Uphando olutsha noluthembisayo lonyango lwezigulane zentliziyo

Uphando olutsha noluthembisayo lonyango lwezigulane zentliziyo

Abaphandi base-Australia baye bafezekisa iinjongo ezimbini zokuqala eziza kunceda umzamo wehlabathi jikelele wokulwa nesifo senhliziyo: oko kukuthi, ukwenza intliziyo encinci ibetha kunye ne-vascular system yayo, kwaye okwesibini ukufumanisa indlela inkqubo ye-vascular echaphazela ngayo umonakalo wentliziyo obangelwa ukuvuvukala.

Izigidi zokufa ngonyaka

Ngokutsho kwewebhusayithi ye-“New Atlas”, icaphula ijenali “yeeNgxelo zeSeli”, izifo zentliziyo ziphakathi kwezona zizathu ziphambili zokufa kwihlabathi liphela.” Ngokutsho kweWorld Health Organisation “WHO”, izifo zentliziyo zibanga ubomi obuqikelelwa kwi-17.9 yezigidi. ukusuka kwizifo zentliziyo kulindeleke ukuba kunyuke, xa kujongwe ukwaluphala kwabantu kunye nefuthe lemingcipheko yokuphila.

Isifo senhliziyo

Isifo se-Cardiovascular disease sibandakanya nayiphi na imeko echaphazela intliziyo okanye ukujikeleza kwegazi, njengokuhlaselwa kwentliziyo, isifo se-coronary artery, uxinzelelo lwegazi oluphezulu, i-stroke, kunye ne-vascular dementia.Ngenxa yokuxhaphaka kwe-CVD, kubalulekile ukuba uphando luqhubeke lutyhila iindlela ezintsha zokuthintela kunye xilonga eli qela lezifo kwaye ulinyange.

Izakhiwo ezincinci ezilinganisa intliziyo

Abaphandi base-Australia baye bakhawuleza uphando kwinkalo yesifo senhliziyo ngokwenza i-organelles, izakhiwo ezincinci ezilinganisa amalungu omntu, ezikhule kwibhubhoratri esebenzisa iiseli ze-pluripotent zabantu, ezinokudalwa ngokusebenzisa "i-reprogrammed" yesikhumba okanye iiseli zegazi.

UJames Hudson, omnye wabaphandi kolu hlolisiso, wathi: ‘Ilungu ngalinye lentliziyo lilingana nembewu ye<em>chia, lizimilimitha ezisisi-1.5 kuphela ububanzi, kodwa ngaphakathi kukho iiseli ezingama-50000 XNUMX ezimela iindidi ngeendidi zeeseli ezenza intliziyo. .

Ukusuka kwiqela le-organelles encinci, abaphandi benza intliziyo ebethayo.Inyathelo ngokwalo alikho elitsha, kodwa liyisihlandlo sokuqala ukuba iiseli ze-vascular, iiseli ezihambelana nemithambo yegazi, zinokudibaniswa ngempumelelo, zisondeza intliziyo yomzekelo. intliziyo yomntu yokwenyani.

U-Hudson uthe: "Ukufakwa kweeseli ze-vascular okokuqala kwimisipha yentliziyo encinci kubaluleke kakhulu kuba zifunyenwe zidlala indima ephambili kwi-biology ye-tissue, njengoko iiseli ze-vascular zenza i-organelles isebenze kakuhle kwaye ibethe ngamandla, kwinto entsha. okokuqala oko kuya kunceda ukuyiqonda ngakumbi intliziyo.” ukwenza umzekelo ngokuchanileyo kwesi sifo.

Ukufumanisa okongeziweyo

Ibhonasi eyongeziweyo yeeseli ze-vascular ithetha ukuba abaphandi banokuphanda indlela abachaphazela ngayo ukuvuvukala, oku kunokubangela ukuba i-atherosclerosis kunye nokuvuvukala kwemisipha yenhliziyo.Kwesinye isifundo, abaphandi babonise indima ephambili yenkqubo ye-vascular edlala kwi-inflammation-induced heart muscle injury.

Indima enkulu kwiiseli ze-vascular

U-Hudson uthe, "Xa ukuvutha kuvuselelwe kwimisipha encinci yentliziyo, kwafunyaniswa ukuba iiseli ze-vascular zidlala indima enkulu," njengoko kubonakala ukuqina kwezicubu, eziqulethe iiseli ze-vascular kuphela, oku kuthetha ukuba iiseli zaziva oko kwenzekayo. yaza yatshintsha indlela eziziphatha ngayo, yaye ngaloo ndlela kwafunyaniswa ukuba iiseli zikhupha into ebizwa ngokuba yiendothelin elamla isifo sokuqaqamba kwamalungu omzimba.”

Abaphandi bathi ukufunyanwa okuqhubekayo, kudibaniswa nokusetyenziswa kwe-organoids entsha yentliziyo, kunokukhokelela kunyango olutsha lwesifo senhliziyo ngokukhawuleza.

Izintso kunye nezifo zengqondo

Ukupapasha uphononongo, abaphandi bathi, kuya kunceda abaphandi kwihlabathi liphela ukuba benze ezabo ii-organoids zemithambo yegazi, ukonyusa iinzame zehlabathi zokulwa nesifo sentliziyo. .

Uqikelelo lukaMaguy Farah lwehoroscope yonyaka ka-2023