Le yindlela okwenzeka ngayo ukufa ngentsholongwane yeCorona

Intsholongwane ye-corona ekhulayo ayihlaseli ngokuthe ngqo inkqubo yokuphefumla, kodwa ihlasela iiseli ezibomvu zegazi. ” Esi sisiphumo sephepha lophando elipapashwe yiwebhusayithi yeChemRxiv, eqhutywa yi-American Chemical Society, iRoyal Society of Chemistry eBritane kunye neGerman Chemical Society, kwiinyanga emva kokusasazeka kobhubhane lwehlabathi, okushiya ngaphezulu kwe-100 yamaxhoba. .

Kwaye indawo yasasaza uphononongo lokuba indlela ubhubhane wehlabathi ohlasela ngayo umzimba yahluke ngokupheleleyo kwinto exhaphakileyo okanye eqondwayo ukuza kuthi ga namhlanje, iphawula ukuba oku kungaqondani kusemva kokunyuka kokusweleka kwabantu kwihlabathi liphela.

Kwiinkcukacha, uphononongo lubonise ukuba i-corona ayichaphazeli ngokuthe ngqo inkqubo yokuphefumla, kodwa endaweni yoko ihlasela iiseli ezibomvu zegazi, ngakumbi ikhonkco le-beta 1.

Kuyaziwa ukuba iiseli ezibomvu zegazi ziiseli ezithwala ioksijini kwaye ziyithuthele kwezinye iiseli zomzimba wonke.

Iiseli ezibomvu zegazi zineproteni i<em>hemoglobin, ethi yona iqulethe i<em>iron.

IHemoglobin ithwala ioksijini ngokuyibophelela, ukutsala ikharbon diokside emzimbeni ize iyise emiphungeni ukuze ikhutshwe.

Into eyenziwa yintsholongwane kaCorona kukuhlasela ikhonkco le-beta 1, ukurhoxisa ngokukodwa iprotheni ye-hemoglobin, ngaloo ndlela yehlisa imetabolism ye-iron (Heme Metabolism) kwiiseli, ibangela ukunqongophala kweoksijini kwiseli ngokwayo.

Ngapha koko, ukungabikho kweoksijini kwiiseli kubangela ityhefu yeeseli zemiphunga, okukhokelela kusulelo ngenxa yokungakwazi ukutshintshiselana ngecarbon dioxide eyingozi kunye neoksijini enenzuzo rhoqo, etshabalalisa iiseli kwaye yenzeke. Ukufa.

Ngokophononongo, i-chloroquine inokuthintela intsholongwane ekuhlaseleni iprotein ye-hemoglobin ukuya kuthi ga kwinqanaba elithile, kwaye ithobe ngokufanelekileyo iimpawu zokuphefumla.

Ukufa kuthwaxa uDonald Trump nomhlobo wakhe owazalelwa eSyria ngenxa yeCorona

I-Chloroquine ibisetyenziswa kakhulu kwisithuba esingaphezu kwesiqingatha senkulungwane ehlabathini, ukunyanga isifo seengcongconi kunye nezinye izifo ezosulelayo, njengoko kwakuthenjelwe kuyo ngowe-1949 njengechiza elomeleza amajoni omzimba ukuze akwazi ukujongana nezifo nobhubhane kunye nobhubhane. ukumelana neentlungu, umkhuhlane kunye nosulelo, kunye nemiphumo yayo kwizigulane ziyaziwa ngooGqirha, njengoko i-World Health Organization kunye nezinye ii-NGOs zonyango, ezifana nooGqirha Ngaphandle kwemida, baye babhenela ekusebenziseni ukunyanga izigulane ze-malaria kwimimandla emininzi yehlabathi.

I-China iphakathi kwamazwe okuqala ukuvavanya i-chloroquine ukunyanga abantu abosulelwe yintsholongwane yeCorona ekuqaleni kukaFebruwari.

Nangona kunjalo, zonke ezi ngasentla ziingxoxo nje ezingakhange zingqinwe ziyinyani. Ngokwesayithi, olu phononongo liphepha lengxoxo yezifundo kuphela, kwaye ukuqinisekiswa kwalo kufuneka kuqinisekiswe ngokuqhuba iimvavanyo ezininzi kwiindawo ezingaphezu kwenye.