Ukuvezwa ngokuqhubekayo kwimiphumo ye-stimulants kuchaphazela ukukhulelwa !!

Ukuvezwa ngokuqhubekayo kwimiphumo ye-stimulants kuchaphazela ukukhulelwa !!

Uphononongo olutsha lunxibelelene nokuvezwa kwi-phthalates, iqela lemichiza, phambi kokukhulelwa kwimpilo yabasetyhini yokuzala. Iziphumo zophononongo zongeza kubungqina obukhulayo malunga neziphumo ezibi zezi khemikhali ngokuchonga indlela i-phthalates enciphisa ngayo amathuba okukhulelwa, isiphithiphithi kunye neehomoni ezibalulekileyo zokuzala, ngaphezu kwezizathu ezifunyenwe ngaphambili zokudumba kunye noxinzelelo lwe-oxidative, ngokutsho kwapapashiweyo. yiwebhusayithi yeAtlas eNtsha, icaphula iiNdlela zeMpilo yokuSingqongileyo.

Isepha kunye nokuhlamba umzimba

I-Phthalates liqela leekhemikhali ezenziwe ngumntu ezidla ngokusetyenziswa njengezinyibilikisi, iiplastiki, kunye nezizinzisi kwiimveliso zokhathalelo lomntu ezifana nesepha, ukuhlamba umzimba, iziqholo, ipolishi yeenzipho, ishampu, ijeli yeenwele, kunye ne-hairspray. Iiphthalates zikwafumaneka kwezinye iimveliso ezifumaneka kufutshane nekhaya, ezinje ngomgangatho wevinyl, ukupakishwa kweplastiki, imibhobho yegadi, kunye nezinto zokudlala.

Yitya, usele kwaye uphefumle

Ngokutsho kwamaZiko e-US oLawulo lweSifo kunye noThintelo (CDC), abantu bavezwa kwi-phthalates ngokutya nokusela ukutya okuye kwadibana neekhemikhali, kunye nokuvezwa okuthile okwenzeka ngokuphefumla amasuntswana asemoyeni. Uphononongo lubonise ukuba ukuvezwa kwezinye iindidi ze-phthalates kuphazamisa inkqubo ye-endocrine kwaye kwandisa ukuvuvukala kunye noxinzelelo lwe-oxidative.

Uphononongo olutsha, olwenziwa zizazinzulu kwiYunivesithi yaseMassachusetts, luvavanye ubudlelwane phakathi kokuvezwa kwangaphambi kokukhulelwa kwi-phthalates kunye namathuba omfazi okukhulelwa nokugcina ukukhulelwa, kunye nefuthe labo ekudumbeni kunye noxinzelelo lwe-oxidative.

I-Endocrinology kunye nohlalutyo lomchamo

"I-phthalates ye-Ubiquitous evezwa yonke imihla ikhokelela ekuphazamisekeni kwe-endocrine," watsho uCarrie Nobles, umphandi okhokelayo wophando.
Abaphandi bahlalutya idatha efunyenwe njengenxalenye yophando malunga nemiphumo ye-aspirin ekukhulelweni nasekuzaleni, eyalandela abafazi be-1288 ngexesha lemijikelezo emithandathu yokuya esikhathini ngelixa bezama ukukhulelwa kwaye balandela abafazi abakhulelweyo ngexesha lokukhulelwa. Umndilili weminyaka yabathathi-nxaxheba yayingama-28 eminyaka. Idatha yalungiselelwa ubudala, isalathisi sobunzima bomzimba, uhlanga / ubuhlanga, ukutshaya icuba, ukulingana, okanye inani lamaxesha owasetyhini abelethe umntwana ongekazalwa oneminyaka engama-24 ubudala okanye ngaphezulu.

iihomoni zokuzala

“Sikwazile ukujonga ezinye zezinto ezivezwa yimekobume ezifana ne-phthalates kunye nendlela ehambelana ngayo nokuba kuthatha ixesha elingakanani ukukhulelwa,” utshilo uNobles. Xa umzimba uqhekeza i-phthalates, i-metabolites ikhutshwe kumchamo. Abaphandi bahlalutya i-20 phthalate metabolites kunye neehomoni zokuzala kwiisampulu zomchamo zabathathi-nxaxheba kunye namanqanaba e-serum e-C-reactive protein, i-biomarker yokudumba.

Iimetabolites ze-phthalate

Ngokuqhelekileyo, ukugxilwa komchamo kwangaphambi kokukhulelwa kweemetabolites ezininzi ze-phthalate zaye zadibaniswa nokunciphisa amathuba okukhulelwa ngaphakathi komjikelezo omnye wokuya esikhathini (amandla okuchuma), kuquka i-2-diethylhexyl-XNUMX, i-di-N-butyl, kunye ne-benzyl-butyl metabolites. Kodwa kwakungekho budlelwane obucacileyo phakathi kwe-phthalate metabolites kunye nomngcipheko wokulahleka kokukhulelwa.

Kuyavela, ngokukaNobles, ukuba kukho iikhompawundi ezintathu zantlandlolo zephthalate “ezibonakala zinxulunyaniswa ngamandla nokuthatha ixesha elide ukukhulelwa: i-DEHP, efumaneka kwiimveliso zeplastiki ze-polyvinyl chloride ezifana nezinto zokudlala, izixhobo zevinyl, iikhethini zeshawa, izinto zokuncamathelisa. , kunye nokupakishwa kokutya, ukongeza kwi-pesticides kunye nezithambiso. I-DBP ikwafumaneka kwi-hairspray, i-nail polish, kunye nezinye iziqholo, phakathi kwezinye izinto zendlu. I-BzBP ifumaneka kwezinye iibhegi, amabhanti kunye nezihlangu, kwaye kancinci kwezinye iimveliso zokhathalelo lomntu.

I-estradiol ephantsi

Amanqanaba aphezulu e-phthalate metabolites adityaniswa nokuncipha kwe-estradiol, ihomoni ye-steroid elawula umjikelezo wokuya exesheni, ngexesha lokuya exesheni kwaye idityaniswe ngokuqhubekayo namanqanaba aphezulu e-FSH kunye ne-luteinizing hormone, esebenza ngokuhambelanayo ukulawula i-ovulation, yonke into. ezidlala indima ebalulekileyo ekukhuleni kwangoko.

UNobles wathi ezi zalathi “zibonakala ngokwenene kumabhinqa anengxaki yokungasebenzi kakuhle kwesiyilelo-maqanda, okunokwenzeka ngenxa yobudala nangenxa yezinye izinto.”

Ukuvuvukala kunye noxinzelelo lwe-oxidative

Abaphandi baye bafumanisa ukuba abafazi abanamazinga aphezulu okuvezwa kwi-phthalates nabo banamazinga aphezulu okudumba kunye noxinzelelo lwe-oxidative, enokonakalisa iiseli kunye ne-DNA kwaye ikhokelele kwizifo. Abaphandi bathi indalo ekhoyo yonke indawo ye-phthalates yenza kube nzima kubasetyhini ukulawula ukubonakaliswa kwabo kubo nangona bethatha amanyathelo okhuseleko ayimfuneko, njengokujonga iilebhile zemveliso yabathengi kunye nokukhetha iinketho ezingenazo i-phthalate, kuba bavezwa kubo ngeendlela ezininzi, kubandakanya uthuli oluvela. Imigangatho kunye nezinye izinto, ukusuka kwizinto zasekhaya, ukufunxa ulusu lweemveliso zokhathalelo lomntu kunye nepolisi yeenzipho kunye neziqholo, ukubonakaliswa kwesondlo ngenxa yokupakishwa kokutya, ukongeza ekutyeni imithombo yokutya engcolileyo kunye namanzi okusela.

I-Capricorn ithanda i-horoscope yonyaka ka-2024