Alzheimer's prevention twenty years ago!!

Alzheimer's prevention twenty years ago!!

A new study in mice has found that exposing the brain to electrical currents can prevent symptoms of dementia for up to 20 years before they appear.

According to what was published by the British newspaper “Daily Mail”, citing the journal Nature Communications, the study discovered that it is possible to stop the deterioration of brain cells and prevent memory loss and cognitive decline by targeting the areas of rodent brains that are damaged during Alzheimer’s disease.

20 years before diagnosis

The researchers attached low-level wavelength electrodes, which were surgically attached to the brains of laboratory mice, to prevent harmful proteins from forming in the brain and the brain's memory center from shrinking once a month.

The results of the study revealed that electrical currents prevent deterioration that can be a sign of Alzheimer's disease, which can be present as early as 10 to 20 years before the disease is diagnosed in humans.

Sleep state

“This indicates the possibility of predicting the disease in a state of remission, before the onset of cognitive decline,” said study co-researcher Dr. Ina Slutsky.

The study monitored changes in the brain that occur during sleep, which are believed to often occur when early signs of the condition appear, specifically in the hippocampus, which is the memory center in the brain.

Mechanisms that delay symptoms

The researcher pointed out that “there are mechanisms that compensate for the same disease while awake, thus prolonging the period before symptoms of the disease appear,” as laboratory mice experienced “silent seizures” in the hippocampus during sleep, which look like seizures when examining the brain but do not cause any external symptoms. But the healthy mice had decreased activity, meaning the silent seizures could be signs of brain deterioration.

Deep brain stimulation

To prevent this overactivity, the researchers used deep brain stimulation (DBS), a surgical procedure in which electrodes are placed in specific areas of the brain. These electrodes are connected by wires to a device placed under the skin near the chest.

The device sends electrical impulses any time the brain produces abnormal signals, such as those that lead to memory and balance problems and speech difficulties. DBS is also used in the United States to treat neurological disorders such as Parkinson's disease, epilepsy, dystonia, and obsessive-compulsive disorder.

Common symptoms

Alzheimer's disease is the most common form of dementia, and is an umbrella term used to describe a group of progressive neurological disorders (those affecting the brain), which affect memory, thinking and behaviour.

Common symptoms include memory loss, poor judgment, confusion, repeated questions, difficulty communicating, taking longer to complete normal daily tasks, acting reckless, and problems with movement.

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