororo itsva inowedzera tsigiro kudzidziso yokuti kuzvimba kunogona kuita kuti kunokanganisa utano hwehuropi.” “Zvakaonekwa kuti vanhu vane chirwere cheAlzheimer vanonyanya kuzvimba muura,” anodaro chiremba wepfungwa Barbara Bendlin weUniversity of. Wisconsin. "Kufungidzira kweuropi, avo vane kuzvimba kwakanyanya muura vaive nemwero wakakwirira weamyloid [protein clumps] buildup muuropi hwavo."

Calprotectin test

Margo Heston, chiremba wezvirwere paYunivhesiti yeWisconsin, uye boka renyika dzakawanda revatsvakurudzi vakaedza fecal calprotectin, chiratidzo chekuzvimba, mumasampuli ezvituru kubva kuvanhu 125 vakasarudzwa kubva muzvidzidzo zviviri zvekudzivirira chirwere cheAlzheimer. Vatori vechikamu vakaita bvunzo dzakati wandei pavakanyoreswa muchidzidzo, mukuwedzera kubvunzurudzo dzenhoroondo yemhuri uye bvunzo dzemhando yepamusoro yeAlzheimer's. A subset yakaitwa kuongororwa kwekiriniki yezviratidzo zveamyloid protein clumps, chiratidzo chakajairika chechirwere chinokonzera neurodegenerative mamiriro. Kunyange zvazvo calprotectin mazinga aiwanzove akakwirira muvarwere vakwegura, ainyanya kutaurwa kune avo vane amyloid plaques yechirwere cheAlzheimer.

Alzheimer's kana kuderera ndangariro

Malenho emamwe ma biomarker echirwere cheAlzheimer akawedzerawo nemazinga ekuzvimba, uye ndangariro bvunzo dzadzikira sezvo calprotectin yakasimukawo. Kunyange vatori vechikamu vasina kuonekwa kuti vane chirwere cheAlzheimer vaiva nemafungiro asina kunaka ane mazinga akakwirira ecalprotectin.

Kuchinja kwemabhakitiriya emudumbu

Ongororo yerabhoritari yakamboratidza kuti makemikari anobva mumatumbo mabhakitiriya anogona kukurudzira zviratidzo zvekuzvimba muuropi. Zvimwe zvidzidzo zvakawanawo kuwedzera kwekuzvimba kwematumbo muvarwere veAlzheimer zvichienzaniswa neboka rekutonga.
Heston nevamwe vake vanoratidza kuti shanduko muiyo microbiome inotungamira kune shanduko muura inotungamira mukuzvimba padanho rehurongwa. Kuzvimba uku kwakapfava asi kusingaperi, uye kunokonzera kukuvadzwa kusinganzwisisike uye kunofambira mberi kunozokanganisa kunzwisiswa kwezvipingamupinyi zvemuviri.

Ropa-uropi chipingamupinyi

"Kuwedzera kwemukati memudumbu kunogona kutungamirira kumazinga akakwirira ekuputira mamorekuru uye chepfu inotorwa kubva mumatumbo lumen muropa, zvichiita kuti systemic kuzvimba, izvo zvinogona kuderedza simba reropa-uropi uye zvinogona kukurudzira kuzvimba," anodaro Federico Re, purofesa. of bacteriology paWisconsin State University. nerves, [zvichikonzera] kukuvara kwetsinga uye neurodegeneration.

Kuchinja kwekudya

Vatsvagiri parizvino vari kuyedza nembeva dzemurabhoritari kuti vaone kana shanduko yekudya ine chekuita nekuwedzera kuzvimba inogona kukonzeresa vhezheni yechirwere cheAlzheimer mumakonzo.
Pasinei nemakumi emakore ekutsvagisa, hapasati pasisina kurapwa kunoshanda kwemamiriyoni evanhu vane chirwere cheAlzheimer pasi rose. Asi nekunzwisisa kukuru kwemaitiro ezvipenyu, masayendisiti ari kuswedera pedyo nekuswedera.

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