Ukwelashwa komdlavuza we-pancreatic ngenxa ye-corona

Ukwelashwa komdlavuza we-pancreatic ngenxa ye-corona

Ososayensi benze inqubekelaphambili ekuthuthukiseni umuthi wokugomela umdlavuza ngemuva kokusebenzisa ubuchwepheshe obufanayo obusetshenziswa ekukhiqizeni umuthi wokugomela igciwane iCorona, okhiqizwa inkampani yakwaPiontech-Pfizer.Umgomo, oklanyelwe ngokukhethekile isiguli ngasinye, ungakhuthaza amasosha omzimba ukuhlasela amangqamuzana omdlavuza.

Ochwepheshe abasungule ukwakhiwa komgomo we-Pfizer basebenzisane nodokotela baseNew York City ukuze bakhe umuthi wokugomela iziguli ezinomdlavuza wama-pancreas, ngokwalokho okushicilelwe yiphephandaba laseBrithani, "The Telegraph."

Imiphumela yocwaningo lomtholampilo lwesigaba I, olokuqala lwalolu hlobo, imenyezelwe kule mpelasonto engqungqutheleni yaminyaka yonke ye-American Society of Clinical Oncology (ASCO) eChicago.

Ososayensi banethemba lokuthi lokhu okutholakele kumemezela inkathi entsha yokwelashwa kwamanye umdlavuza okunzima ukuwelapha, njengoba umdlavuza we-pancreatic uvame ukubizwa ngokuthi "ingane eposta" yalezi zimila ezibulalayo.

Indlela yokusebenza yomgomo

Futhi mayelana nemininingwane yocwaningo, kwatholakala iziguli ezingamashumi amabili ezine-pancreatic adenocarcinoma (PDAC), emele cishe amaphesenti angama-90 azo zonke izimo zomdlavuza we-pancreatic, ocwaningweni.

Lezi ziguli zahlinzwa ukuze zisuse umdlavuza, futhi ngemva kwamahora angu-72 amasampula azo aqhuma athunyelwa e-BioNTech eJalimane ukuze athole ukwelashwa kanye nokugoma komuntu ngamunye, okunikezwa ngomthambo esigulini.

Iziguli nazo zithole i-immunotherapy ukusiza ukukhulisa impendulo yazo.

Ezinyathelweni zomgomo weCorona

Imithi yokugoma emisha isebenzisa i-mRNA, ikhodi yofuzo evela esimila, ukufundisa amangqamuzana omzimba ukwenza iphrotheni evuselela ukusabela kwamasosha omzimba, ubuchwepheshe obufanayo obusetshenziswa emithini yokugomela iCorona ekhiqizwe yinkampani iPfizer-BioNTech.

Umzimba ube usufunda ukuthi amangqamuzana omdlavuza empeleni awangaphandle bese uthumela ama-T cell ukuthi awafune futhi awabulale uma ebuya.

imiphumela ethembisayo

Iziguli eziyishumi nesithupha zithole imithamo yokuqala kweyisishiyagalolunye yomuthi wokugoma emasontweni ayisishiyagalolunye ngemva kokuhlinzwa, futhi ingxenye yawo yakhiqiza impendulo ebalulekile yokuzivikela komzimba.

Futhi, zonke iziguli eziyisishiyagalombili bezingenawo umdlavuza ezinyangeni eziyi-18, okuphakamisa ukuthi amaseli e-T acushwe wumgomo ayeke ukuphindelela umdlavuza.

Kodwa-ke, iziguli eziyisishiyagalombili azizange zisabele emuthini wokugoma, kuyilapho eziyisithupha zabona umdlavuza wazo ubuya ngemva nje konyaka, futhi abacwaningi basaphenya ukuthi kungani ingxenye yeqembu ingaphendulanga.

USolwazi Ozlem Turise, umsunguli kanye nomqondisi wezokwelapha we-BioNTech, uthe ngamaphesenti amahlanu kuphela eziguli ezinomdlavuza we-pancreatic abasabela ekwelashweni.

“Sizibophezele ekubhekaneni nale nselelo ngokwakha ucwaningo lwethu oselunesikhathi eside saluthola mayelana nemithi yokugomela umdlavuza futhi sizame ukuqhamuka nesisekelo esisha ekwelapheni izimila ezinzima kangaka ukuzelapha,” engeza.