Izinhlobo ezine zomdlavuza ezingabonwa kusenesikhathi

Izinhlobo ezine zomdlavuza ezingabonwa kusenesikhathi

Umbiko omusha uveze ukuthi ukusungulwa okusha kuzotholwa kusenesikhathi izinhlobo ezi-4 zesifo eminyakeni ngaphambi kokuxilongwa.

4 izinhlobo eziyingozi

Ubuye wengeza ngokuthi izinhlobo ezahlukene zezifo ezingatholwa ukuhlolwa zivela ngokukhomba ngokunembile izinguquko zeselula ezingaholela ekufeni komdlavuza womlomo wesibeletho, kanye nokucosha izimpawu ze-DNA kwezinye izinhlobo zomdlavuza, okusho ukuthi zingasetshenziswa esikhathini esizayo njengendlela yokuhlola umdlavuza webele kanye nesibeletho Umlomo wesibeletho namaqanda, ngokombiko oshicilelwe yiphephandaba laseBrithani "iThe Sun".

Ulwazi luphinde lwaveza ukuthi ukusebenza kwalokhu okusunguliwe uma kuhlolwa umdlavuza womlomo wesibeletho kuhle kakhulu kunezindlela ezikhona uma kuzanywa abantu abanalesi sifo okukhombisa ukuthi kwenze umehluko kulabo abasuke behlushwa wukushintsha kwamangqamuzana asezingeni eliphezulu nabadinga ukwelashelwa.

Mayelana nalabo abangenalo izinguquko kumaseli, kodwa abane-human papillomavirus (HPV) ebanga izigameko eziningi zomdlavuza womlomo wesibeletho, okusungulwe okutholakele u-55% wabantu uzoba nezinguquko kumaseli eminyakeni emine ezayo.

Thola ukuthi kungenzeka yini ukutheleleka

Ngokusho kwabacwaningi, lolu cwaningo beluqondise ku-DNA methylation, esebenza njengengqimba eyengeziwe phezu kwe-DNA, yona equkethe zonke izakhi zofuzo abantu abazithola kubazali bobabili.

Le methylation itshela amaseli ukuthi yiziphi izingxenye ze-asidi okufanele zifundwe.

Nakuba izici ezinjengokubhema, ukungcola, ukudla okungenamsoco kanye nokukhuluphala ngokweqile kungashintsha lezi zimpawu futhi kuguqule ukuziphatha kwamangqamuzana.

Ngokubhekisisa i-DNA methylation, ososayensi bakholelwa ukuthi bangakwazi ukubona umdlavuza futhi mhlawumbe babikezele ingozi yomuntu yokuthuthukisa isimila esikhathini esizayo.

ukuqapha iseli

Ngakolunye uhlangothi, izifundo zangaphambilini zokuhlolwa okusha zaphakamisa ukusebenzisa amasampula omlomo wesibeletho, kucatshangelwa ukunemba kokubikezela abesifazane abanomdlavuza webele noma wesibeletho.

Lolu cwaningo olusha, olushicilelwe kumagazini i-Genome Medicine 1254, luhlanganisa isampula yokuhlolwa komlomo wesibeletho kwabesifazane ababenoshintsho lwamangqamuzana kusukela kokuphansi kuya engozini enkulu, abesifazane abane-HPV ngaphandle kokushintsha kwamangqamuzana omlomo wesibeletho, kanye namasampula avela kwabesifazane ngaphandle koshintsho kumaseli abo omlomo wesibeletho. . I-cytology yomlomo wesibeletho eqhubekile yathuthukisa izinguquko zamaseli anobungozi obukhulu phakathi neminyaka emi-4.

USolwazi Martin Widschwinter wase-University College London uphakamise ukuthi ukugonyelwa igciwane elidala umdlavuza womlomo wesibeletho, osekusetshenziswa kabanzi, kuholela ekushintsheni kwenani nezinhlobo zegciwane elizungeza emphakathini.

Kodwa-ke, waphinde wagcizelela isidingo sokuvumelanisa indlela esetshenziswa ekuhlolweni komlomo wesibeletho ukuze iqhubeke nokuhlinzeka ngezinzuzo.

Wachaza ukuthi ukuhlola isampula efanayo yomlomo wesibeletho kunganikeza ulwazi mayelana nengozi yowesifazane yokuba nezinye izinhlobo ezinkulu ze-3 zomdlavuza, njengomdlavuza webele, we-ovary kanye nomdlavuza wesibeletho, egcizelela ukuthi ukwakha izinhlelo ezintsha neziphelele zokuhlola ingozi yokubikezela eduze nokuqoqwa komdlavuza wamanje. kanye namasampula omlomo wesibeletho asebenzayo anikeza amandla angempela okuvimbela umdlavuza esikhathini esizayo.

Ukulimala okuningi nokwamukelwa

Ngokulandelayo, u-Athena Lamnizos, oyi-CEO yenhlangano esiza abantulayo u-Eve Appeal, wamukele lolu daba, egcizelela isidingo sokusebenza ukuthuthukisa amathuluzi okuhlola kanye nezivivinyo zokubikezela ukuze kusebenze kangcono.

Ugcizelele ukuthi lena indlela entsha yokuhlonza ngokunembile izinhlobo zezilwane nokuvimbela izifo eziyingozi.

Kuyaphawuleka ukuthi iBrithani iqopha cishe izehlakalo ezintsha ezingama-3200 zomdlavuza womlomo wesibeletho unyaka ngamunye, kanye nokufa okungaba ngu-850, ngokusho kweCancer Research UK.

Cishe ingxenye yabesifazane abanalesi sifo iphila iminyaka eyi-10 noma ngaphezulu.