Kodi nyamakazi imatha liti kufa ziwalo, ndipo kodi ingayambitse imfa?

Rheumatoid nyamakazi ndi kutupa kosalekeza komwe nthawi zambiri kumakhudza ziwalo za manja, mapazi, mawondo, chiuno ndi mapewa.

Ngati vutoli likupitirirabe kwa nthawi yaitali, likhoza kuwononga kosatha kwa tendons, ligaments ndi cartilage, ndi kuwonongeka kwa mafupa ndi mafupa.

Palibe chomwe chimadziwika kuti chimayambitsa matendawa, koma akhoza kukhala obadwa nawo, ndipo angakhudze momwe chitetezo cha mthupi chimagwirira ntchito. Mwachitsanzo, anthu omwe ali ndi jini ya HLA-DR amatha kudwala matendawa kuposa anthu ena.

Zizindikiro za matenda

Rheumatoid nyamakazi ndi njira yopita patsogolo, yodziwika bwino yomwe imayambitsa kuwonongeka kwamagulu komwe kumawonjezereka pakapita nthawi, motero kumabweretsa kuchepa kwa chikhalidwe ndi magwiridwe antchito. Zina mwa zizindikiro za matenda a nyamakazi ndi; Kulimba kwapakati, nthawi zambiri m'maola a m'mawa, kutupa kwamagulu komwe kungakhudze mgwirizano uliwonse, koma makamaka timagulu tating'ono ta manja ndi mapazi symmetrically, kutopa, kutentha thupi, kuwonda ndi kuvutika maganizo. Rheumatoid nyamakazi imagwirizanitsidwanso ndi zovuta zina, monga kuwonongeka kwa mgwirizano kwamuyaya komwe kungayambitse kulephera kugwira ntchito, komanso chiopsezo chowonjezeka cha matenda a mitsempha ndi matenda. Kuchuluka kwa matendawa Matenda a nyamakazi amakhudza pafupifupi 1% ya akuluakulu padziko lonse lapansi.

Chiwerengero cha amayi omwe akudwala matendawa ndi kuwirikiza kawiri chiwerengero cha amuna. Matendawa akhoza kuchitika pa msinkhu uliwonse, koma nthawi zambiri amapezeka pakati pa makumi anayi ndi makumi asanu ndi awiri.

Kuti adziwe matendawa, mayesero angapo ayenera kuchitidwa, chifukwa n'zovuta kuti adziwe molondola, ndipo zizindikiro zake zimangowoneka pakapita nthawi. Matendawa nthawi zambiri amachokera ku zizindikiro zingapo, kuphatikizapo mtundu wa matenda a mafupa omwe akhudzidwa ndi zotsatira za mayeso a X-ray ndi kujambula zithunzi, zomwe zimasonyeza kuwonongeka kwa mafupa ndi kuchuluka kwa "antibody yotchedwa rheumatoid factor in the blood" ndi anti- Mtengo wa CCP. Mphamvu yachuma ya nyamakazi ya nyamakazi imakhala ndi zotsatira zachuma kwa odwala ake, chifukwa kuchuluka kwa ndalama zosalunjika kumapangitsa kuti asamagwire ntchito zawo za tsiku ndi tsiku. Kafukufuku ku Ulaya akusonyeza kuti pakati pa 20 mpaka 30 peresenti ya odwala nyamakazi amalephera kugwira ntchito m’zaka zitatu zoyambirira za matenda. Kafukufuku wasonyezanso kuti 66 peresenti ya odwala matenda a nyamakazi amataya pafupifupi masiku 39 ogwira ntchito chaka chilichonse. Ku Ulaya, ndalama zachindunji za 'kulephera kugwira ntchito' ndi ndalama zosalunjika za 'zachipatala' kwa anthu ammudzi zayerekezedwa kukhala $21 pa wodwala pachaka. Zotsatira za kulephera kwa munthu kugwira ntchito ndi kuyanjana ndi anthu kungapangitse chiopsezo cha kuvutika maganizo ndi nkhawa. Kumayambiriro chithandizo olowa kuwonongeka akhoza kuchitika mwamsanga mu magawo oyambirira a nyamakazi nyamakazi, ndi olowa kuwonongeka limapezeka 70% ya X-ray mayeso odwala woyamba ndi wachiwiri zaka matenda. MRI imasonyezanso kusintha kwa mapangidwe a ziwalozo poyerekeza ndi zomwe zinali miyezi iwiri chiyambi cha matendawa. Chifukwa chakuti kuwonongeka kwa mgwirizano kumatha kuchitika mofulumira kumayambiriro kwa matendawa, pangafunike kufunikira mwamsanga kuti ayambe chithandizo chamankhwala atapezeka, ndipo chisanachitike kuwonongeka kwakukulu kwa mgwirizano, zomwe zimapangitsa kuti asathe kubwereranso ku pre- mkhalidwe wovulala. Chithandizo cha matenda a nyamakazi chasintha kwambiri m'zaka khumi zapitazi, popeza chithandizo chachokera ku njira yowonongeka yomwe cholinga chake ndi kuyang'anira zizindikiro zachipatala kupita ku njira yapamwamba kwambiri yochepetsera kuwonongeka kwa mgwirizano ndi kulemala.

Cholinga chachikulu cha chithandizo cha matenda a nyamakazi ndi kuteteza chitukuko cha matendawa, kapena zomwe zimadziwika m'nkhani ina monga kuchepetsa matendawa. M'mbiri, nyamakazi ya nyamakazi idachiritsidwa ndi mankhwala osagwiritsa ntchito steroidal anti-inflammatory monga ibuprofen kapena analgesics osavuta omwe amachepetsa ululu ndi zizindikiro. Komabe, mankhwalawa pakali pano akusinthidwa ndi mankhwala omwe amasinthidwa odana ndi nyamakazi omwe ali ndi mphamvu zoyendetsera thupi komanso amalepheretsa kuwonongeka kwa nthawi yaitali kwa olowa. Biologics Gulu latsopano lamankhwala lotchedwa biologics pochiza nyamakazi ya nyamakazi lapangidwa posachedwapa, lopangidwa kuchokera ku mapuloteni amoyo a anthu ndi nyama. Ngakhale kuti mankhwala ena amakhudza kwambiri chitetezo chamthupi, biologics amapangidwa makamaka kuti ayang'ane apakatikati omwe amakhulupirira kuti akugwira nawo ntchito yotupa. Ndipo zinthu zina zamoyo zimalepheretsa kugwira ntchito kwa mapuloteni achilengedwe m'thupi. Kufufuzaku kunasonyeza kuti mankhwala achilengedwe amachepetsa kukula kwa kuwonongeka kwa mafupa, amalepheretsa kuti matendawa asapitirire, ndipo amalola odwala kuchepetsa kuopsa kwa matendawa, malinga ndi zotsatira za X-ray, zomwe zinayesedwa ndi ma radiographs ndi maginito a resonance. Kuchiza kothandiza koyambirira sikungochepetsa matendawa kapena kuyimitsa kufalikira kwa matendawa, koma kumapangitsa kuti moyo ukhale wabwino, komanso kumachepetsa ndalama zomwe anthu amakumana nazo.