Ukusungulwa kwesayensi ukwelapha isifo senhliziyo

Ukusungulwa kwesayensi ukwelapha isifo senhliziyo

Ocwaningweni olusha olusha, ososayensi bazobhala kabusha i-DNA ngenhloso yokuthola ukwelashwa kokuqala emhlabeni kwezifo zenhliziyo zofuzo, kulokho okungachazwa ngokuthi "umzuzu obalulekile" emkhakheni wezokwelapha zenhliziyo.

Ngokwalokho okushicilelwe iwebhusayithi ye-"Boldsky", ososayensi abahamba phambili emhlabeni abavela e-United Kingdom, e-United States nase-Singapore babambisana kuphrojekthi ethi "Cure Heart" yokuklama umuthi wokugoma iziguli zenhliziyo. Ngokwemibiko yezindaba, iBritish Heart Foundation inikele ngama-euro ayizigidi ezingu-30 kulo msebenzi osindisa ukuphila.

Ngokokuqala ngqa, abacwaningi bazosebenzisa izindlela zofuzo ezinembile, ezaziwa ngokuthi ukuguqulwa okuyisisekelo, enhliziyweni ukuze baklame futhi bahlole ukwelashwa kokuqala kwezifo zemisipha yenhliziyo ezizuzwe ngofuzo, ngenjongo yokuphazamisa izakhi zofuzo ezinephutha.

Isifo senhliziyo esizuzwe njengefa

“Isifo senhliziyo esizuzwa njengefa” yigama elihlanganisa zonke izifo zenhliziyo ezidluliselwa kubazali ziye ezinganeni zabo, okungukuthi lapho umzali oyedwa noma bobabili benofuzo olukhubazekile noma oluguquliwe, kunethuba elingu-50/50 lokuludlulisela ezinganeni. Ezinye izifo zenhliziyo ezizuzwe njengefa zihlanganisa i-hypertrophic cardiomyopathy kanye ne-hypercholesterolemia.

Abanye abantu abanesifo senhliziyo sofuzo bangase bangabi nazo izimpawu eziningi, futhi lesi simo asitholakali kuze kube ngemva kokuhlaselwa yinhliziyo kungazelelwe, ukuquleka, noma ukufa kungazelelwe. Izibalo zikhomba ukuthi cishe u-0.8 kuya ku-1.2% wezingane ezisanda kuzalwa emhlabeni wonke zihlaselwa yisifo senhliziyo sofuzo.

Ithuba elingokomlando kanye neminyaka engama-30 yocwaningo

Ikomidi lezeluleko eliholwa nguSolwazi Sir Patrick Vallance, umeluleki omkhulu wesayensi kuhulumeni waseBrithani, likhethe ithimba elibhekele lolu cwaningo olubucayi, kanti uSolwazi Hugh Watkins, wase-University of Oxford kanye nomphenyi oyinhloko wephrojekthi yeCure Heart, uthe i-cardiomyopathy. yisifo esiyingozi kakhulu.Isimo "esijwayelekile" ngempela emhlabeni wonke futhi saziwa ukuthi sithinta umuntu oyedwa kwabangama-250.

UProfesa Watkins wanezela, echaza lolu cwaningo ngokuthi "ithuba lesikhathi esisodwa-in-a-generation" okuhloswe ngalo ukunciphisa ukukhathazeka okuqhubekayo mayelana nokufa okuzumayo, ukwehluleka kwenhliziyo kanye nesidingo esingaba khona sokufakelwa kwenhliziyo.

USolwazi Watkins wachaza, “Ngemuva kweminyaka engama-30 yocwaningo, kutholwe izakhi zofuzo eziningi ezithile kanye nokukhubazeka okunembangela ye-cardiomyopathy ehlukahlukene kanye nendlela esebenza ngayo. Kukholakala ukuthi kuzoba nokwelapha ngezakhi zofuzo okuzoqala ukuhlolwa nokuhlolwa kwemitholampilo phakathi neminyaka emihlanu ezayo.”

Ukulungiswa kwezakhi zofuzo ezinesici

Kwethenjwa ukuthi lolu hlelo olusha lokucwaninga luzolungisa unomphela ukuguqulwa kofuzo okubangela izinkinga zenhliziyo.

Kulo mongo, uChristine Seidman, uprofesa waseHarvard Medical School nomcwaningi oholayo owayehilelekile kulo msebenzi, wachaza ukuthi umgomo wawuwukuba “ukulungisa izinhliziyo” nokubuyisela ukusebenza kwazo okuvamile, echaza ukuthi “iningi lezinguquko ezavela ezigulini ziyahola. ukushintsha uhlamvu olulodwa ngokuphindaphindiwe.Kusukela kuyi-DNA code, okusho ukuthi kunekhambi ngokushintsha i-monogram nokubuyisela ikhodi.”

Ngokusho kwabacwaningi, amaphayona avela emazwenikazi amathathu futhi ahlukaniswa emkhakheni wokuhlelwa kwezakhi zofuzo ezintsha futhi ezinembe kakhulu ezihilelekile ocwaningweni, ukuhlolwa kwabantu akukakakwenziwa, kodwa ukuhlolwa kwezilwane kuye kwaphumelela futhi kuthembisa.

Abacwaningi bengeze ngokuthi kunethemba lokuthi abantu abasengcupheni yokuthola isifo senhliziyo ngofuzo ngenxa yokuba khona kofuzo olungalungile emindenini yabo bazokwazi ukuthola imishanguzo ngaphambi kokuba isifo sabo sikhule.