Mushonga unovimbisa kune avo vanotambura nemarwadzo emusana

Mushonga unovimbisa kune avo vanotambura nemarwadzo emusana

Masayendisiti paCedars-Sinai Medical Center akacherechedza chidimbu chitsva chemasero mukati mekuderera, jelly-like intervertebral discs muvanhu vane kurwadziwa kwepashure. Aya maseru haaoneki muvanhu vane hutano intervertebral discs kana madhisiki akaora vasina kurwadziwa, maererano neNew Atlas, ichitaura nezvemagazini inonzi Science Translational Medicine.

Masero ari kumashure vertebrae

Mutungamiriri wemuongorori Dr. Dmitry Shein, musayendisiti anotsvakurudza paCedars-Sinai Center, akati iye neboka rake rekutsvakurudza vakabudirira mu "kuziva kekutanga masero chaiwo anogona kuva kiyi yekunzwisisa marwadzo" mumusana wemusana, achicherechedza kuti "Kuziva zvakawanda nezvemashandiro anoita masero aya kunogona kutungamirira ku... "Pakupedzisira kuwana nzira itsva dzekurapa."

Muchidzidzo ichi, vatsvakurudzi vakafananidza kuderera kwemamiriro ezvinhu mu vertebrae uye vakashandura masero ane tsika kuva iyi ichangobva kuwanikwa ine marwadzo ane chokuita nesero subtype. Vatsvakurudzi vakagadzirawo masero mune imwe kamuri yemakamuri maviri emakamuri. Mune imwe kamuri, vakaisa marwadzo-anonongedza neurons ayo akagadzirwa kubva kumaseru.

Marwadzo masero

Vatsvagiri vakaona kuti kana maseru ane chekuita nemarwadzo aivepo muchidimbu, neurons mukamuri yechipiri akakura maaxon - iyo fibrous network iyo masaini anofambiswa - munzira yemarwadzo maseru. Asi pakanga pasina shanduko mukuumbwa kwemaneuroni apo masero ane hutano aive mukamuri rinotevera.

Dr. Shen vakati zvakanga zvisati zvazivikanwa "kana masero anokonzerwa nemarwadzo akakwezva neuroni dzinopinda, kana kuti masero ane utano akaidzinga, asi pakanga pane mutsauko pakati pemasero ane utano uye masero anokonzerwa nemarwadzo."

Kupinda mumagumo etsinga

Nekuda kwekuti hapana magumo etsinga mu intervertebral discs, kuparara kwavo hakurevi hazvo kutungamirira kumarwadzo ekumusana. Asi kana masimbi emuzongoza akapera nekuoma, matishu akaapoteredza anogona kukanganisa.

"Dzimwe nguva, kana ma discs apera, magumo etsinga kubva mumucheka wakapoteredza anopinda mu disc, [iyo inogona kuva chikonzero chekunzwa] kurwadziwa," Dr. Shen akatsanangura.

Kuwana kunonakidza

Kuwanikwa kwacho kunonakidza sezvo kuchigona kutungamira kune zvakakosha nzira dzekurapa kune vangangoita 40% yevakuru vanotambura nekurwadziwa kwemusana nekuda kwekuderera kwe vertebrae.

Vatsvakurudzi vanofungidzira kuti nzira dzokurapa dzinogona kusanganisira kugadzirisa masero ane chokuita nemarwadzo kana kuzadza ma discs nemasero ane hutano kuti akunde matambudziko ose.

"Kunyanya kutarisa 'yakaipa' cell subtype kana kuzadzisa 'yakanaka' cell subtype inogona kupa mazano anobatsira ekurapa vertebra-based low back pain," akadaro Clive Svendsen weCedars-Sinai, achiona kuti "migumisiro yekudzidza inoratidza chokwadi che" Rumwe ruzivo rweclassical spine kana pain biology inogona kuve nhanho yakanangana nesero therapy inogadzirisa izvo zvinokonzeresa kurwadziwa kwemusana. "

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