Ushukela ophezulu wegazi kanye ne-migraine

Ushukela ophezulu wegazi kanye ne-migraine

Kuyaziwa kabanzi ukuthi i-migraine ihlotshaniswa nezici ezihlobene ne-glucose, njenge-insulin yokuzila ukudla kanye nesifo sikashukela sohlobo 2, okuyizifo ezivamile ze-comorbid.

Kodwa ithimba lososayensi baseNyuvesi yaseQueensland e-Australia lithole ukuxhumana okuphathekayo kwezakhi zofuzo okungavula insimu entsha yokwelapha lezi zifo eziwohlozayo, ngokwe-New Atlas, icaphuna iphephabhuku elithi Human Genetics.

Ikhanda elibuhlungu kanye ne-migraines

Emininingwaneni, abacwaningi baseNyuvesi yaseQueensland baveze isixhumanisi sofuzo ezakhini zofuzo ezivela kubantu abaningi abane-migraine kanye nekhanda elibuhlungu, eliphinde liphikisana nezici zoshukela wegazi, okubangela ukulimala kabili kule nkinga yezempilo.

Kulinganiselwa ukuthi i-migraine ithinta ngaphezu kwe-10% yabantu bomhlaba, futhi ivame ngokuphindwe kathathu kwabesifazane.

"Kusukela ngo-1935, i-migraine ichazwe njengekhanda le-glycemic," kusho uDale Nyholt, uprofesa e-University of Queensland's Center for Genomics and Personal Health, enezela ukuthi "izici ze-glycemic ezifana nokumelana ne-insulin, i-hyperinsulinemia kanye ne-hypoglycemia Egazini, thayipha. Isifo sikashukela esingu-2 sihlotshaniswa nekhanda elibuhlungu kanye nemigraines.

Okutholakele kufike ngemuva kokuthi abacwaningi bahlaziye ama-genome ezinkulungwane zeziguli ze-migraine ukuze babone ukuthi kukhona yini izixhumanisi zofuzo ezingabonakala.

Baphinde benza ukuhlaziya kwezimpawu ezihlukene ukuze bahlonze izifunda ezijwayelekile ze-genomic, i-loci, izakhi zofuzo nezindlela, base behlolelwa ubudlelwano obuhlukahlukene.

Izinga le-insulin egazini

USolwazi uRafiq Islam, ongumcwaningi eNyuvesi yaseQueensland Centre, uthe, “Phakathi kwezici eziyisishiyagalolunye zikashukela osegazini ezacwaningwa, kutholakale ukuthi kunokuhlobana okubalulekile kofuzo phakathi kwe-insulin yokuzila (izinga le-insulin egazini) kanye ne-glycated hemoglobin ene-migraine nekhanda elibuhlungu. Nakuba i-glucose amahora amabili yayixhunyaniswa ngokofuzo nemigraines kuphela.

Ubuye wengeza ukuthi izifunda eziqukethe izici ezivamile ezisengozini yofuzo zitholwe phakathi kwe-migraine, i-insulin yokuzila, i-glucose yokuzila ukudla, ne-glycated hemoglobin, naphakathi kwekhanda elibuhlungu kanye nezifunda ezivamile ku-glucose, i-insulin yokuzila ukudla, i-glycated hemoglobin, ne-proinsulin yokuzila ukudla.

Ubuye wachaza ukuthi i-proinsulin noma i-pro-insulin iyi-pro-hormone eyandulela isigaba sokwenza i-insulin emzimbeni.

izindlela zokwelapha ezintsha

Ukuphazanyiswa kwezakhi zofuzo kuyisinyathelo esibalulekile esiya phambili ekuqondeni ukuthi i-migraines kanye nezici ezihambisanayo ze-glycemic zivela kanjani, futhi kuvula izindlela ezintsha nezijabulisayo zokungenelela kwezokwelapha.

U-Nyholt uphinde wembula ukuthi "ngokukhomba izinhlangano zofuzo, i-loci kanye nezakhi zofuzo ezihilelekile ekuhlaziyweni kocwaningo, inhlangano ye-causal yachazwa, ngaleyo ndlela ukuqonda okwengeziwe kobudlelwane phakathi kwe-migraine, ikhanda kanye nezici ze-glycemic kwafinyelelwa."

U-Islam wanezela ukuthi imiphumela yocwaningo “inganikeza izindlela zokuthuthukisa amasu amasha okwelapha okulawula izici ze-glycemic zeziguli eziphathwa yikhanda nekhanda, ikakhulukazi ukukhulisa izinga lokuzila ukudla kwe-insulin ukuze kuvikelwe ubuhlungu bekhanda.”

Izibikezelo zika-Frank Hogrepet ziphinda futhi