Ib tug neeg raug tus kab mob COVID-19 li cas?

Ib tug neeg raug tus kab mob COVID-19 li cas?

Raws li kev tshawb fawb txuas ntxiv nthuav qhia tus cwj pwm ntawm tus kab mob Corona, uas tau ua rau lub ntiaj teb ua rau muaj ze li ob xyoos, cov kws tshawb fawb ntawm University of Glasgow Center rau Kev Tshawb Fawb Kab Mob hauv Scotland tau txheeb xyuas cov noob uas cuam tshuam rau tus neeg mob hnyav npaum li cas rau Covid-19. .

Tib lub sijhawm, cov kws tshawb fawb uas nws txoj kev tshawb fawb tau luam tawm hauv phau ntawv xov xwm "Science" ceeb toom txog kev pheej hmoo ntawm kev tshwm sim ntawm tus kab mob Corona tshiab, tsis quav ntsej txog kev tiv thaiv ntuj uas cov noob no muab rau qee tus neeg.

Txoj kev tshawb no kuj tau taw qhia tias ib yam ntawm cov proteins uas tsim tawm hauv lub cev siv cov noob "OAS1" tuaj yeem txheeb xyuas tus kab mob "SARS Cove 2" tau zoo, thiab tiv thaiv tus kab mob hnyav.

rhuav tshem cov kab mob

OAS1 noob, paub txog kev tshawb fawb, pib lub voj voog ntawm cov txheej txheem uas ua rau ribonuclease L, ib qho enzyme uas rhuav tshem cov kab mob uas nkag mus rau hauv lub cell thiab txhawb lub cev tiv thaiv kab mob los tua kab mob.

Txawm li cas los xij, cov kws tshawb fawb tau taw qhia tias raws li "cov lus qhia" muaj nyob rau hauv "OAS1", ib qho ntawm ob hom sib npaug ntawm cov protein uas paub txog cov kab mob thiab ua rau lub cev tiv thaiv kab mob tuaj yeem tsim tau, luv "p42" lossis ntev "p46", Thiab tsuas yog tom kawg yog siv tau los tiv thaiv tus kabmob coronavirus, uas ua rau muaj kev sib kis, uas muaj ib pab pawg tshwj xeeb ntawm cov molecules txuas nrog rau nws, uas pab txhawb kev sib cuam tshuam ntawm cov protein nrog cell membranes (cov no hu ua prenylated proteins).

Tsis tas li, txoj kev tshawb fawb tau qhia txog qhov tseem ceeb ntawm kev ceeb toom tias qhov kev qhia ua ntej ntawm "OAS1" cuam tshuam nrog kev tiv thaiv cov ntaub ntawv hnyav ntawm "Covid 19", thiab qhov no qhia tau tias lub cev tiv thaiv kab mob no yog ib qho tseem ceeb ntawm cov tshuaj tiv thaiv kab mob.

Hauv teb chaws Africa thiab Europe

Cov txiaj ntsig no tau txais los ntawm kev tshawb fawb ntawm genomes ntawm 499 tus neeg uas tau mus pw hauv tsev kho mob nrog tus kab mob Corona, hauv 212 ntawm lawv, lub cev tsis tsim "p46", thiab ntawm cov pab pawg no, kev pheej hmoo ntawm kev tuag thiab kev nkag mus rau kev saib xyuas hnyav. yog ib thiab ib nrab npaug siab dua lwm pab pawg.

Lawv kuj tau qhia tias tsis yog txhua tus muaj cov noob caj noob ces ua lub luag haujlwm tsim "p46" isoform, uas paub zoo txog cov qauv ntawm tus kabmob Corona, raws li cov kws tshawb fawb qhia tias nws muaj ntau dua ntawm cov neeg African thiab cov neeg tsiv teb tsaws chaw los ntawm qhov no. Tebchaws Europe ntau dua li lwm qhov, thiab lawv tau hais tias Tsawg dua ntawm cov neeg nyob hauv lub nroog ntawm Peru, Lima (11% ntawm cov neeg mob), thiab ntau dua ntawm cov neeg sawv cev ntawm Ishan cov neeg hauv Nigeria (70% ntawm cov neeg mob). Thaum cov neeg European nyob hauv qhov chaw thib ob.

Cov kws tshawb fawb tau pom tias qhov kev pheej hmoo ntawm ntau tus neeg rau Covid-1 tuaj yeem nyob ntawm qhov tseeb ntawm qhov "tsim nyog" sib txawv ntawm OASXNUMX hauv cov pejxeem.

gimmick thiab nrawm nrawm

Raws li xibfwb Sam Wilson, tus thawj coj ntawm Glasgow Virus Research Center, hais tias, nws muaj peev xwm hais tias tus kab mob Covid-19 yuav kawm dhau sijhawm los hla txoj kev tiv thaiv no, uas nws tsis tau ntsib dua ua ntej. OAS1 noob tsis muaj nyob hauv cov neeg nqa khoom tseem ceeb ntawm "SARS-Cove-2", horseshoe bats.

Thiab British TV channel "ITV" tau hais tawm Wilson hais tias qhov kev tshawb fawb "qhia tau tias tus kabmob coronavirus uas ua rau tus kabmob SARS tshwm sim xyoo 2003 tau kawm nyob deb ntawm OAS1, sau tseg tias kev hloov pauv tshiab los ntawm "SARS-Cove-2" yog tias koj tswj tau. los ua tus tswv Txoj haujlwm no yuav dhau los muaj peev xwm kis tau tus kab mob ntau dua thiab yuav kis tau yooj yim dua ntawm cov neeg tsis tau txhaj tshuaj, uas pom tias yuav tsum tau saib xyuas tas li ntawm qhov kev hloov pauv tshiab "SARS-Cove-2" tshwm sim.

Koj ua li cas nrog ib tug neeg uas ntse tsis quav ntsej koj?

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