Ngaba izitofu zokugonya zibonelela ngokhuseleko iminyaka emininzi?

Ngaba izitofu zokugonya zibonelela ngokhuseleko iminyaka emininzi?

Ngokubhekiselele kumaza otshintsho lwe-corona kwihlabathi liphela kunye nokwanda kwenani losulelo, uphononongo lwakutsha nje luveze ukuba izitofu ezimbini ze-Pfizer kunye neqabane layo elithi "Bionic", ukongeza kwiModerna, zinokubonelela ngokhuseleko kwintsholongwane yeCorona iminyaka. okanye ubomi.

Uphononongo lwase-US lufumanise ukuba uninzi lwabantu abagonywe ngogonyo lwe-mRNA banokungadingi iidosi ezongezelelweyo ze-booster, okoko nje intsholongwane kunye neentlobo zayo ezintsha zingaguquki kakhulu.

"Luphawu oluhle lokuzinza kokugonyeka kwethu kusetyenziswa esi sitofu," utshilo u-Ali Al-Yaidi, umphathi wophononongo kunye noprofesa oncedisayo kwiYunivesithi yaseWashington eSt.

Iiseli zamajoni omzimba ziyimfihlelo

Ugqirha kunye noogxa bakhe kuphononongo bafumanise ukuba iiseli zokhuselo lomzimba eziyibonayo le ntsholongwane zihlala emizimbeni yabantu abaye baphola kwi-corona kangangeenyanga ezisibhozo emva kokosuleleka.

Kwakhona, uphando oluqhutywe lelinye iqela lubonise ukuba iiseli ezibizwa ngokuba yi "memory B" ziyaqhubeka zikhula kwaye zomelela ubuncinane unyaka emva kosulelo.

Kuphononongo olutsha, izazinzulu zacebisa ukuba ugonyo luya kuhlala iminyaka, kwaye mhlawumbi ubomi, kubantu abosulelwe yintsholongwane kwaye bagonywe kamva, kodwa akuzange kucace kubo ukuba ugonyo lulodwa lunokuba nefuthe lexesha elide. ziyafana nabo babenesi sifo ngaphambili.

Ke, iqela lijonge kumthombo weeseli zememori, i-lymph nodes, apho ezi seli zokhuselo lomzimba ziqeqeshelwa ukuqaphela kunye nokulwa intsholongwane.

Baye bafumanisa ukuba emva kosulelo okanye ugonyo, isakhiwo esibizwa ngokuba liziko lentsholongwane lenza kwii-lymph nodes. Kukwesi sakhiwo apho iiseli ziqeqeshelwa ngamandla ukulwa le ntsholongwane.

Okukhona ezi seli ziziqeqesha ixesha elide, kokukhona zikwazi ukunqanda iintlobo zentsholongwane ezinokuthi zivele.

Uphuhliso lwe-B-cell lukhusela kwintsholongwane

Ngokunxuseneyo, uMarion Pepper, ugqirha wamajoni omzimba kwiYunivesithi yaseWashington eSeattle, wachaza ukuba wonke umntu uhlala egxile ekuveleni kwentsholongwane, ephawula ukuba olu phononongo lubonisa ukuba "iiseli ze-immune B nazo ziyavela, okuthetha ukuba olu phuhliso luqhubekayo zikhusele kwintsholongwane.”

Ngethuba lophononongo, iqela lifunde idatha yabantu abangama-41, kubandakanywa abasibhozo abanembali yosulelo lwentsholongwane, kwaye bonke bagonywa ngeedosi ezimbini zesitofu sokugonya "i-Pfizer", kwaye iqela lathatha iisampulu kwii-lymph nodes. Abantu abali-14 emva kweeveki ezintathu, ezine, ezintlanu, ezisixhenxe kunye ne-15 emva kwedosi yokuqala.

Abaphandi bafumanise ukuba iiveki ezili-15 emva kwedosi yokuqala yesitofu sokugonya, iziko lentsholongwane lisasebenza kakhulu kubo bonke abathathi-nxaxheba abali-14, kwaye inani leeseli zememori "B" eziye zaqaphela intsholongwane azizange zehle.

Ukongeza, u-Al Yabidi wachaza ukuba "ukuqhubeka kwempendulo malunga neenyanga ezine emva kokugonywa luphawu oluhle kakhulu," njengoko amaziko e-microbial ahlala efikelela incopho yawo kwiiveki ezimbini emva kokugonywa aze aphele.

Abantu abadala kunye nabakhubazekileyo badinga i-boosters

Kwelakhe icala, uDipta Bhattacharya, ugqirha wamajoni omzimba kwiDyunivesithi yaseArizona, wathi amaziko entsholongwane avuselelwe zizitofu zokugonya "mRNA" aqhubekile nokusebenza kwiinyanga emva kokuba yenzekile.

Ugxininise ukuba ukubaluleka kophononongo kuxhomekeke kwinto yokuba uninzi lwezinto ezaziwa zizazinzulu malunga nokuqhubeka kobukho bamaziko eentsholongwane zisekwe kuphando lwezilwanyana, kwaye olu phononongo lolokuqala ebantwini.

Iziphumo zibonisa ukuba uninzi lwabantu abagonyiweyo luya kuba nokugonyeka kwexesha elide kwiintlobo zangoku ze-coronavirus.

Kodwa abantu abadala, abantu abanamajoni omzimba abuthathaka, kunye nabo bathatha amayeza acinezela amajoni omzimba banokufuna i-boosters.

Ngokuphathelele abantu abachachayo kwintsholongwane kwaye bagonyiwe, banokungawadingi kwaphela, njengoko amanqanaba e-antibody enyuka ngenxa yokuba iiseli zememori “B” zazikhula phambi kogonyo.

Uphononongo lubonise ukuba kunzima ukuqikelela ubude bexesha lokugonyeka kusetyenziswa amayeza okugonya i-mRNA, kodwa xa kungabikho bunzima obunokuthi bubaleke ukhuselo lomzimba, kuba ngokwethiyori kunokwenzeka ukuqhubeka ubomi.

Eminye imixholo: 

Ujongana njani nesithandwa sakho emva kokubuya ekwahlukaneni?

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