Indlela yokubuyisela amandla emisipha echaphazelekayo yi-atrophy?

Indlela yokubuyisela amandla emisipha echaphazelekayo yi-atrophy?

I-muscular dystrophy ichaphazela ukuya kuthi ga kwi-16% yabantu abadala behlabathi kwaye yenye yezona zinto ziphambili ekuphulukaneni nokuzimela kunye nokuxhomekeka kuncedo lwabanye okanye ukusetyenziswa kweendlela zonyango kunye nezixhobo. Idibaniswa nokulahlekelwa kwemisipha, umsebenzi okanye amandla, kwaye yimbangela enkulu yokuwa okuninzi, ukukhubazeka kokuhamba, kunye nokwehla kokusebenza kwabantu abadala. Kwakhona, akukabikho "unyango" okanye unyango lokumisa ukuphuhliswa kwayo, makungabikho ukubuyisela umva, kwaye ukungenelela okuninzi kuxhomekeke ekunciphiseni ukulahleka kwemisipha ngokuguqula indlela yokuphila kunye nokutya, ngokutsho kwapapashwa yi-New Atlas website, echaza. Iinkqubo zeNational Academy of Sciences (PNAS).

Ukubuyiselwa kweeseli ze-atrophic muscle

Yintoni entsha kukuba izazinzulu kwiDaegu Gyeongbuk Institute of Science and Technology (DGIST) eMzantsi Korea ziye zaphumelela ekuphuhliseni unyango olutsha lwe-bioelectrical olubuyisela iiseli ze-muscle kwiigundane ezikhulileyo, kwaye bavakalisa ukuzithemba ukuba kuya kuba nefuthe elifanayo ebantwini. iimodeli.

"Inani lezigulana ezine-muscular dystrophy linyukile kutsha nje ngenxa yezithintelo kwimisebenzi yentlalo ngenxa yobhubhani we-Covid-19 kunye nokwaluphala kwabantu behlabathi," utshilo umphandi okhokelayo uMinsok Kim, unjingalwazi kwiSebe leBiology eNtsha eDaegu Gyeongbuk. Institute, egxininisa ukuba, okwesihlandlo sokuqala, kukho ithuba lokusebenzisa iyeza le-bioelectrical ukunyanga i-muscular dystrophy, isifo esinganyangekiyo okwangoku.

Ukuvuselela kombane

UKim wongeze ukuba yena kunye neqela lakhe lophando bakwazile ukuchonga iimeko ezifanelekileyo zokuvuselela umbane zokuvuselela izihlunu njengomsebenzi weminyaka yobudala, nto leyo enokukhokelela ekutshintsheni kweparadigm kuphuhliso lonyango lonyango lomntu.

Inqanaba elifanelekileyo lobunzima bemisipha

Iqela liphuhlise i-biochip-based based screening screening platform ye-biochip yokuguga kweeseli zomzimba womntu. Ukusebenzisa oku, baye bakwazi ukuchonga iimeko ezifanelekileyo zokuvuselela umbane, okunceda ukuhlaziya iiseli ze-muscle eziguga. Nangona ukuvuselela umbane kungonakalisa izihlunu, abaphandi baye bafumanisa inqanaba elifanelekileyo elinokunceda ukucela impendulo echanekileyo kwi-calcium signaling, ukuguga, kunye ne-metabolism, ngakumbi ekubeni ukubuyisela ukubonakaliswa kwe-calcium ekugugeni kwe-skeletal muscle kunokukhokelela kwi-hypertrophy, okanye Ukunyuka kwe-muscle mass.

Ukuphucula ukusebenza kwezihlunu

Uvavanyo lubonise ukunyuka okuncinci kwamandla okunciphisa imisipha kunye nokwakheka kwezicubu, ebonisa ukuba unyango aluzange lwakhiwe kuphela ubunzima, kodwa luphuculwe umsebenzi. Nangona i-preliminary, iqela labaphandi likholelwa ukuba lingatshintsha indlela yokuvuselela umbane ngoku.

Itekhnoloji ye-Electrosilver

Iqela labaphandi kuphononongo liqaphele ukuba "okwangoku, izixhobo ezininzi zokuvuselela imisipha yombane zisetyenzisiwe kwizibhedlele kunye namakhaya ngaphandle kokuqwalasela iimeko ezifanelekileyo zokuvuselela," kwaye ucebise ukuba "kufuneka kubekho isicelo sokuvuselela umbane ngokukodwa kunyango lwe-atrophy ye-muscle. ngenxa yokuguga ukuphumeza ubuninzi "Ukusebenza ngakumbi kunye neziphumo ebezingalindelekanga ezincinci."

Abaphandi bavakalise umnqweno wabo wokuba obu bugcisa bubizwe ngokuba “yitekhnoloji ye-electro-silver,” besithi “iziphumo zolu phando [olutsha] mhlawumbi ziya kuba sisiseko sophuhliso lweyeza le-bioelectrical elinikezelwe kwi-muscular dystrophy.”

Uqikelelo lukaMaguy Farah lwehoroscope yonyaka ka-2023