Daraasad rajo leh oo ku saabsan daaweynta cudurka Parkinson

Daraasad rajo leh oo ku saabsan daaweynta cudurka Parkinson

In ka badan 10 milyan oo qof oo adduunka ah ayaa la nool cudurka PD ama Parkinson. Waa xanuun aan la daweyn karin oo neerfayaasha ah oo lagu garto gariir, murqaha oo adkaada, dhaqdhaqaaqa daciifka ah, iyo dheelitirnaanta iyo iskudubarid liidata.

Si kastaba ha ahaatee, daraasad cusub ayaa ogaatay in nooc ka mid ah bakteeriyada mindhicirku ay keento 'burburka' neerfaha kuwaas oo calaamad u ah cudurka Parkinson.

Iyadoo daahfurkaani uu albaabka u furayo horumarinta daawaynta la beegsanayo ee cudurkan daciifka ah, marka loo eego waxa New Atlas ka sheegay Frontiers in Cellular and Infection Microbiology journal.

alfa-synuclein protein

Marka borotiinka alfa-synuclein, oo inta badan laga helo unugyada dareemayaasha, uu ururo, wuxuu sameeyaa jirka Lewy. Joogitaanka alfa-synuclein iyo jirka Lewy ee maskaxda iyo guud ahaan habdhiska dareenka waa calaamad lagu garto cudurka Parkinson.

Isku darka alfa syncytia ayaa sidoo kale laga helay mindhicirka, waxaana loo maleynayaa in cudur-sidaha ku salaysan mindhicirka uu keeni karo isugeyn, ka dibna u socdaalaya maskaxda.

ka caan ah

Dadaal lagu doonayo in si wanaagsan loo fahmo sababaha cudurka Parkinson, cilmi-baarayaal ka socda Jaamacadda Helsinki ee Finland waxay baareen doorka ay ciyaari karto nooc ka mid ah bakteeriyada, gaar ahaan Desulfovibrio, oo loo yaqaan DSV.

Waxaa xusid mudan in xiriirka ka dhexeeya bakteeriyada Desulfovibrio ee waxyeelada leh iyo cudurka Parkinson la baaray 2021. Waqtigaas, cilmi-baarayaashu waxay ogaadeen in bakteeriyada ay aad ugu badan tahay bukaannada Parkinson. Waxay ogaadeen in ay jiraan calaamado darran oo lagu arkay bukaanada lahaa kor u kaca bakteeriyada DSV.

noocyada gaarka ah

Si kastaba ha ahaatee, daraasad 2021, laguma sahamin sida bakteeriyada DSV ay gacan uga geysato horumarinta cudurka Parkinson. Marka, gudaha Caenorhabditis elegans, cilmi-baarayaashu waxay dejiyeen inay baaraan bal in noocyada DSV ay gacan ka geystaan ​​ururinta jirka alfa-synuclein iyo sidaas darteed cudurka Parkinson.

Waxayna ku soo gabagabeeyeen, tijaabooyinkooda shaybaadhka ka dib, in noocyada bakteeriyada DSV ee ka timaada dadka qaba cudurka Parkinson, oo ka duwan dadka caafimaadka qaba, ay u muuqdaan inay aad u sun badan yihiin waxayna sababi karaan ururo badan oo alfa-synuclein ah, taas oo muujinaysa in natiijada daraasaddu ay muujinayso muhiim. doorka ay arrimaha deegaanka ka ciyaaraan horumarinta caabuqa. Cudurka Parkinson.

Natiijooyin muhiim ah

Marka la eego macnaha guud, Per Saris, oo ka mid ah qoraaga daraasadda, ayaa yiri, "Natiijooyinkayagu waa muhiim, sababtoo ah sababta cudurka Parkinson weli lama garanayo inkastoo la isku dayey in la aqoonsado labadii qarni ee la soo dhaafay."

Waxa uu intaa ku daray, "Natiijooyinka waxay muujinayaan in noocyada bakteeriyada Desulfovibrio ay u badan tahay inay keenaan cudurka Parkinson, taas oo ah, inta badan waxaa sababa arrimo deegaanka," isaga oo sharxaya in "soo-gaadhista deegaanka ee noocyada bakteeriyada DSV ay keento cudurka Parkinson," isagoo xusay in "Parkinson's cudurku waxa uu keenaa Boqolkiiba yar, ama ku dhawaad ​​10%, ee hiddo-wadaha waa shaqsi.

Ka takhalusidda bakteeriyada waxyeelada leh

Waxa kale oo uu sharraxay, marka la eego natiijooyinka daraasadda, "sidayaasha bakteeriyada waxyeellada leh waxaa laga ogaan karaa Desulfovibrio. Markaa, waxaa lagu beegsan karaa habraacyo looga saarayo noocyadan mindhicirka, kuwaas oo laga yaabo inay yareeyaan oo ay yareeyaan calaamadaha cudurka Parkinson.

Waxaa la tilmaamay in daraasado kale oo mustaqbalka ah ay muujin karaan faraqa u dhexeeya noocyada Desulfovibrio DSV, kuwaas oo lagu arkay dadka qaba curyaanka maskaxda iyo maadooyinka caafimaadka qaba.

Maguy Farah saadaasha horoscope ee sanadka 2023