Sidee buu walaacu ugu gudbiyaa habka hurdadaada iyo maskaxdaada?

Sidee buu walaacu ugu gudbiyaa habka hurdadaada iyo maskaxdaada?

Dad badan ayaa og in walbahaarka uu keeni karo hurdo la'aan. Laakiin markii ugu horreysay, koox saynisyahano ah ayaa awooday inay ogaadaan sida walaacu u kiciyo unugyada maskaxda waqti qaldan inta lagu jiro marxaladaha hurdada, taasoo keenta hurdo la'aan iyo tayada nasashada oo liita, sida lagu daabacay mareegta New Atlas oo soo xiganeysa. joornaalka Biyolojiga hadda.

Saamaynta jireed

Iyadoo la baarayo saameynta jireed ee walaaca hurdada ee qaabka jiirka, Saynisyahanada Jaamacadda Pennsylvania waxay kormeereen dhaqdhaqaaqa aagga preoptic (POA) ee hypothalamus inta lagu jiro hurdada caadiga ah. Saynis yahanadu waxay ogaadeen in glutamatergic neurons, VGLUT2, ay aad u firfircoon yihiin inta lagu jiro soo jeedka oo ay ku yar yihiin hurdo NREM iyo REM.

Hurdada NREM waxay ka kooban tahay saddex marxaladood oo wareegga hurdada ah ee 90-daqiiqo ah, iyadoo hurdada REM ay tahay marxaladda afraad.

Marxalad kastaa waxay ka kooban tahay kayd isku xidhan oo ah shaqada maskaxda iyo jidhka kuwaas oo lagama maarmaan u ah caafimaadka iyo xusuusta.

"Daqiiqado xiiso leh"

Laakiin walbahaarka wuxuu sababi karaa VGLUT2 inuu dab ku dhufto wejiyada NREM, marka sida caadiga ah la jabiyo, taasoo keenaysa "xakamaynta yar yar" ee carqaladeeya wareegga caadiga ah. Markii ay saynisyahannadu kiciyeen neerfayaasha, waxa kor u kacay xamaasaddan daahsoon.

Iyadoo hurdo la'aantu ay saamayso xusuusta, shaqada difaaca, habaynta shucuureed iyo rabitaanka cuntada, waxay si isa soo taraysa ugu xidhan tahay khatarta sii kordheysa ee cudurada iyo dhibaatooyinka caafimaadka maskaxda.

Dhibaatooyinka hurdada

"Marka aad haysato habeen xun oo hurdo ah, waxaad ogaanaysaa in xusuustaadu aysan u fiicneyn sida caadiga ah, ama in dareenkaaga oo dhan uu isku qasan yahay meel kasta - laakiin habeen xun oo hurdo ah ayaa carqaladeeya habab kale oo badan," ayuu yidhi Xinghai Zhong, oo ah kaaliyaha borofisar ku takhasusay cilmiga neerfaha ee Jaamacadda Pennsylvania.

Jooji saamaynta xun

Cilmi-baadhayaashu waxay ku doodayaan in daah-furka cusubi aanu xalin karin sababta asaasiga ah ee dhibaatada, taas oo ah walaac gaar ah, laakiin waxay daaha ka qaadaysaa in ay jirto suurtogalnimo weyn oo awood u leh in la beegsado nidaamka VGLUT2 si loo xakameeyo xiisahan qarsoon. Cilmi-baadhayaashu waxay aaminsan yihiin inay si gaar ah muhiim ugu tahay dadka qaba hurdo-xumo ama xaalado kale sida walaaca iyo xanuunka walbahaarka ee post-traumatic stress (PTSD).

"Waa muhiim in la fahmo arrimaha bayoolojiga ah ee dhaqaajiya dhaqdhaqaaqa maskaxda marxaladahan muhiimka ah ee hurdada, iyo sida kicinta ay ka mid tahay walaaca ay u carqaladayn karto, si aan maalin u horumarino daweyn si ay uga caawiso shakhsiyaadka inay helaan hurdo nasasho leh oo u oggolaanaya maskaxdooda dhamaystiro hababkan muhiimka ah,” Chung ayaa raaciyay.

Horumarinta daawaynta cusub

Cilmi-baarayaashu waxay sidoo kale ogaadeen in markii ay joojiyeen VGLUT2 neurons, microarousal inta lagu jiro hurdada NREM ayaa sidoo kale hoos u dhacday. Xilliyada hurdada ee NREM ee soo celinta ayaa sii dheeraaday.

"Glutamatergic neurons ee hypothalamus waxay na siinaysaa bartilmaameed rajo leh oo lagu horumarinayo daaweynta xanuunka hurdada ee la xidhiidha walaaca," ayuu yiri cilmi-baadhaha hogaanka ah Jennifer Smith, isagoo xusay in "awoodda lagu yareeyo carqaladeynta inta lagu jiro marxaladaha muhiimka ah ee hurdada aan REM ahayn iyadoo la xakameynayo dhaqdhaqaaqa VGLUT2 waxay noqon doontaa Faa'iido leh." Gogoldhig u ah shakhsiyaadka la ildaran hurdo la'aanta sababtoo ah cilladaha sida hurdo la'aanta ama PTSD.

Saadaasha jacaylka Scorpio ee sanadka 2024