Iswekile ephezulu yegazi kunye ne-migraine

Iswekile ephezulu yegazi kunye ne-migraine

Kuyaziwa ngokubanzi ukuba i-migraine ihambelana neempawu ezinxulumene ne-glucose, ezifana ne-insulin yokuzila ukutya kunye nohlobo lwe-2 yeswekile, ezixhaphake izifo ze-comorbid.

Kodwa iqela leenzululwazi zeYunivesithi yaseQueensland e-Australia lifumene ikhonkco elibonakalayo lemfuzo elinokuthi livule intsimi entsha yonyango lwezi ngxaki ziphazamisayo, ngokutsho kweNew Atlas, ecaphula iphephancwadi Human Genetics.

Intloko kunye nemigraines

Kwiinkcukacha, abaphandi beYunivesithi yaseQueensland baveze ikhonkco lofuzo kwiijene ezibonakala kwiintlungu ezininzi ze-migraine kunye nentloko, ekwazi ukumelana neempawu zeswekile yegazi, ebangela umonakalo ophindwe kabini kule ngxaki yezempilo.

Kuqikelelwa ukuba i-migraine ichaphazela ngaphezu kwe-10% yabemi behlabathi, kwaye iphindwe kathathu phakathi kwabasetyhini.

"Ukususela kwi-1935, i-migraine ichazwe njengentloko ye-glycemic," kusho uDale Nyholt, uprofesa kwiYunivesithi yaseQueensland yeZiko leGenomics kunye neMpilo yoMntu, wongezelela ukuba "iimpawu ze-glycemic ezifana nokumelana ne-insulin, i-hyperinsulinemia kunye ne-hypoglycaemia egazini, uhlobo. I-2 yeswekile ihambelana nentloko kunye ne-migraines.

Iziphumo zafika emva kokuba abaphandi bahlalutye i-genomes yamawaka ezigulane ze-migraine ukubona ukuba kukho naziphi na izixhumanisi zofuzo ezinokuchongwa.

Baphinde benza uhlalutyo lweempawu ezinqamlezayo ukuchonga imimandla ye-genomic eqhelekileyo, i-loci, imfuza kunye neendlela, kwaye emva koko bavavanyelwa ubudlelwane obunqamlezayo.

Inqanaba le-insulin egazini

Emva koko, uNjingalwazi uRafiq Islam, umphandi kwiYunivesithi yaseQueensland, wathi, "Phakathi kweempawu ezisithoba zeswekile yegazi eziye zafundwa, kwafunyaniswa ukuba kukho unxulumano olubalulekileyo lwemfuza phakathi kwe-insulin yokuzila (inqanaba le-insulin egazini) kunye ne-glycated hemoglobin ene-migraine kunye nentloko ebuhlungu.

Kwakhona wongezelela ukuba imimandla equlethe izinto eziqhelekileyo zomngcipheko wemfuza yafunyanwa phakathi kwe-migraine, i-insulin yokuzila, i-glucose yokuzila, kunye ne-hemoglobin ye-glycated, naphakathi kweentloko kunye nemimandla eqhelekileyo kwi-glucose, i-insulin yokuzila, i-hemoglobin ye-glycated, kunye ne-proinsulin yokuzila.

Uye wachaza ukuba iproinsulin okanye ipro-insulin yipro-hormone eyandulela isigaba sokwenza i-insulin emzimbeni.

unyango olutsha

Ukuphazamiseka kwe-Genetic kuyinyathelo elibalulekileyo eliya phambili ekuqondeni indlela i-migraines kunye neempawu ezihambelana nazo ze-glycemic zivela, kwaye zivula iindlela ezintsha kunye nezinomdla zongenelelo lwezonyango.

U-Nyholt uphinde wabonisa ukuba "ngokuchonga imibutho yofuzo, i-loci kunye nofuzo olubandakanyekayo ekuhlalutyweni kophando, umbutho we-causal wachazwa, ngoko ke ukuqonda ngakumbi ubudlelwane phakathi kwe-migraine, intloko kunye neempawu ze-glycemic zaphunyezwa."

U-Islam wongezelela ukuba iziphumo zophando "zinokubonelela ngeendlela zokuphuhlisa iindlela ezintsha zonyango zokulawula iimpawu ze-glycemic ze-migraine kunye nezigulane zentloko, ngokukodwa ukunyusa izinga le-insulin yokuzila ukukhusela kwiintloko."

Uqikelelo lukaFrank Hogrepet lubetha kwakhona