Amazinyo aluncedo ekunyangeni ukudakumba!!

Amazinyo aluncedo ekunyangeni ukudakumba!!

Izazinzulu zeYunivesithi yaseJohns Hopkins eUnited States zenza uhlolisiso olutsha lokuvavanya intlaba yamazinyo akhutshiweyo, athatyathwe kumaziko onyango lwamazinyo, ukuhlola umlinganiselo anokusetyenziswa ngawo njengendlela yokunyanga udandatheko, ngokutsho kweBritani “ Daily Mail” yapapashwa.

Uvavanyo olutsha lusekwe kwi-hypothesis yokuba iiseli ze-stem master, ezinokukhula zibe ziintlobo ezahlukeneyo zeeseli ezikhethekileyo, kwipulp inokunceda ukuvuselela ukubunjwa kwee-neuron ezintsha engqondweni.

Ukwanda kwemveliso yee-neurons

Abaphandi beYunivesithi yaseJohns Hopkins bakholelwa ukuba xa kukho ii-neurons ezininzi, ngcono uxhulumaniso phakathi kwezi seli kunye nemimandla yobuchopho ejongene neemvakalelo. Iiseli zestem nazo zichasene nokudumba, kwaye kucingelwa ukuba ukudakumba kunokunxulunyaniswa nokudumba kwengqondo.

Uvavanyo luza njengokuqhubeka kokufunyanwa kwempumelelo, okwenziwe ngaphambili, ukuba ii-antidepressants zinokuvuselela iiseli zengqondo ukuba zenze ii-neuron ezininzi.

i-serotonin

Kukwakholelwa ukuba ukuphazamisa amanqanaba eekhemikhali zengqondo kwingqondo efana ne-serotonin ngandlela thile kukhokelela kuxinzelelo, ngakumbi kuba uninzi lwee-antidepressants zenzelwe ukunceda ukonyusa amanqanaba e-serotonin, kodwa kuhleli ukuba ithiyori yokungalingani kweekhemikhali kwingqondo ayiqinisekanga. eqinisekisiweyo, njengoko Kukho ezinye izinto ezininzi ezinokukhokelela ekudakaleni, kubandakanywa ukuchaphazeleka kofuzo kunye neengxaki zobomi ezixinzelelekileyo. Kodwa abaphandi ngoku bacebisa ukuba ukukhula kwe-neuronal, kunye nokunxibelelana phakathi kwe-neurons, kudlala indima ebalulekileyo.

ummandla wehippocampus

Izifundo zangaphambili zifumene ukuba i-hippocampus, ebandakanyeka kwimemori kunye neenkqubo zeemvakalelo ekuphenduleni iinkumbulo, incinci kwizigulane ezinoxinzelelo olungapheliyo.

Kwaye ezinye iingcali ziye zacebisa ukuba ihippocampus encinci inokuchaza ukuba kutheni kuthatha ixesha elide ukuba ii-antidepressants ziqale ukusebenza. Banyusa iikhemikhali zobuchopho njenge-serotonin kunye ne-dopamine, kodwa kunokuthatha iiveki ezimbalwa ngaphambi kokuba zisebenze, ngoko ke kunokwenzeka ukuba isimo sengqondo siphucule njengoko ii-neuron ezintsha zikhula kwaye zenze unxibelelwano olutsha, inkqubo ethatha iiveki.

Ukuvuselela ukukhula kweeseli ze-stem

Uphando oluqhubekayo kwiYunivesithi yaseJohns Hopkins lubonise ukuba ii-antidepressants ziyakwazi ukuvuselela ukukhula kweeseli zengqondo. Kulingo olutsha, abantu abangama-48 abanokudakumba baya kunikwa iiseli ezitsalwa kwipulp yamazinyo abanye abantu, ukongeza kwi-antidepressant fluoxetine.

Iiseli zicutshungulwa kwaye zicocwe ngaphambi kokuba zifakwe kwiingalo zezigulane kwiiseshoni ezine, iiveki ezimbini ezihlukeneyo, zikhumbula ukuba iqela lokuthelekisa lithatha kuphela i-fluoxetine yonke imihla.

Anti-inflammatories

Ethetha ngale ndlela, uCarmine Pariant, unjingalwazi we-Biological Psychiatry kwiKholeji yaseKing yaseLondon, uthi: “Ngexesha elifutshane, uxinzelelo lwandisa ukuveliswa kweekhemikhali emzimbeni ezinceda ekulweni okanye ekubalekeni. Ngokomzekelo, uxinezeleko lubangela ukudumba, nto leyo ekhusela [umntu] kusulelo. Noko ke, ukuxinezeleka ngokwasengqondweni nangokwentlalo okubangela ukudandatheka, njengokungaqeshwa, iingxaki zomtshato okanye ukufelwa, kudla ngokuba lixesha elide. Ekuhambeni kwexesha, ukwanda kokudumba kunciphisa ukuzalwa kweeseli ezintsha zobuchopho nonxibelelwano phakathi kweeseli zengqondo, nto leyo ekhokelela kudandatheko.”

Wongeza ukuba iiseli ze-stem zikwa "anti-ukudumba", ngoko ke ukongeza ekudaleni iiseli zobuchopho ezintsha, zinokunciphisa iziphumo zokudumba koxinzelelo kwingqondo. Iiseli ze-Stem zaziwa ngokufikelela kwiindawo apho kukho ukudumba, ngoko ke ziya kufumana indlela yazo ukusuka egazini ukuya kwingqondo.

Yintoni ukuthula okukohlwayayo, kwaye uhlangabezana njani nale meko?