Ho sibolloa hona ho thusa ho theola boima ba 'mele

Ho sibolloa hona ho thusa ho theola boima ba 'mele

Ho boloka boima ba 'mele ka nako e telele ke ntoa e holimo. 'Me lintlha tsa li-hormone, metabolism le methapo ea kutlo tse laolang boima ba' mele li bolela hore e ka ba taba ea baeloji ho feta matla feela.

E 'ngoe ea lintlha tse nyahamisang ka ho fetisisa ho ba bangata ke thibelo ea lik'halori, ka dieters e fumana halofo ea liponto tsohle tse lahlehileng nakong ea lilemo tse peli, le hoo e ka bang 80% ka mor'a lilemo tse hlano. Ba bang ba ka ’na ba ho nka e le ho hlōleha ha botho ’me ho ka ba le liphello tsa nako e telele ’meleng, maikutlong le kelellong, ho latela se hatisitsoeng ke New Atlas, ha se qotsa koranta ea Cell Metabolism.

ditaba tse molemo

Ntlheng ena, bafuputsi ba Max Planck Institute for Metabolic Research MPIMR le Harvard Medical School ba atlehile ho tseba phetoho ea bohlokoa litseleng tsa methapo bokong tse hlahang nakong ea ho ja, ka lipontšo tse matla haholo tse fetisetsoang methapong e le lipakeng tsa maikutlo a tlala. .

Bokhoni ba ho thibela matšoao ana bo ka thusa bo-ramahlale ho etsa liphekolo tse thusang batho ho boloka boima ba bona.

liphetoho bokong

Henning Fencelo, mofuputsi oa MPIMR ea neng a etelletse pele thuto eo, o re: “Lipatlisiso li shebana haholo le liphello tsa nako e khutšoanyane ka mor’a ho ja.” Empa seo phuputso ea morao-rao e neng e ikemiselitse ho tsepamisa maikutlo ho sona ke ho beha leihlo liphetoho bokong ka nako e telele.

Liphuputso tse fetileng li bontšitse kamoo li-neurone tse hlasimollang li lebisang keketsehong e matla ea tšebeliso ea lijo. Ba fumane hore litsela tsa neural tse lebisang ho AgRP neurons lia holisoa ha likhoto tsa lab li ne li le lijong 'me li lula li le maemong ao a matlafalitsoeng, ka lebaka la hore matšoao a tlala e feteletseng a bakile ho ja lijo tse ngata le boima ba 'mele kapele.

tlala ea methapo ea kutlo

"Mosebetsi ona o eketsa kutloisiso ea hore na methapo ea methapo e laola tlala," ho boletse sengoli-'moho Bradford Lowell oa Sekolo sa Bongaka sa Harvard.

"Pele re ile ra fumana sehlopha se seholo sa li-neurone tsa mantlha tse ikopantseng 'meleng le ho hlasimolla li-neurone tsa tlala tsa AgRP.

Thutong ea rona ea hajoale, re fumane hore khokahano ea "neurotransmitter" lipakeng tsa li-neurone tsena tse peli, ts'ebetsong e bitsoang synaptic plasticity, e eketseha haholo ka lijo le ho theola boima ba 'mele, e leng se bakang tlala e telele ea nako e telele.

Keketseho e fokolang ea boima ba 'mele

Ha bafuputsi ba thibela puisano lipakeng tsa li-neurone tseo, ts'ebetso ea AgRP e ile ea fokotseha mme karabelo ea likhoto tsa lab mabapi le ho ja lijo e ne e laoloa le ho feta. Ha ho makatse hore ebe sena se lebisa ho fokotseng boima ba 'mele.

Vincillo o ile a hlalosa hore liphello tsa thuto li fana ka tlhaloso le ho fana ka monyetla oa ho fokotsa phello ea phello ea oscillating ea thibelo ea caloric. Ka nako e telele, sepheo ke ho hlahisa mekhoa ea phekolo ho batho e ka thusang ho boloka boima ba 'mele ka mor'a ho ja lijo.

Likhakanyo tsa linaleli tsa Maguy Farah tsa selemo sa 2023