Menene alaƙa tsakanin cututtukan tsarin narkewa da ƙwaƙwalwa?

Menene alaƙa tsakanin cututtukan tsarin narkewa da ƙwaƙwalwa?

Nazarin dabbobi na baya-bayan nan ya nuna cewa cutar Alzheimer na iya kamuwa da ita ga ƙananan beraye ta hanyar canja wurin ƙwayoyin cuta na hanji, yana tabbatar da alaƙa tsakanin tsarin narkewar abinci da lafiyar kwakwalwa, bisa ga abin da shafin yanar gizon Science Alert ya buga, yana ambaton mujallar Scientific Reports.

Mummunan sakamako na kumburi

Wani sabon bincike ya kara goyon baya ga ka'idar cewa kumburi na iya zama hanyar da ke yin mummunan tasiri ga lafiyar kwakwalwa "An gano cewa mutanen da ke fama da cutar Alzheimer sun fi kumburin hanji," in ji masanin ilimin psychologist Barbara Bendlin na Jami'ar. Wisconsin." Hoto na kwakwalwa, wadanda ke da kumburi mafi girma a cikin hanji suna da matakan amyloid [protein clumps] ginawa a cikin kwakwalwarsu."

Gwajin Calprotectin

Margo Heston, masanin ilimin cututtuka a Jami'ar Wisconsin, da ƙungiyar masu bincike na duniya sun gwada calprotectin, alamar kumburi, a cikin samfurori na stool daga mutane 125 da aka zaba daga binciken rigakafin cutar Alzheimer guda biyu. Mahalarta sun yi gwaje-gwajen fahimi da yawa a lokacin da suka shiga cikin binciken, baya ga tambayoyin tarihin iyali da gwaje-gwaje don manyan haɗarin cutar Alzheimer. An yi gwajin gwaji na asibiti don alamun kumburin furotin amyloid, alamar gama gari na cutar da ke da alhakin yanayin neurodegenerative. Duk da yake matakan calprotectin sun kasance mafi girma a cikin tsofaffi marasa lafiya, sun fi bayyana a cikin wadanda ke da amyloid plaques halayyar cutar Alzheimer.

Alzheimer ko raunin ƙwaƙwalwar ajiya

Matakan sauran alamomin halittu na cutar Alzheimer kuma sun karu tare da matakan kumburi, kuma ƙimar gwajin ƙwaƙwalwar ajiya ta ragu yayin da calprotectin ya tashi. Ko da mahalarta waɗanda ba a gano suna da cutar Alzheimer ba suna da ƙarancin ƙwaƙwalwar ajiya tare da matakan calprotectin mafi girma.

Canje-canje a cikin ƙwayoyin hanji

Binciken dakin gwaje-gwaje ya nuna a baya cewa sinadarai daga kwayoyin cuta na hanji na iya tayar da siginar kumburi a cikin kwakwalwa. Sauran nazarin sun kuma sami karuwar kumburin hanji a cikin marasa lafiya na Alzheimer idan aka kwatanta da ƙungiyar kulawa.
Heston da abokan aikinta suna ba da shawarar cewa canje-canje a cikin microbiome yana haifar da canje-canje a cikin gut wanda ke haifar da kumburi a matakin tsarin. Wannan kumburin yana da sauƙi amma na yau da kullun, kuma yana haifar da lahani da lalacewa mai ci gaba wanda a ƙarshe yana yin katsalandan tare da fahimtar shingen jiki.

Katangar kwakwalwar jini

"Ƙara haɓakar ƙwayar hanji zai iya haifar da haɓakar ƙwayoyin ƙwayoyin ƙwayoyin cuta da gubobi waɗanda aka samo daga lumen na hanji a cikin jini, wanda ke haifar da kumburi na tsarin, wanda hakan zai iya raunana shingen jini-kwakwalwa kuma yana iya inganta kumburi," in ji Federico Re, farfesa. na kwayoyin cuta a Jami'ar Jihar Wisconsin. jijiyoyi, [hakan haifar da] raunin jijiya da neurodegeneration."

Canje-canjen abinci

Masu bincike a halin yanzu suna gwaji tare da berayen dakin gwaje-gwaje don ganin ko canje-canje a cikin abincin da ke hade da haɓakar kumburi na iya haifar da nau'in cutar Alzheimer a cikin berayen.
Duk da shekaru da yawa na bincike, har yanzu babu wani ingantaccen magani ga miliyoyin mutanen da ke fama da cutar Alzheimer a duk duniya. Amma tare da fahimtar hanyoyin nazarin halittu, masana kimiyya suna samun kusanci da kusanci.

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