Magani ga masu ciwon asma wanda ke rage illar sa

Magani ga masu ciwon asma wanda ke rage illar sa

Yin amfani da ilimin ilimin halitta don rage kumburin huhu ya sa kashi 92 cikin XNUMX na mutanen da ke fama da asma mai tsanani don rage yawan allurai na yau da kullun na steroids ba tare da cutar da alamun su ba, sabon binciken ya gano. Wadannan binciken suna nufin cewa mutanen da ke fama da asma mai tsanani na iya rage haɗarin mummunan tasirin da ke tattare da amfani da steroid na dogon lokaci, a cewar New Atlas, yana ambaton The Lancet.

Daga cikin kimanin mutane miliyan 300 da ke fama da asma a duniya, kusan kashi 3 zuwa 5% na fama da asma mai tsanani, suna fama da karancin numfashi a kullum, da daurewar kirji da tari wanda yakan kai ga asibiti. Mafi yawan masu fama da cutar asma suna da nau'in nau'in nau'in nau'in asma mai suna eosinophilic asthma, wanda ke da nau'i mai yawa na ƙwayoyin rigakafi (eosinophils) a cikin jini wanda ke haifar da kumburi da kumburin hanyoyin iska.

Guji yiwuwar mummunan sakamako

Maganin da aka ba da shawarar don ciwon asma na eosinophilic, bisa ga Global Initiative for Asthma (GINA), shine haɗin yau da kullum na budesonide (wani corticosteroid inhaled don sarrafa kumburi) da kuma formoterol (mai aikin bronchodilator mai tsawo don shakatawa da bude hanyoyin iska). Wannan magani, wanda aka sani da ICS ko "steroid," an fi son shi a kan masu aikin "ceto" na gajeren lokaci saboda tasirin anti-mai kumburi da bronchodilator. Amma yin amfani da dogon lokaci yana iya zama matsala, saboda yana da alaƙa da ƙumburi na baka, osteoporosis, ciwon sukari, raunin garkuwar jiki, da kuma cataracts.

Wani bincike, wanda masana kimiyya daga King's College London suka gudanar a kan marasa lafiya a kasashe hudu: Birtaniya, Faransa, Italiya da Jamus, sun bincika ko jiyya tare da benralizumab (maganin ilimin halitta) ya ba wa mutanen da ke fama da ciwon asma mai tsanani don rage adadin ICS ba tare da rasa ba. sarrafa alamun su.asthma.

David Jackson, shugaban tawagar binciken, ya ce: "Magungunan ilimin halitta irin su benralizumab sun kawo sauyi mai tsanani game da cutar asma ta hanyoyi da yawa, kuma sakamakon sabon binciken ya nuna a karon farko cewa za a iya guje wa cutar da ke da alaka da steroid ga yawancin. marasa lafiya da ke amfani da wannan magani."

Ana ba da Benralizumab ta hanyar allurar subcutaneous sau ɗaya kowane mako huɗu don allurai uku na farko, sannan sau ɗaya kowane mako takwas.

Sakamakon binciken ya nuna cewa, a gaba ɗaya, 92% na mahalarta sun rage yawan adadin ICS. Musamman, 15% daga cikinsu sun rage adadin zuwa matsakaicin matsakaici, 17% zuwa ƙananan kashi, da 61% zuwa kashi kamar yadda ake buƙata kawai. Har ila yau, 91% na mahalarta ba su fuskanci wani mummunan bayyanar cututtuka ba a lokacin da ake yin tapering.

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