Hal-abuur cilmiyeed oo lagu daweynayo cudurrada wadnaha

Hal-abuur cilmiyeed oo lagu daweynayo cudurrada wadnaha

Cilmi-baaris cusub oo cusub, saynisyahannadu waxay dib u qori doonaan DNA iyaga oo ujeedadu tahay in la helo daaweynta ugu horreysa ee adduunka ee cudurrada wadnaha hiddaha, taas oo lagu tilmaami karo "daqiiqad go'aan" oo ku saabsan daawada wadnaha.

Sida laga soo xigtay waxa lagu daabacay bogga "Boldsky", saynisyahano caalami ah oo ka socda Boqortooyada Ingiriiska, Maraykanka iyo Singapore ayaa iska kaashaday mashruuca "Cure Heart" si loogu naqshadeeyo tallaalka bukaanka wadnaha. Sida ay sheegayaan wararka, Hay’adda Wadnaha ee Britain ayaa ku yaboohday 30 milyan oo Yuuro mashruucan lagu badbaadinayo nolosha.

Marka ugu horeysa, cilmi-baarayaashu waxay isticmaali doonaan farsamooyin hidde ah oo sax ah, oo loo yaqaano isbeddelka aasaasiga ah, ee wadnaha si ay u naqshadeeyaan oo ay u tijaabiyaan daaweynta ugu horreysa ee cudurrada murqaha wadnaha ee la iska dhaxlo, iyada oo ujeedadu tahay in la carqaladeeyo hiddo-wadaha khaldan.

Wadna xanuunka laga dhaxlo

“Wadnaha la iska dhaxlo” waa eray ay ku jiraan dhammaan cudurrada wadnaha ee ay waalidiintu u gudbiyaan ubadkooda, tusaale ahaan marka mid ama labada waalid ay leeyihiin hidde-side cilladaysan ama is-beddelay, waxaa jirta fursad 50/50 ah oo ay u gudbin karaan carruurta. Qaar ka mid ah cudurrada wadnaha ee la dhaxlo waxaa ka mid ah hypertrophic cardiomyopathy iyo hypercholesterolemia.

Dadka qaar ee qaba cudurrada wadnaha ee la iska dhaxlo waxaa laga yaabaa in aysan yeelan calaamado badan, xaaladdana lama ogaan karo ilaa ay ka dambeeyaan wadno-qabad degdeg ah, suuxdin, ama geeri degdeg ah. Tirakoobyadu waxay muujinayaan in qiyaastii 0.8 ilaa 1.2% dhallaanka cusub ee adduunka oo dhan ay saameeyeen cudurrada wadnaha ee hidde-sideyaasha.

Fursad taariikhi ah iyo 30 sano oo cilmi baaris ah

Guddi la-talin ah oo uu madax u yahay Professor Sir Patrick Vallance, oo ah madaxa lataliyaha sayniska ee dawladda Ingiriiska, ayaa doortay kooxda mas'uulka ka ah daraasaddan muhiimka ah, halka Professor Hugh Watkins, oo ka tirsan Jaamacadda Oxford iyo baaraha maamulaha ee mashruuca Wadnaha lagu daweeyo, uu sheegay in wadnaha wadnaha. Waa cudur halis ah.Runtii waa xaalad “caadi ah” adduunka oo dhan waxaana la og yahay inay saameyso 250 qof XNUMX qofba.

Professor Watkins ayaa intaa ku daray, isaga oo ku tilmaamay daraasadda inay tahay "fursad hal-mar ah oo jiilka ah" oo looga golleeyahay in lagu yareeyo welwelka joogtada ah ee ku saabsan dhimashada degdega ah, wadnaha oo aan shaqeynin iyo baahida suurtagalka ah ee loogu talagalay beerista wadnaha.

Professor Watkins ayaa sharaxay, "Kadib 30 sano oo cilmi baaris ah, hiddo-sideyaal badan oo gaar ah iyo cillado hidde-side ah ayaa la ogaaday kuwaas oo ka mas'uul ah wadna xanuunka kala duwan iyo sida ay u shaqeeyaan. Waxa la rumaysan yahay in ay jiri doonto daawaynta hidda-sidaha oo la heli karo si loo bilaabo tijaabooyinka caafimaad iyo tijaabooyin shanta sano ee soo socota gudahooda.”

Saxitaanka hiddo-wadaha cilladaysan

Waxaa la rajeynayaa in barnaamijka cusub ee cilmi-baarista uu si joogto ah u saxo isbeddellada hidde-sideyaasha ee ka masuulka ah dhibaatooyinka wadnaha.

Xaaladdan oo kale, Christine Seidman, oo ah borofisar wax ka dhiga Dugsiga Caafimaadka ee Harvard iyo cilmi-baadhaha hormuudka ka ah mashruuca, ayaa sharraxay in ujeedadu ahayd "in la dayactiro wadnaha" oo dib loo soo celiyo shaqadooda caadiga ah, iyada oo sharraxaysa "inta badan isbeddellada ka dhex muuqda bukaannada ayaa hoggaamiya. In hal xaraf loo beddelo si isdaba joog ah, laga soo bilaabo koodhka DNA-da, taas oo macnaheedu yahay in uu jiro daawo iyadoo la beddelayo monogramka oo dib loo soo celinayo koodka.

Sida laga soo xigtay cilmi-baarayaasha, hor-u-yaal ka kala yimid saddex qaaradood oo lagu kala soocay dhinaca tafatirka hidda-socodka cusub iyo aadka saxda ah ee ku lug leh cilmi-baarista, tijaabooyinka bini'aadamka ayaan wali la sameynin, laakiin tijaabooyinka xayawaanka ayaa lagu guuleystay oo rajo leh.

Cilmi-baadhayaashu waxay intaa ku dareen in la rajaynayo in dadka khatarta ugu jira inay ku dhacaan cudurrada wadnaha ee hidde-sideyaasha sababtoo ah jiritaanka hidde-sideyaasha cilladaysan ee qoysaskooda ay awoodaan inay helaan daaweyn ka hor inta uusan cudurkoodu soo bixin.