Amazinyo awusizo ekwelapheni ukudangala!!

Amazinyo awusizo ekwelapheni ukudangala!!

Ososayensi baseJohns Hopkins University e-United States benza ucwaningo olusha lokuhlola uqweqwe lwamazinyo akhishwe ezikhungweni zokwelapha amazinyo, ukuze bahlole izinga angasetshenziswa ngalo njengendlela yokwelapha ukucindezeleka, ngokusho kweBrithani “ I-Daily Mail” ishicilelwe.

Ukuhlolwa okusha kusekelwe kumbono wokuthi ama-stem cell ayinhloko, angakhula abe izinhlobo ezahlukene zamaseli akhethekile, ku-pulp angasiza ukugqugquzela ukwakheka kwama-neuron amasha ebuchosheni.

Ukwanda kokukhiqizwa kwama-neurons

Abacwaningi base-Johns Hopkins University bakholelwa ukuthi uma ama-neurons engeziwe, kuba ngcono ukuxhumana phakathi kwala maseli nezindawo zobuchopho ezinesibopho semizwa. Ama-stem cell nawo awahambisani nokuvuvukala, futhi kucatshangwa ukuthi ukucindezeleka kungase kuhlotshaniswe nokuvuvukala kwengqondo.

Ukuhlolwa kuza njengokuqhubeka kokutholakala kwempumelelo, okwenziwe ngaphambilini, ukuthi ama-antidepressants angashukumisa ama-stem cells ebuchosheni enze ama-neurons engeziwe.

i-serotonin

Kukholelwa futhi ukuthi ukuphazamisa amazinga amakhemikhali emizwa ebuchosheni njenge-serotonin ngandlela thize kuholela ekucindezelekeni, ikakhulukazi njengoba ama-antidepressants amaningi enzelwe ukusiza ukwandisa amazinga e-serotonin, kodwa kusasele ukuthi inkolelo-mbono yokungalingani kwamakhemikhali ebuchosheni ayiyona into eqondile. kufakazelwe, njengoba Ziningi ezinye izici ezingaholela ekucindezelekeni, okuhlanganisa ukuthambekela kofuzo kanye nezinkinga zempilo ezicindezelayo. Kodwa abacwaningi manje baphakamisa ukuthi ukukhula kwe-neuronal, kanye nokuxhumana phakathi kwama-neurons, kudlala indima ebalulekile.

isifunda se-hippocampal

Ucwaningo lwangaphambilini luthole ukuthi i-hippocampus, ehilelekile kwinkumbulo nezinqubo zemizwa ekuphenduleni izinkumbulo, incane ezigulini ezinokucindezeleka okungapheli.

Futhi abanye ochwepheshe baphakamise ukuthi i-hippocampus encane ingachaza ukuthi kungani kuthatha isikhathi eside ukuthi ama-antidepressants aqale ukusebenza. Athuthukisa amakhemikhali obuchopho njenge-serotonin ne-dopamine, kodwa kungathatha amasonto ambalwa ngaphambi kokuthi asebenze, ngakho-ke kungenzeka ukuthi isimo sengqondo siba ngcono njengoba ama-neurons amasha ekhula futhi akhe ukuxhumana okusha, inqubo ethatha amasonto.

Ikhuthaza ukukhula kwe-stem cell

Ucwaningo oluqhubekayo eYunivesithi yaseJohns Hopkins lubonise ukuthi imishanguzo yokucindezeleka ingakhuthaza ukukhula kwama-stem cells ebuchosheni. Ocwaningweni olusha, abantu abangama-48 abanokudangala bazonikezwa ama-stem cell akhishwe ku-pulp yamazinyo abanye abantu, ngaphezu kwe-antidepressant fluoxetine.

Amaseli ayacutshungulwa futhi ahlanzwe ngaphambi kokuba ajovwe ezingalweni zeziguli izikhathi ezine, amasonto amabili ngokuhlukana, kukhumbula ukuthi iqembu lokuqhathanisa lalithatha i-fluoxetine kuphela nsuku zonke.

Ama-anti-inflammatories

Ephawula ngale ndlela, uCarmine Pariant, uProfesa we-Biological Psychiatry eKing’s College London, uthi: “Ngesikhathi esifushane, ukucindezeleka kwandisa ukukhiqizwa kwamakhemikhali emzimbeni asiza ekulweni noma ekundizeni. Ngokwesibonelo, ukucindezeleka kwandisa ukuvuvukala, okuvikela [umuntu] ekungenweni izifo. Nokho, izingcindezi ezingokwengqondo nezenhlalo ezibangela ukucindezeleka, njengokungasebenzi, izinkinga zomshado noma ukushonelwa, ngokuvamile zithatha isikhathi eside. Ngokuhamba kwesikhathi, ukwanda kokuvuvukala kunciphisa ukuzalwa kwamangqamuzana obuchopho amasha kanye nokuxhumana phakathi kwamangqamuzana obuchopho, okuholela ekucindezelekeni.”

Unezela ukuthi ama-stem cells nawo “ayi-anti-inflammatory”, ngakho-ke ngaphezu kokwenza amangqamuzana obuchopho amasha, anganciphisa imiphumela yokuvuvukala yokucindezeleka ebuchosheni. Ama-stem cells ayaziwa ukuthi afinyelela ezindaweni lapho kunokuvuvukala khona, ngakho-ke azothola indlela yawo esuka egazini aye ebuchosheni.

Kuyini ukuthula okujezisayo?futhi ubhekana kanjani nalesi simo?