Kuwanikwa kune njodzi kunoshandura nzira yekurova kwemoyo

Kuwanikwa kune njodzi kunoshandura nzira yekurova kwemoyo

Kuzvimba kwakanyanya, kungave kutsvuka, kurwadziwa, kana maronda akatenderedza kukuvara, inzira yekuzivisa immune system kuti ikuvare inoda kupora.

Asi, kana mhinduro yezvirwere zvemuviri ikaramba iripo kwenguva yakareba, kuzvimba kusingaperi kunogona kutungamira kurwisa matishu ane hutano uye njodzi yekuva nechirwere chakakomba inowedzera.

Muchidzidzo chechangobva kuitika, boka revatsvakurudzi muAustralia rakawana zvinoshamisa, zvichiratidza kuti masero machena eropa anofamba sei kubva mutsinga dzeropa achienda kunzvimbo dzine utachiona, kuwanikwa kunovhura musuwo wekugadzira marapirwo anogona kumisa kana kuderedza kutapurirwa kweropa jena. masero mumakwara avo, nekudaro kuchengetedza Zvirinani mhedzisiro yezvirwere zvinokonzerwa nekuzvimba kusingaperi.

"breakaway" mechanism

Ongororo iyi, yakaitwa neCentenary Institute of Cancer Medicine uye Cell Biology muAustralia, yakaratidzawo nzira iyo neutrophils "inobvisa" kubva mutsinga dzeropa, ichivabvumira kufamba-famba nemuviri. Neutrophils rudzi rwemasero machena eropa izvo zvakakosha zvikamu zvekudzivirira muviri uye "yekutanga anopindura" kune kukuvara kana utachiona, asi zvakawanda zvechinhu chakanaka nekufamba kwenguva zvinogona kutungamirira kumamiriro ezvinhu asingagumi uye ane ngozi, maererano neNew Atlas.

PDI protein

Dr Joyce Chiu, anotungamira muongorori weongororo iyi kubva kuCentenary Research Center paUniversity yeSydney, vakati kuti vaende kunzvimbo ine utachiona, neutrophils dzinofanirwa kunamatira nekubvisa kubva kumadziro etsinga dzeropa, uye kuti kunyangwe zvichizivikanwa kuti sei. ma integrins anobatsira neutrophils kunamatirana, Asi hazvina kuzivikanwa kuti zvingaparadzana sei. "

Masayendisiti akaona puroteni yakavanzwa nemaneutrophils, protein disulfide isomerase PDI, inoita basa rakakosha mukugonesa maseru kuti aparadzane netsinga dzeropa, uye izvo Dr. Chiu vanotenda nekunangana neutrophil kuburitswa kunogona kuve kushoma.

Mishonga mitsva

Akawedzerawo kuti: "Mishonga mitsva inogona kugadzirwa kurambidza PDI, kudzivirira neutrophils kubva 'kusasunga' uye kutama kubva kumadziro etsinga. Kudzivirira neutrophils kubva kufamba-famba kunogona kubatsira kudzivirira kuzvimba kusingaperi nekudzikisira kugona kwavo kuungana panzvimbo dzekukuvara kana kutapukira. "

Kurova kwemoyo uye sitiroko

Nepo ma<em>neutrophils ari, ehe, akakosha kuti immune system iite kukuvara, kuderedza kugona kwavo kuunganidza nekukuvadza matishu ane hutano zvimwe zvine chekuita nezvirwere zvisingaperi zvine chekuita nekuzvimba senge heart attack uye sitiroko.

"Zvakawanikwa zvekutsvaga zvinogona kugadzira nzira yekurapa kutsva uye nzira dzekutungamira dzinokwanisa kuderedza kuwanda kwekuputika, uye zvinogona kuvandudza migumisiro kune vanhu vane chirwere chisingaperi chechirwere uye chirwere chemwoyo," akadaro Dr. Chiu.

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