Isizathu sokulahlekelwa umuzwa wokuhogela ngemuva kokutheleleka ngeCorona

Isizathu sokulahlekelwa umuzwa wokuhogela ngemuva kokutheleleka ngeCorona

Ucwaningo olusha, olushicilelwe kumagazini iScience Translational Medicine, lukhombisa lokho

Ukutheleleka kwe-SARS-CoV-2 kuhlala kuhlasela amasosha omzimba kumaseli ezinzwa emakhaleni.

Lokhu kubangela ukuncipha kwenani lalezi zinzwa, futhi kwenza abantu bangakwazi ukuhogela ngendlela abajwayele ukwenza ngayo.

Ephendula umbuzo owadida ochwepheshe, isazi sezinzwa uBradley Goldstein waseDuke University eNorth Carolina uthi:

“Ngenhlanhla, abantu abaningi abanomuzwa oshintshile wokuhogela ngesikhathi sesigaba esibi kakhulu sokutheleleka ngegciwane bazophinde bakuthole phakathi nesonto noma amabili ezayo, kodwa abanye abakwazi.

Sidinga ukuqonda kangcono ukuthi kungani lesi sigaba sabantu sizoqhubeka nokulahlekelwa umuzwa wokuhogela izinyanga ngisho neminyaka ngemuva kokutheleleka nge-SARS-CoV-2. "

isizathu

Ngalesi sizathu, ithimba lezokwelapha lifunde amasampula ezicubu zamakhala athathwe kubantu abangama-24, kuhlanganisa abayisishiyagalolunye abanenkinga yokulahlekelwa umuzwa wokuhogela isikhathi eside ngemuva kokutheleleka nge-“Covid-19”.

Lesi sicubu sithwala amangqamuzana ezinzwa anesibopho sokuthola iphunga.

Ngemva kokuhlaziya okuningiliziwe, abacwaningi baphawula ukwanda okwandile kwama-T cell, uhlobo lwamangqamuzana amhlophe egazi olusiza umzimba ukuba ulwe nezifo.

Lawa maseli e-T ayeshayela impendulo yokuvuvukala ngaphakathi kwekhala.

Futhi ithimba lezokwelapha lithole ukuthi ama-T cell enza umonakalo omkhulu kunokuhle, njengoba elimaza izicubu ze-epithelial olfactory, futhi athola ukuthi inqubo yokuvuvukala isabonakala nasezicutshini lapho i-SARS-CoV-2 ingatholwanga.

“Imiphumela iyamangalisa,” kusho uGoldstein. Kucishe kufane nohlobo oluthile lwenqubo efana ne-autoimmune emakhaleni."

ukululama kwephunga

Ngenkathi inani lama-neurons enzwa enukayo laliphansi kubahlanganyeli bocwaningo ababelahlekelwe umuzwa wabo wokuhogela

Abacwaningi babika ukuthi amanye ama-neurons abonakala ekwazi ukuzilungisa ngisho nangemva kokuqhuma kwama-T cell - uphawu olukhuthazayo.

Ithimba lifune ukuphenya kabanzi ngezindawo ezithile zezicubu ezilimele, kanye nezinhlobo zamaseli ezihilelekile.

Okungase kuholele ekuthuthukisweni kokwelashwa okungenzeka kulabo abanenkinga yokulahlekelwa iphunga isikhathi eside.

"Sithemba ukuthi ukuguqula impendulo engavamile yokuzivikela komzimba noma ukulungiswa ngaphakathi kwekhala lalezi ziguli kuzosiza okungenani ukubuyisela umuzwa wokuhogela," kusho uGoldstein.

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