Yaushe ne cututtukan arthritis ke ƙarewa a cikin inna, kuma zai iya haifar da mutuwa?

Rheumatoid amosanin gabbai wani kumburi ne na yau da kullun wanda yawanci yana shafar haɗin gwiwar hannu, ƙafafu, gwiwoyi, hips da kafadu.

Idan wannan yanayin ya ci gaba na tsawon lokaci, zai iya haifar da lalacewa na dindindin ga tendons, ligaments da guringuntsi, da nakasar ƙasusuwa da haɗin gwiwa.

Ba a san musabbabin cutar ba, amma tana iya zama kwayoyin halitta, kuma tana iya shafar yadda tsarin garkuwar jiki ke aiki. Misali, mutanen da ke dauke da kwayar halittar HLA-DR sun fi kamuwa da cutar fiye da sauran mutane.

Alamomin cutar

Rheumatoid amosanin gabbai wani ci gaba ne, yanayin bayyanar cututtuka wanda ke haifar da lalacewar haɗin gwiwa na dindindin wanda ke daɗaɗawa akan lokaci, kuma yana haifar da raguwar zamantakewa da aiki. Daga cikin alamomin asibiti na rheumatoid amosanin gabbai akwai; Ƙunƙarar haɗin gwiwa, yawanci a cikin sa'o'i na safe, kumburin haɗin gwiwa wanda zai iya shafar kowane haɗin gwiwa, amma yawanci ƙananan haɗin gwiwa na hannaye da ƙafafu daidai, gajiya, zazzabi, asarar nauyi da damuwa. Rheumatoid amosanin gabbai kuma yana da alaƙa da wasu munanan yanayi, kamar lalacewar haɗin gwiwa na dindindin wanda zai iya haifar da rashin iya aiki, da ƙarin haɗarin cututtukan jijiyoyin jini da kamuwa da cuta. Yaduwar cutar Rheumatoid amosanin gabbai yana shafar kusan kashi 1% na manya a duniya.

Adadin matan da ke fama da cutar ya ninka adadin maza. Wannan cuta na iya faruwa a kowane shekaru, amma galibi tana faruwa tsakanin shekaru arba'in zuwa saba'in.

Don gano cutar, dole ne a yi gwaje-gwaje da yawa, saboda yana da wuya a gano shi daidai, kuma alamunta suna bayyana ne kawai tare da wucewar lokaci. Ana gano cutar sau da yawa akan alamomi da yawa, ciki har da nau'in cututtukan haɗin gwiwa da aka shafa da sakamakon haskoki na X-ray da gwaje-gwajen hoto, waɗanda ke nuna lalacewar haɗin gwiwa da babban matakin "maganin rigakafi da ake kira rheumatoid factor a cikin jini" da kuma rigakafin. Babban darajar CCP. Tasirin tattalin arziki na RA yana da tasirin tattalin arziki a kan majinyata, saboda yawan kuɗin da ake kashewa a kaikaice ya sa su kasa aiwatar da ayyukansu na yau da kullun. Nazarin da aka yi a Turai ya nuna cewa tsakanin kashi 20 zuwa 30 cikin 66 na marasa lafiya na rheumatoid arthritis sun kasa yin aiki a cikin shekaru uku na farko na kamuwa da cuta. Bincike ya kuma nuna cewa kashi 39 cikin 21 na marasa lafiya na rheumatoid amosanin gabbai sun rasa matsakaicin kwanakin aiki 70 a kowace shekara. A Turai, an kiyasta kashe kuɗin kai tsaye na 'rashin iya aiki' da kuma kai tsaye 'kuɗin kula da lafiya' ga al'umma ya kai dala XNUMX ga kowane majiyyaci a kowace shekara. Tasirin gazawar mutum wajen yin aiki da mu'amala da jama'a na iya kara hadarin damuwa da damuwa. Jiyya na farko Lalacewar haɗin gwiwa na iya faruwa da sauri a farkon matakai na rheumatoid amosanin gabbai, kuma lalacewar haɗin gwiwa ya bayyana a cikin XNUMX% na gwajin X-ray akan marasa lafiya a cikin shekaru na farko da na biyu na kamuwa da cuta. MRI kuma yana nuna canje-canje a cikin tsarin haɗin gwiwa idan aka kwatanta da abin da suka kasance watanni biyu bayan bayyanar cutar. Saboda lalacewar haɗin gwiwa na iya faruwa da sauri a farkon cutar, za a iya buƙatar gaggawa don fara magani mai mahimmanci bayan an gano shi, da kuma kafin mummunan lalacewar haɗin gwiwa ya faru, wanda zai haifar da rashin dawowa daga komawa zuwa ga kafin. jihar rauni. Maganin cututtukan cututtuka na rheumatoid ya sami babban canji a cikin shekaru goma da suka gabata, yayin da magani ya tashi daga hanyar ra'ayin mazan jiya da nufin sarrafa alamun asibiti zuwa hanyar da ta fi dacewa da aka tsara don rage lalacewar haɗin gwiwa da nakasa.

Manufar farko na maganin cututtukan cututtuka na rheumatoid shine don hana ci gaban cutar, ko abin da aka sani a wani yanayi kamar rage cutar. A tarihi, an yi maganin rheumatoid amosanin gabbai tare da magungunan da ba na steroidal anti-inflammatory irin su ibuprofen ko ƙananan analgesics wanda ke kawar da ciwo da bayyanar cututtuka. Duk da haka, waɗannan magungunan a halin yanzu ana maye gurbinsu da waɗanda aka gyara magungunan anti-rheumatoid waɗanda ke da tasiri mai tasiri akan jiki da kuma hana lalacewa na dogon lokaci ga tsarin haɗin gwiwa. Ilimin Halittu Wani sabon nau'in jiyya da ake kira biologics don maganin ƙwanƙwasa amosanin gabbai an ƙirƙira kwanan nan, wanda aka kera daga sunadaran mutane da dabbobi masu rai. Yayin da wasu magungunan ke da tasiri mai mahimmanci akan tsarin rigakafi, an tsara ilimin halittu musamman don ƙaddamar da tsaka-tsakin da aka yi imanin suna da hannu a cikin tsarin kumburi. Kuma wasu abubuwan halitta suna toshe ayyukan sunadaran halitta a cikin jiki. Binciken da aka yi ya nuna cewa magungunan ƙwayoyin cuta suna iyakance haɓakar lalacewar haɗin gwiwa, suna hana cutar daga lalacewa, kuma suna ba da damar marasa lafiya su rage girman cutar, bisa ga sakamakon X-ray, wanda aka kimanta ta hanyar rediyo da gwaje-gwaje na maganadisu. Ingantaccen magani da wuri ba wai kawai yana rage cutar ba ko ma yana dakatar da ci gaban kamuwa da cuta, amma yana inganta yanayin rayuwa, kuma yana rage tsadar rayuwa.