Sigaarku maaha waxa kaliya ee ugu weyn ee kansarka sanbabada

Sigaarku maaha waxa kaliya ee ugu weyn ee kansarka sanbabada

Qaar ka mid ah wasakhowga hawada ayaa u muuqda sida "dilaaga qarsoon", sababtoo ah waxay sababi karaan tiro kansarka sanbabada ah dadka aan sigaarka cabbin, iyada oo loo marayo hab lagu sharraxay daraasad la daabacay Sabtidii, iyo in la gaaro fahamkooda waa "tallaabo muhiim u ah sayniska iyo bulshada,” sida laga soo xigtay koox khubaro ah.

Saynis yahano ka socda machadka Francis Crick iyo University College London ayaa sharaxay in qaybo yaryar (in ka yar 2,5 microns, qiyaastii dhexroorka timaha), kuwaas oo loo tixgaliyo inay ka mid yihiin sababaha isbeddelka cimilada, ay keenaan isbeddelo kansar ah oo ku yimaada unugyada hab-dhiska neefsiga.

dilaaga qarsoodiga ah

Qaybaha qafiifka ah ee ku jira gaaska qiiqa, boodhka biriiga ama qiiqa ka soo baxa shidaalka fosil ayaa la mid noqon kara " dilaa qarsoon ", ayuu yidhi Charles Swanton oo ka tirsan machadka Francis Crick, oo soo bandhigay natiijada cilmi-baadhistan, oo aanay wali dib u eegin cilmi-baarayaal kale. Inta lagu guda jiro shirka sanadlaha ah ee Bulshada Yurub ee Oncology Medical, lagu qabtay Paris ilaa 13 Sebtembar.

Inkastoo Professor Swanton uu xasuusiyay in waxyeelada wasakhowga hawada la ogaa muddo dheer, wuxuu xusay in saynisyahannadu "aysan hubin in wasakhowgani uu si toos ah u keeno kansarka sanbabada."

Cilmi-baadhayaashu waxay markii ugu horreysay daraasad ku sameeyeen xogta in ka badan 460 oo qof oo ka kala yimid England, South Korea iyo Taiwan, waxayna muujiyeen xiriirka ka dhexeeya soo-gaadhista korodhka uruurinta walxaha ganaaxa iyo khatarta sii kordheysa ee kansarka sanbabada.

250 muunado

Si kastaba ha ahaatee, daah-furka ugu caansan ayaa ah fahamka habka ay wasakhowgani u keenaan kansarka sanbabada ee aan sigaarka cabbin.

Daraasadaha shaybaarka ee jiirarka, cilmi-baarayaashu waxay muujiyeen in qaybo ka mid ah ay keeneen isbeddel ku yimid laba hidde-side, kuwaas oo ah epidermal growth factor reseptor (EGFR) iyo Keras (KRAS), kuwaas oo horeyba ugu xiran kansarka sanbabada.

Kadibna cilmi-baarayaashu waxay falanqeeyeen ilaa 250 muunado oo ah unug sambabada oo caafimaad qaba oo aan waligood la kulmin kansarka tubaakada ama wasakhowga culus. Isbeddellada ku jira hidda-wadaha EGFR ayaa ka soo muuqday 18 boqolkiiba shaybaarrada, iyo isbeddellada KRAS ee 33 boqolkiiba.

"qarsoodi"

Prof Swanton ayaa sheegay in "isbeddelladan laga yaabo inaysan ku filneyn naftooda inay u horseedaan kansar, laakiin marka unugga uu soo gaaro wasakh, waxay u badan tahay inay kiciyaan nooc ka mid ah falcelinta" bararka. Waxa uu intaa ku daray in "unuggu uu soo saari doono kansar" haddii uu "isku bedelo."

Swanton, oo madax ka ah kafaala-qaadka ugu weyn ee daraasaddan, Cancer Research UK, ayaa sheegay in daraasaddu ay tahay "dejinta habka bayoolojiga ee waxa qarsoon."

Waxaa la aaminsanaa in soo-gaadhista walxaha kansarka sababa, sida kuwa ka dhasha qiiqa sigaarka ama wasakhowga, ay sababto isbeddellada hidde-sideyaasha ee unugyada, taasoo ka dhigaysa burooyin una horseedda inay bataan.

Agaasimaha Barnaamijka Ka Hortagga Kansarka ee Machadka Gustave Rossi Sozette Delalog ayaa xusay in natiijooyinka cilmi-baaristu ay yihiin "horumar kacaan", "ma jirin caddayn hore oo ah kansarkan beddelka ah."

Kansarka Kansarka, oo loo xilsaaray inuu ka hadlo daraasadda inta lagu guda jiro shirka, ayaa ku nuuxnuuxsaday inay tahay "tallaabo muhiim u ah sayniska", isagoo rajeynaya inay sidaas oo kale u noqon doonto "bulshada sidoo kale", oo loo tixgeliyey inay "fureyso albaab ballaaran oo aqoonta laakiin sidoo kale ka hortagga."

Yaraynta wasakhowga hawada

Prof Swanton wuxuu sheegay in tallaabada xigta ay noqon doonto "in la fahmo sababta qaar ka mid ah unugyada sambabada ee isbedelay ay isu beddelaan kansar ka dib markii ay la kulmaan wasakhowga".

Tiro cilmi-baarayaal ah ayaa iftiimiyay in daraasaddan ay xaqiijinayso in yaraynta wasakhowga hawada ay sidoo kale muhiim u tahay caafimaadka.

"Waxaan leenahay ikhtiyaar u dhexeeya sigaar cabista iyo in kale, laakiin ma dooran karno hawada aan neefsaneyno," Swanton ayaa sidaas yidhi. Markaa waa dhibaato caalami ah marka la eego in tirada dadka soo gaadhay heerar wasakhaysan oo caafimaad darro ah ay u badan tahay inay shan jeer ka badan yihiin kuwa qiiqa tubaakada.

In ka badan 90 boqolkiiba dadka adduunka ayaa la kulmay waxa Ururka Caafimaadka Adduunka ku tilmaamay heerar xad-dhaaf ah oo wasakhaysan oo ay ku jiraan walxo yaryar.