Unyango lomhlaza wePancreatic ngenxa yecorona

Unyango lomhlaza wePancreatic ngenxa yecorona

Izazinzulu zenze impumelelo ekuphuhliseni isitofu sokugonya umhlaza emva kokuba besebenzise ubuchwepheshe obufanayo obusetyenziswa kuphuhliso lwesitofu sokugonya intsholongwane kaCorona, elenziwe yiNkampani yePiontech-Pfizer. amajoni omzimba ukuhlasela iiseli zomhlaza.

Iingcali ezisemva kophuhliso lwe-vaccine ye-Pfizer ziye zasebenzisana noogqirha kwisiXeko saseNew York ukuphuhlisa isitofu sokugonya kwizigulane zomhlaza we-pancreatic, ngokutsho kwephephandaba laseBrithani, "I-Telegraph".

Iziphumo zolingo lwezonyango lwesigaba I, esokuqala kolo hlobo, zabhengezwa kule mpelaveki kwinkomfa yonyaka yeAmerican Society of Clinical Oncology (ASCO) eChicago.

Izazinzulu zinethemba lokuba iziphumo zivakalisa ixesha elitsha lonyango lwezinye izifo zomhlaza ekunzima ukuzinyanga, njengoko umhlaza we-pancreatic udla ngokubizwa ngokuba "ngumntwana wepowusta" wezo zidumbu ezibulalayo.

Indlela yokusebenza yesitofu sokugonya

Kwaye malunga neenkcukacha zovavanyo, zafumana izigulane ezingamashumi amabini kunye ne-pancreatic adenocarcinoma (PDAC), emele malunga ne-90% yazo zonke iimeko zomhlaza we-pancreatic, kuvavanyo.

Ezi zigulana zenziwa utyando ukususa umhlaza, kwaye emva kweeyure ezingama-72 iisampulu zabo zethumba zathunyelwa kwi-BioNTech eJamani kunyango kunye nesitofu sokugonya umntu ngamnye, esilawulwa ngemithambo kwisigulane.

Izigulana zikwafumene unyango lwe-immunotherapy ukunceda ukukhulisa impendulo yabo.

Emandleni ogonyo lweCorona

Ugonyo olutsha lusebenzisa i-mRNA, ikhowudi yemfuza evela kwithumba, ukufundisa iiseli zomzimba ukwenza iprotein evuselela impendulo yomzimba, itekhnoloji efanayo esetyenziswa kugonyo lweCorona oluveliswe yinkampani iPfizer-BioNTech.

Umzimba ke ufunda ukuba iiseli zomhlaza ngenene zingaphandle kwaye zithumela iiseli ze-T ukuba zizikhangele kwaye zizibulale ukuba zibuyile.

iziphumo ezithembisayo

Izigulana ezilishumi elinesithandathu zafumana idosi yokuqala kwezilithoba zesitofu sokugonya kwiiveki ezisithoba emva kotyando, kwaye isiqingatha sazo savelisa impendulo ebalulekileyo yamajoni omzimba.

Kananjalo, zonke izigulana ezisibhozo zazingenawo umhlaza kwiinyanga ezili-18, zicebisa ukuba iiseli ze-T zisebenze sisitofu sokugonya ukuphinda umhlaza.

Nangona kunjalo, izigulane ezisibhozo azizange ziphendule kwisitofu sokugonya, ngelixa abathandathu babona umhlaza wabo uvela emva nje konyaka, kwaye abaphandi basaphanda ukuba kutheni isiqingatha seqela singaphendulanga.

UNjingalwazi u-Ozlem Turise, umseki kunye nomlawuli wezonyango we-BioNTech, uthe zipesenti ezintlanu kuphela zabaguli abanomhlaza wepancreatic abaphendule kunyango.

“Sizibophelele ekuhlangabezaneni nalo mceli mngeni ngokwakha kuphando lwethu ekudala silufumana kwizitofu zokugonya umhlaza kunye nokuzama ukwaphula umhlaba omtsha wokunyanga amathumba anzima ukunyanga,” wongeze watsho.