Ukunyanga usulelo oluqatha ngecorona ngo...?

Ulingo lwezonyango, iziphumo zalo ezipapashwe, ngoLwesithathu, kwijenali yezonyango ekhethekileyo, ibonise ukuba iyeza elithi "tofacitinib" kunyango lwe-arthritis libonise iziphumo ezithembisayo kunyango lwezigulana ezineempawu ezinzima ze-Covid-19 isifo.

Kwaye ulingo lwezonyango, iziphumo zalo zapapashwa "kwiNew England Journal of Medicine," lwenzeka kubantu abangama-289 ababenyangwa ezibhedlele kwiindawo ezili-15 ezahlukeneyo eBrazil ngenxa yeempawu ezinzima ze-Covid-19.

Isiqingatha sezi zigulane sanikwa i-tofacitinib (iipilisi ezimbini ze-10 mg yonke imihla) ngokudityaniswa nokhathalelo lwempilo oluqhelekileyo kwaye esinye isiqingatha sanikwa i-placebo enokhathalelo lwempilo olufanayo.

Emva kweentsuku ezingama-28, i-18% yeqela elifumene ichiza liye laphuhla ukusilela kokuphefumla (umzekelo, ifuna intubation okanye ukufikelela kwisixhobo sokuphefumla) okanye yasweleka, xa kuthelekiswa ne-29% yeqela le-placebo.

Kuzo zonke, i-5.5% yezigulane ze-placebo zafa, xa kuthelekiswa ne-2.8% kwiqela le-tofacitinib.

I-Tofacitinib ithengiswa phantsi kweemveliso ezahlukeneyo, kuquka i-Zeljans, ephethwe liqela laseMelika lamachiza Pfizer.

“Siyakhuthazeka ziziphumo zokuqala zovavanyo lwethu lwe-tofacitinib kwizigulana ezilaliswe esibhedlele ezinenyumoniya ebangelwa yi-Covid-19,” utshilo u-Otavio Berwanger, ugqirha kwisibhedlele sase-Albert Einstein kwa-Israyeli oqhube uvavanyo lweklinikhi ngokubambisana noPfizer.

I-Tofacitinib yamkelwe ukuba isetyenziswe e-United States ukunyanga isifo samathambo, isifo samathambo, kunye ne-ulcerative colitis.

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