Daawooyinkani waxay keeni karaan indhaha indhaha

Daawooyinkani waxay keeni karaan indhaha indhaha

Iyadoo calaamadaha kor u kaca kolestaroolka dhiigga ay xaqiijinayaan dhibaatada aragga, koox saynisyahano ah ayaa soo gabagabeeyey in bukaanada leh kala duwanaansho hidde ah oo ku xiran daawooyinka statin ay halis dheeraad ah u tahay inay yeeshaan indho-beelka.

Natiijooyin cilmi-baaris oo hore ayaa soo jeediyay in ay jiraan caddaymo muujinaya in statins ay kordhin karaan khatarta ah in ay yeeshaan cataracts, sida laga soo xigtay daabacaadda, iyada oo la tixraacayo Joornaalka Ururka Wadnaha ee Maraykanka (JAHA).

statins kaliya

Iyadoo cilmi-baaristii ugu dambeysay ay xustay in cilmi-baarayaashu ay ogaadeen in hidde-sideyaasha qaarkood ee ku dayanaya waxqabadka statins ay sidoo kale si madax-bannaan u kordhin karaan khatarta ah in ay ku dhacaan indhaha indhaha.

Waxay sharraxeen in dawooyinkani ay caadi ahaan hoos u dhigaan heerarka LDL kolestaroolka iyagoo joojinaya enzyme la yiraahdo HMG-CoA-reductase (HMGCR).

Si kastaba ha noqotee, cilmi baaris cilmiyeed ayaa xaqiijisay in kala duwanaanshiyaha gobolka HMGCR ee hiddo-wadaha bini'aadamka ay saameeyaan sida bukaanku u dheefshiido kolestaroolka.

Dhanka kale, madaxa cilmi-baadhista, Professor Jonas Jahaus, oo ka tirsan kooxda Genetics Wadnaha ee Shaybaarka Molecular Cardiology Laboratory ee Waaxda Sayniska Biomedical ee Jaamacadda Copenhagen ee Danmark, ayaa sheegay in daraasaddu ay awoodi wayday inay hesho wax xiriir ah oo ka dhexeeya kuwa cusub. Daawooyinka aan statin ahayn iyo dawooyinka guud: hoos u dhigista dufanka iyo khatarta caadka, markaa waxay u badan tahay in saamayntani ay si gaar ah ula xiriirto statins.

Si kastaba ha ahaatee, wuxuu carrabka ku adkeeyay muhiimada faa'iidooyinka statins inay hoos u dhigaan heerarka lipoprotein-ka cufan ee dadka leh heerarka sare ee kolestaroolka, isaga oo sharxaya inay ka miisaan badan yihiin khatarta yar ee horumarinta cataracts.

5 kala duwanaansho hidde caadi ah

Cilmi-baadhayaashu waxay falanqeeyeen xogta hidda-socodka ee in ka badan 402,000 oo qof, iyaga oo diiradda saaraya shan nooc oo hore loo aqoonsaday noocyo kala duwan oo hidde ah oo hoos u dhigaya kolestaroolka LDL.

Dhibcaha hidda-socodka ayaa markaa la xisaabiyay iyadoo lagu salaynayo saamaynta horay loo cayimay ee nooc kasta oo LDL-kolesterol ah. Xogta koodka hidde-sidaha ayaa markaa la baadhay si loo aqoonsado sidayaal isbeddel naadir ah oo ku jira hidda-wadaha HMGCR ee loo yaqaan beddelka shaqada luminta ee la filayo.

"Marka aan qaadno isbeddelka shaqada ee lumay, hidde-siduhu aad ayuu u yar yahay inuu shaqeeyo," Professor Jahaus ayaa yidhi. Hadii hiddasidaha HMGCR aanu shaqayn, jidhku ma samayn karo borotiinkan. Si fudud loo dhigo, isbeddelka shaqada ee lumay ee hidda-wadaha HMGCR waxay u dhigantaa qaadashada statin.”
Dhibcaha halista hidde-sidaha

Natiijooyinka daraasadda ayaa shaaca ka qaaday in khataraha hidde-sidaha ee ay sababto HMGCR ay dadka ka dhigayso inay aad ugu dhowdahay inay yeeshaan cataract.

Mid kasta oo 38.7 mg/dL hoos u dhaca LDL-cholesterol marka la eego dhibcaha hidde-sideyaasha ayaa lala xiriiriyay 14% khatarta ah in uu ku dhaco indhaha indhaha iyo 25% khatarta ah ee kordhinta qalliinka.

Saamayn togan

Marka la eego saamaynta togan, cilmi-baarayaashu waxay soo wariyeen in xaddidaadda ugu weyn ee daraasadda ay tahay in marka la qaado noocyadan hidde-sideyaasha ah ay keenayaan khatarta nolosha oo dhan ee horumarinta caadka, khatartan waa in aan loo qiimeyn si la mid ah dadka bilaabay qaadashada statins dambe ee noloshooda. Statins, taas oo yaraynaysa heerka kolestaroolka ee dhiigga. Qiimayn dheeraad ah oo ururkan lagu sameeyo tijaabooyin caafimaad oo dheeraad ah ayaa loo baahan yahay si loo xaqiijiyo natiijooyinkan.

Waxa xusid mudan in ka-hortagga kolestaroolka sare iyo khatarta uu keeno ay leedahay habab kala duwan, kuwaas oo ay ugu muhiimsan yihiin in wax ka beddelka hab-nololeedka iyo jimicsi joogto ah, iyada oo la raacayo nafaqo habboon, iyo in aan sigaar cabbin.

Iyo sidoo kale la socodka dhakhtarka haddii ay dhacdo dhaawac iyo u hoggaansanaanta rijeetada si looga fogaado dhacdooyinka dhibaatooyinka khatarta ah.