Kutheni le nto iziphumo zecorona zihlala ixesha elide?

Kutheni le nto iziphumo zecorona zihlala ixesha elide?

Abaphandi kwiZiko leMax Planck leFiziksi kunye neNyango e-Erlangen, eJamani, bakwazile ukubonisa ukuba “i-Covid-19” ibutshintsha kakhulu ubungakanani kunye nokuqina kweeseli ezibomvu nezimhlophe zegazi, ngamanye amaxesha kangangeenyanga, besebenzisa indlela entsha ebizwa ngokuba yi-Covid-XNUMX. “i-real-time deformation cytometry.” Eyona, okanye i-RT-DC ngokufutshane.

Ubungqina obutsha buveze ukuba ushicilelo olusisigxina lwe "Covid-19" lunokuba ngenxa yefuthe lentsholongwane egazini labantu, nto leyo ekhokelela kutshintsho olusisigxina kwiiseli zegazi ezisabonakala kwiinyanga ezininzi emva kokufunyanwa kosulelo.

"Siye sakwazi ukubona utshintsho olucacileyo kunye nexesha elide kwiiseli - ngexesha losulelo olunzima kwaye nasemva koko," kuchaza i-biophysicist uJochen Guck, ovela kwi-Max Planck Institute yeSayensi yokuKhanya eJamani.

Kuphononongo olutsha, uGuk kunye noogxa bakhe abaphandi bahlalutya igazi lezigulane besebenzisa inkqubo ephuhlisiwe yangaphakathi ebizwa ngokuba yi-real-time distortion measurement (RT-DC), ekwaziyo ukuhlalutya ngokukhawuleza amakhulu eeseli zegazi ngomzuzwana kwaye babone ukuba babonisa. utshintsho olungaqhelekanga kumthamo wabo kunye nokwakheka kwawo.

Ezi ziphumo zinceda ukucacisa ukuba kutheni abanye abantu abosulelekileyo beqhubeka nokukhalaza ngeempawu ixesha elide emva kokuba bosulelwe yi-COVID-19. Abanye abaguli bakhathazwa ziziphumo zexesha elide zosulelo oluqatha lwentsholongwane, njengoko emva kweenyanga ezi-6 okanye ngaphezulu zokuchacha, baqhubeka nokuziva uphefumla omfutshane, ukudinwa kunye nentloko ebuhlungu, kwaye le meko, ebizwa ngokuba "yi-post-Covid-19 syndrome" , ayikaqondwa ngokupheleleyo.

Yintoni ecacileyo kukuba ngexesha lesi sifo, ukujikeleza kwegazi kudla ngokuphazamiseka, ukuvalelwa okuyingozi kunokwenzeka kwimizila yegazi kwaye apho ukuthuthwa kwe-oksijini kunqunyelwe, kwaye ezi zizinto zonke apho iiseli zegazi kunye neempawu zabo zomzimba zidlala indima enkulu. indima.

Iqela lezazinzulu lilinganisa imeko yomatshini yeeseli zegazi ezibomvu nezimhlophe ukuphanda lo mba, kwaye baye bakwazi ukubona utshintsho olucacileyo kunye nexesha elide kwiiseli, zombini ngexesha losulelo olubukhali okanye nasemva koko, kwaye bapapasha iziphumo zophando lwabo. i "Biophysical Journal".

Basebenzisa indlela yokuziphuhlisa ebizwa ngokuba yi "real-time deformation cytometry", esandul' ukuqatshelwa ngembasa edumileyo "Medical Valley", ukuhlalutya iiseli zegazi. Ngemakroskopu.Inkqubo yesiko lenkqubo ichonga iindidi zeeseli ezikhoyo, ukuba zinkulu kwaye zigqwetheke kangakanani, kwaye zinokuhlalutya ukuya kutsho kwi-1000 leeseli zegazi ngomzuzwana.

Le teknoloji isentsha, kodwa inokuhamba umgama omde ekuphononongeni into engekaziwa kwisayensi ye "Covid-19": ukuba intsholongwane kaCorona inokulichaphazela njani igazi kwinqanaba leselula.

Le ndlela inokusebenza njengenkqubo yokulumkisa kwangethuba ukuze kufunyanwe oobhubhane bexesha elizayo ngeentsholongwane ezingaziwayo.

Izazinzulu ziye zavavanya ngaphezulu kwe-4 yezigidi zeeseli zegazi kwizigulana ezili-17 ezinezifo ezinzima ezivela kwi-"Covid-19", kwaye ukusuka kubantu abali-14 abaye baphola, kunye nabantu abangama-24 abasempilweni njengeqela lokuthelekisa. Bafumanisa ukuba ubungakanani kunye deformation iiseli ezibomvu zegazi izigulane esi sifo aphambuke kabukhali kwabo abantu abasempilweni, kwaye oku kubonisa umonakalo kwezi seli kwaye unokuchaza umngcipheko ukwanda kwemithambo kunye embolism emiphungeni. kubantu abosulelekileyo.

I-Lymphocytes (olunye uhlobo lweeseli ezimhlophe zegazi ezinoxanduva lokuzikhusela komzimba) ziye zathamba kakhulu kwizigulana ze-Covid-19, zihlala zibonisa ukusabela okunamandla komzimba. yatshintshwa iinyanga ezisixhenxe emva kosulelo oluqatha.

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