اTšebeliso ea likhetla tsa mahe ho phekola lefu la ho fokola ha masapo

Tšebeliso ea likhetla tsa mahe ho phekola lefu la ho fokola ha masapo

Likhetla tsa mahe tse sa batleheng li bonahala e le thepa ea bohlokoa bakeng sa ho etsa li- grafts tsa masapo tse sireletsehileng le tse sebetsang bakeng sa batho, ho ea ka New Atlas, e qotsa koranta ea Smart Materials in Medicine.

E le ho theha boitsebiso bo bocha bakeng sa ho khomarela masapo a sireletsehileng le a sebetsang hantle, bafuputsi ba ile ba sebelisa likhetla tsa mahe a likhoho, tse fumanehang hohle le tse theko e tlaase.

Bafuputsi ba thehile mokhoa o mocha oa ho qhibiliha le pula ho etsa likaroloana tsa amorphous calcium phosphate (ACP) tse tsoang likhetleng tsa mahe a likhoho, tse bohlokoa bakeng sa ho thehoa ha masapo a nang le mineralized - ke hore, a thata le a matla - 'me a ne a kile a sebelisoa e le sebaka sa lesapo. ka lebaka la likarolo tsa eona.

Lisebelisoa tse tala tse phethahetseng

Ka lehlakoreng la hae, mofuputsi ea ka sehloohong oa phuputso, Kinali Ma, moprofesa Lefapheng la Biomaterials Univesithing ea Oslo, o itse: "Likhetla tsa mahe ke thepa e tala e loketseng bakeng sa ho etsa thepa ea ho hlomathisetsa masapo hobane e na le likarolo tse ngata tsa calcium. le phosphorus. Likarolo tse ling tse amanang le ho tsosolosoa ha masapo, tse kang magnesium le strontium, le tsona li fumanoa likhaketleng tsa mahe.”

Bafuputsi ba kentse likaroloana tsa ACP ho XNUMXD spheroid ho sekaseka hantle tšebetso ea masapo a likaroloana ka tšebelisano lipakeng tsa lisele tsa masapo a amohelang le thepa ea ho hlomathisetsa. Ba fumane hore limolek'hule tsa ACP tse likhetla tsa mahe a vitro li hlile li sebelisana le lisele tse hahang lesapo, hammoho le melemo ea hore e ne e se chefo, e sa sebetsane le 'mele, ebile e sebetsa hantle ho khothalletsa ho tsosolosoa ha masapo.

Theknoloji e tšepisang

"Theknoloji ena e na le ts'episo ea ho fana ka phepelo e sa lekanyetsoang ea lisebelisoa tsa ho kopanya lesapo tse tsitsitseng ha li ntse li fokotsa tšilafalo ea tikoloho," ho boletse Harvard Justin Hauge, oa Univesithi ea Oslo, Norway le mofuputsi ea lumellanang le thuto.

Bafuputsi ba ts'epa hore liphetho tsa bona li tla khothaletsa lipatlisiso tse ling mabapi le ts'ebeliso ea litšila tse tloaelehileng tsa lijo joalo ka biomaterials.

Hoa hlokomeleha hore mokhoa o tloaelehileng oa ho hlomathiseletsoa ha masapo lefatšeng ka bophara ke ho tlatsa likheo kapa likheo masapong ka lisebelisoa tse tsoang mehloling e fapaneng, ho kenyeletsoa li-autografts tse tsoang masapong a motho a le mong ea ntseng a buuoa, kapa ho tloha. li-grafts tse tsoang masapong a bafani, a bokelloang nakong ea Opereishene e kang ho nkela sebaka sa noka e entsoeng sterilized bakeng sa ho sebelisoa ha ho kenngoa masapo a bakuli ba bang.

Li-grafts tsa masapo li boetse li fanoa ho tloha masapong a sa pheleng a liphoofolo tse kang likhomo kapa likolobe, tse bitsoang xenogeneic, tse sebetsoang ka mocheso o phahameng ho thibela 'mele oa motho,' me hangata li na le boleng bo tlaase ho feta li-autografts kapa bafani.

Likhakanyo tsa linaleli tsa Maguy Farah tsa selemo sa 2023