Zvidzidzo zvezvino, kurapa kunoshanda kwechirwere cheshuga

Zvinoita sekuti dambudziko risingagadziriswe iri richapera munguva pfupi iri kutevera, sezvo vatsvakurudzi veJapan vakazivisa kuwanikwa kwemaitiro matsva anoenderana nekugadzirisa mashandiro e enzyme muchiropa, izvo zvinogona kutungamira kurapwa kunobudirira kwechirwere cheshuga cherudzi rwechipiri.
Chidzidzo ichi chakaitwa nevaongorori vepaKanazawa University kuJapan, uye mhedzisiro yavo yakaburitswa mupepanhau resainzi Nature Communications.

Dare rekutsvakurudza rakaita chidzidzo cheboka remakonzo mukuedza kunzwisisa nzira yemamiriro ehuga hwepamusoro mushure mekudya.
Chikwata ichi chakawedzera kuti chirwere ichi chinowanzokonzerwa nekusagadzikana mukutorwa kweglucose nechiropa, uye kunobata varwere vane Type II chirwere cheshuga uye kufutisa, uye zvinotungamira mungozi yekuwedzera yezvirwere zvemoyo.
Kunyange zvazvo nzira iri shure kwekukanganiswa kweglucose yeropa haisati yazivikanwa, pane uchapupu hwokuti inokonzerwa nekuvhiringidza muhepatic glucokinase enzyme.
Uye glucokinase imwe ye enzymes yechiropa, iyo inokurumidza uye inobatsira nzira yekushandura glucose mu "glucose-6-phosphate", iyo ndiyo yekutanga danho re glycolysis.
Muchidzidzo chavo chitsva, vaongorori vakakwanisa kuona enzyme inonzi Sirt2 inoita basa rakakosha mukugadzirisa mashandiro ehepatic glucokinase nekugadzirisa kusaenzana mukutorwa kweglucose nechiropa.
Vatsvagiri vakati kunzwisisa mashandiro aya uye kudzora mashandiro e enzyme iyi kunogona kumiririra chinangwa chekurapa chinoshanda cherudzi rweXNUMX chirwere cheshuga uye kufutisa.
Vakawedzera kuti vakacherekedza kuti mbeva dzine chirwere cheshuga cherudzi rwechipiri zvakare dzakafuta, uye kuti kurapwa kwekusagadzikana kwekutorwa kweglucose yechiropa kunogona kumisa kukwira kweshuga yeropa mushure mekudya.
Maererano neWorld Health Organization, inenge 90% yezviitiko zvakanyoreswa zvechirwere cheshuga munyika yose ndeye XNUMX, iyo inoratidzika zvakanyanya nekuda kwekunyanya kuwandisa uye kusaita basa rekuita, uye nekufamba kwenguva, huwandu hweshuga muropa hunogona kuwedzera. njodzi yechirwere chemoyo.upofu, tsinga uye kusashanda zvakanaka kweitsvo.
Kusiyana neizvi, chirwere cheshuga chorudzi rwokutanga chinoitika apo simba romuviri rokuzvidzivirira pazvirwere zvinoparadza masero anodzora uwandu hweshuga muropa, zvikurukuru muvana.

Sangano iri rakaratidza kuti vanhu 422 miriyoni pasi rose vanorwara nechirwere cheshuga, uye Eastern Mediterranean Region ine chikamu chevanhu mamiriyoni makumi mana nematatu.