I-Botox yonyango lweemeko zengqondo kunye nezengqondo

Uphononongo olutsha lufumanisa ukuba iinaliti zeBotox zinokunceda ukukhulula iimpawu zeemeko zempilo yengqondo ezifana nokudakumba kunye noxinzelelo. I-BTX ye-toxin ye-toxin ye-botulinum, ebizwa ngokuba yi-"Botox", isetyenziselwa ngokukodwa kwiinkqubo zokuthambisa, kuba ibangela ukuphumla kwemisipha, kwaye xa isetyenziswe kwiindawo ezithile zobuso, i-Botox inokunciphisa imigca kunye nemibimbi, ngokutsho kwe-EuroNews. uphononongo olupapashwe kwijenali yeeNgxelo zeNzululwazi.

"Imisipha yosizi"

Ukuphumla kwemisipha ebusweni kuye kwaba ngumxholo wezifundo ezininzi, njengoko izazinzulu zifuna ukubona ukuba zingasetyenziselwa ukukhulula iimpawu zeemeko zempilo yengqondo. Ngokukodwa, ingcamango kukuba unokujolisa kwi-biologist ye-evolution uCharles Darwin ebizwa ngokuthi "izihlunu ezibuhlungu."

"Yonke le nkalo yophando isebenzisa i-toxin ye-botulinum njengonyango lokuphazamiseka kwengqondo isekelwe kwi-hypothesis yempendulo yobuso," kusho uDkt Axel Wollmer, ingcali yengqondo kunye nomphandi kwiYunivesithi yaseSemmelweis eHamburg kunye nomnye wababhali abakhokelayo kwisifundo. .

Wongezelela ngelithi le ngcamango yaqala kuDarwin noWilliam James (owaziwa ngokuba “nguyise” wenzululwazi yengqondo yaseMerika) ngenkulungwane yeshumi elinesithoba, ebonisa ukuba ithi inkangeleko yobuso bomntu ayidluliseli nje kuphela imeko yakhe yeemvakalelo kwabanye, kodwa ikwayibonakalisa. kuye ngokwakhe.

Ingcamango yeyokuba ngoxa ezinye iinkangeleko zobuso ezinjengokufinga iintshiyi zibangelwa ziimvakalelo ezingakhiyo, inkangeleko yobuso ngokwayo iyaziqinisa ezo mvakalelo kumjikelo ombi.

“Omnye womeleza omnye kwaye unokunyukela kwinqanaba elibalulekileyo lokuvuselela iimvakalelo ezinokuba ngumcimbi kwiimeko zempilo yengqondo,” utshilo uWoolmer.

Ekunye nabaphandi baseHannover Medical School eJamani, uWollmer kunye neqela lakhe bazimisele ukwakha kuphando lwangaphambili lokutofa iBotox kwingingqi yeglabella, indawo yobuso ngaphezulu kwempumlo naphakathi kwamashiya, ahlala ebonisa uxinzelelo lomntu. xa ufumana iimvakalelo ezingalunganga.

Nje ukuba izihlunu zobuso zisebenze ukubonisa imvakalelo, umqondiso wokuvuselela umzimba uyaveliswa, obuya ebusweni ukuya kwingqondo yeemvakalelo kwaye yomeleze kwaye igcine le meko yeemvakalelo, utshilo uWoolmer. Kuphela kukukubonakaliswa kwezi mvakalelo athi ubani azive eneemvakalelo ezifudumeleyo nezipheleleyo, okanye emva kokuba le meko ithotyiwe, iimvakalelo ziyadamba yaye aziqondwa ngolo hlobo.”

ukuphazamiseka kobuntu bomda

Ngokuphumza imisipha yentlungu, abaphandi bafuna ukubamba okwenzekayo kwingqondo xa i-loop yempendulo echanekileyo iphukile, ngoko bavavanya izigulane ze-45 ezine-borderline personality disorder (BPD), enye yezona zinto zixhaphakileyo zobuntu.

Iqela labaphandi lachaza ukuba izigulane ezine-BPD zihlupheka ngenxa "yeemvakalelo ezimbi kakhulu", kuquka umsindo kunye noloyiko. Wollmer uthe izigulana ze-BPD "ngandlel 'ithile, ngumzekelo wokuxakwa ngokuphindaphindiweyo neqela leemvakalelo ezingalunganga abangenako ukuzilawula ngokwenene." Emva koko abanye abathathi-nxaxheba bophononongo bafumana iinaliti zeBotox, ngelixa iqela lolawulo lafumana i-acupuncture.

Umfanekiso wemagnetic resonance yengqondo

Ngaphambi kokuba unyango kunye neeveki ezine emva koko, abathathi-nxaxheba banikwa into ebizwa ngokuba yi-emotional "go / no-go" umsebenzi, apho kwakufuneka balawule ukusabela kwabo kwiimpawu ezithile ngelixa bebona imifanekiso yobuso ngeendlela ezahlukeneyo zokubonakaliswa kweemvakalelo, ngelixa abaphandi. baphonononge iingqondo zabo besebenzisa umfanekiso osebenzayo wemagnethi. Ulingo luvelise iziphumo ezixubeneyo, kunye nezigulane zeBotox kunye ne-acupuncture ezibonisa ukuphuculwa okufanayo emva kwonyango, kodwa iqela labaphandi lakhuthazwa zezinye iziphumo ezimbini.

Ngee-MRI scans, kwafunyaniswa okokuqala ukuba iinaliti zeBotox ziyiguqula njani imiba ye-neurobiological ye-BPD.

"Sifumene umphumo wokuzola kwi-amygdala, ebandakanyeka kakhulu ekuqhubeni iimvakalelo ezingathandekiyo kwaye ixhaphake kakhulu kwizigulane ze-BDD," watsho u-Wollmer, wongezelela ukuba umphumo ofanayo awubonwanga kwiqela lolawulo eliphathwa nge-acupuncture.

Abaphandi baye baqaphela ukuba iinaliti ze-Botox zanciphisa ukuziphatha okungxamisekileyo kwezigulane ngexesha "lokuhamba / lokungahambi" umsebenzi, kwaye yayanyaniswa nokusebenza kwemimandla ye-lobe yangaphambili yengqondo ebandakanyeka kulawulo lokuthintela.

Unyango lweBotox yokudakumba

Uphando lwangaphambili luye lwajonga indlela ii-injection zeBotox ezinokuthi ziphule i-loops yempendulo kwezinye iindawo zobuso kunye nomzimba.

Uhlalutyo lwe-meta lwango-2021 oluvavanya idatha evela kwizigulane ezingama-40 ezifakwe kwi-Botox kwi-database ye-US Food and Drug Administration yafumanisa ukuba ukuphazamiseka kwexhala kwakukho i-22 ukuya kwi-72 yepesenti engaphantsi kunezigulane ezifumene ezinye unyango kwiimeko ezifanayo. Uphando olufanayo lwenziwa ngo-2020 kwiziphumo zoxinzelelo lwenaliti yeBotox, ebonise ukuba ingasetyenziselwa ukunyanga uxinzelelo kunye nokuluthintela.

Wollmer uthe unyango olusekwe kakuhle olufana nonyango lwengqondo okanye i-antidepressants alusebenzi ngokwaneleyo malunga nesinye kwisithathu sezigulana ezinoxinzelelo, "ngoko ke, kukho imfuneko yokuphuhlisa iindlela zonyango olutsha, kwaye apha iinaliti zeBotox zinokuba nendima," echaza. ithemba lakhe kunye neqela lakhe lophando ukubona iziphumo., ephandwe ngakumbi kwiSigaba sesi-XNUMX solingo lwezonyango, apho abaphandi baya kubona ukuba nayiphi na enye imeko yempilo yengqondo inokunyangwa ngendlela yokutofa kweBotox.