Alƙawarin maganin kwayoyin halitta don dawo da ji ga yara kurame

Alƙawarin maganin kwayoyin halitta don dawo da ji ga yara kurame

Wani ci gaba na gwaji na asibiti ta hanyar amfani da maganin kwayoyin halitta ya maido da ji ga yara biyar da aka haifa kurame. Bayan watanni shida, yaran sun sami damar fahimtar magana da kuma gudanar da tattaunawa, wanda hakan ya sanya fatan yin amfani da shi sosai nan gaba kadan, bisa ga abin da shafin yanar gizon New Atlas ya buga, ya ambato mujallar Science Advances.

Halin gado

Majinyatan da ke cikin gwajin sun yi fama da wani yanayi na kwayoyin halitta mai suna autosomal recessive deafness 9 (DFNB9), wanda ya haifar da maye gurbi a cikin wata kwayar halitta mai suna OTOF, wanda ke samar da furotin otoferlin, wanda ke taimakawa wajen watsa wutar lantarki daga cochlea zuwa kwakwalwa, inda zai iya. a fassara su azaman sauti - amma ba tare da shi ba, waɗannan sigina ba za su taɓa zuwa ba. Saboda maye gurbi guda ɗaya ne ke haifar da shi kuma baya haɗa da wani lahani na jiki ga sel, ƙungiyar ta ce DFNB9 shine ɗan takara da ya dace don irin wannan nau'in jiyya.

A cikin binciken da masu bincike daga Harvard Medical School, Massachusetts Eye and Ear, da Fudan a kasar Sin suka gudanar, maganin kwayoyin halitta ya hada da tattara kwayoyin halittar OTOF a cikin masu dauke da kwayar cutar kwayar cutar da kuma allurar a cikin ruwan kunnen ciki. Daga nan sai kwayoyin cutar suka binciko kwayoyin halitta a cikin cochlea kuma suka sanya kwayar halittar a cikin su, wanda ya ba su damar fara samar da furotin autoferlin da ya ɓace kuma ya dawo da ji.

Cochlear implant

Yara shida, masu shekaru tsakanin shekara ɗaya zuwa bakwai, waɗanda DFNB9 ta bar su gaba ɗaya kurma su ma sun shiga cikin binciken. An saka majiyyata hudu tare da ƙwanƙwasawa, wanda ya ketare matsalar kuma zai iya ba su damar koyon fahimtar magana da sauran sautuna. A wannan yanayin, an dakatar da dashen.

gagarumin cigaba

Bayan maganin kwayoyin halitta, an bi yaran har tsawon makonni 26. A wancan lokacin, biyar cikin shida sun nuna ci gaba sosai, inda manyan yara uku suka iya fahimta da amsa magana, yayin da biyu suka iya ɗauka a cikin ɗaki mai hayaniya suna ci gaba da tattaunawa ta wayar tarho. Wasu daga cikin yaran sun yi ƙanƙanta da ba za su iya yin gwajin da aka saba yi ba, amma an same su suna amsa sauti, har ma sun fara faɗin kalmomi masu sauƙi kamar “mama.” An yi gyare-gyare a hankali a hankali, amma ƙungiyar ta ba da rahoton cewa yaran sun fara nuna sakamako kafin gwajin farko makonni huɗu bayan haka.

Sanadin kwayoyin halitta da tsufa

Jagoran binciken Yilai Xu, ya bayyana cewa, za a ci gaba da sanya ido kan wadanda suka halarci wannan gwaji, yayin da za a gudanar da bincike kan sauran mutane. Tawagar ta ce amincewa da maganin a Amurka na iya ɗaukar tsakanin shekaru uku zuwa biyar. An gwada irin waɗannan hanyoyin maganin ƙwayoyin cuta don asarar ji mai alaƙa da kwayoyin halitta ko shekaru.

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