Anan ne mafita don tsaftace arteries ba tare da magani ba

Anan ne mafita don tsaftace arteries ba tare da magani ba

Masu bincike daga Jami'ar Kasa ta Singapore sun gano yadda kwayoyin halittar jinin jini ke mu'amala da fararen kwayoyin halittar jini da ake kira macrophages don rage kumburi da samuwar kitse a bangon jijiyoyin jini.

Sun ce binciken nasu ya ba da damar yin maganin wannan cuta ta gama gari, wanda zai iya haifar da bugun zuciya da bugun jini.

Kwayoyin jinin jini

Babban hanyar isar da iskar oxygen daga huhu zuwa kyallen jikin jiki shine kwayoyin jajayen jini.

Kwayoyin jajayen jini a zahiri suna samar da kwayoyin da ake kira RBCEV vesicles extracellular a lokacin tsufan tantanin halitta, jihohin cuta, da kuma martani ga matsalolin muhalli.

RBCEV vesicles suna kare RBCs ta hanyar cire ƙwayoyin cuta masu haɗari, suna shafar ƙwayoyin rigakafi, da shiga cikin tsarin kumburi.

Arteriosclerosis

Atherosclerosis, tarin kitse, cholesterol da sauran abubuwa a cikin bangon arteries, yanayi ne na yau da kullun wanda zai iya haifar da bugun zuciya, bugun jini, aneurysm ko gudan jini.

Macrophages, fararen jinin jini wadanda sune "masu amsawa na farko" na tsarin rigakafi, suna taka muhimmiyar rawa a cikin atherosclerosis ta hanyar cin abinci, tarawa da kuma canza lipids zuwa ƙwayoyin kumfa wanda ke taimakawa da kuma kula da ci gaban atherosclerotic plaques.

Ciwon macrophages masu mutuwa

Sabon binciken ya yi nazari kan hulɗar tsakanin vesicles na RBCEV da fararen jini a cikin bege na gano hanyar da za a dakatar da atherosclerosis. PS ya nuna, akan membranes cell.

Saboda vesicles na RBCEV suna da yawan PS akan jikinsu, masu binciken sun toshe masu karɓar PS akan macrophages, wanda ya rage yawan karɓa.

Kare kwayoyin halitta daga oxidation

Bayan daukar nauyin RBCEV vesicles, macrophages sun rage matakan pro-inflammatory sunadaran kuma sun samar da matakan da suka fi girma na wani enzyme wanda ke kare kwayoyin halitta daga lalacewar oxidative sau da yawa ana gani a cikin cututtuka na zuciya da jijiyoyin jini. Har ma mafi mahimmanci, RBCEVs sun sanya macrophages juriya don zama ƙwayoyin kumfa.

A cewar mujallar Extracellular Vesicles, masu binciken sun jaddada cewa ci gaba da yin nazari kan illolin RBCEV vesicles ta yin amfani da nau'ikan dabbobi na atherosclerosis na iya haifar da ci gaban wannan dandamali na warkewa.

Hasashen horoscope na Maguy Farah na shekarar 2023